Correlation Between Acoustic Rhinometry, Computed Rhinomanometry And Cone-beam Computed Tomography In Mouth Breathers With Transverse Maxillary Deficiency

To provide clinical information and diagnosis in mouth breathers with transverse maxillary deficiency with posterior crossbite. Numerous exams can be performed; however, the correlation among these exams remains unclear. Objective: To evaluate the correlation between acoustic rhinometry, computed rhinomanometry, and cone-beam computed tomography in mouth breathers with transverse maxillary deficiency. Methods: A cross-sectional study was conducted in 30 mouth breathers with transverse maxillary deficiency (7-13 y.o.) patients with posterior crossbite. The examinations assessed: (i) acoustic rhinometry: nasal volumes (0-5. cm and 2-5. cm) and minimum cross-sectional areas 1 and 2 of nasal cavity; (ii) computed rhinomanometry: flow and average inspiratory and expiratory resistance; (iii) cone-beam computed tomography: coronal section on the head of inferior turbinate (Widths 1 and 2), middle turbinate (Widths 3 and 4) and maxilla levels (Width 5). acoustic rhinometry and computed rhinomanometry were evaluated before and after administration of vasoconstrictor. Results were compared by Spearman's correlation and Mann-Whitney tests (α = 0.05). Results: Positive correlation was observed between: (i) flow evaluated before administration of vasoconstrictor and Width 4 (Rho = 0.380) and Width 5 (Rho = 0.371); (ii) Width 2 and minimum cross-sectional areas 1 evaluated before administration of vasoconstrictor (Rho = 0.380); (iii) flow evaluated before administration of vasoconstrictor and nasal volumes of 0-5. cm (Rho = 0.421), 2-5. cm (Rho = 0.393) and minimum cross-sectional areas 1 (Rho = 0.375); (iv) Width 4 and nasal volumes of 0-5. cm evaluated before administration of vasoconstrictor (Rho = 0.376), 2-5. cm evaluated before administration of vasoconstrictor (Rho = 0.376), minimum cross-sectional areas 1 evaluated before administration of vasoconstrictor (Rho = 0.410) and minimum cross-sectional areas 1 after administration of vasoconstrictor (Rho = 0.426); (v) Width 5 and Width 1 (Rho = 0.542), Width 2 (Rho = 0.411), and Width 4 (Rho = 0.429). Negative correlation was observed between: (i) Width 4 and average inspiratory resistance (Rho = -0.385); (ii) average inspiratory resistance evaluated before administration of vasoconstrictor and volume of 0-5. cm (Rho = -0.382), and average expiratory resistance evaluated before administration of vasoconstrictor and minimum cross-sectional areas 1 (Rho = -0.362). Conclusion: There was correlation between acoustic rhinometry, computed rhinomanometry, and cone-beam computed tomography in mouth breathers with transverse maxillary deficiency. © 2016 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial

Spirometry And Volumetric Capnography In Lung Function Assessment Of Obese And Normal-weight Individuals Without Asthma

To analyze and compare lung function of obese and healthy, normal-weight children and adolescents, without asthma, through spirometry and volumetric capnography. Methods: Cross-sectional study including 77 subjects (38 obese) aged 5-17 years. All subjects underwent spirometry and volumetric capnography. The evaluations were repeated in obese subjects after the use of a bronchodilator. Results: At the spirometry assessment, obese individuals, when compared with the control group, showed lower values of forced expiratory volume in the first second by forced vital capacity (FEV1/FVC) and expiratory flows at 75% and between 25 and 75% of the FVC (p <0.05). Volumetric capnography showed that obese individuals had a higher volume of produced carbon dioxide and alveolar tidal volume (p <0.05). Additionally, the associations between dead space volume and tidal volume, as well as phase-3 slope normalized by tidal volume, were lower in healthy subjects (p <0.05). These data suggest that obesity does not alter ventilation homogeneity, but flow homogeneity. After subdividing the groups by age, a greater difference in lung function was observed in obese and healthy individuals aged >11 years (p <0.05). Conclusion: Even without the diagnosis of asthma by clinical criteria and without response to bronchodilator use, obese individuals showed lower FEV1/FVC values and forced expiratory flow, indicating the presence of an obstructive process. Volumetric capnography showed that obese individuals had higher alveolar tidal volume, with no alterations in ventilation homogeneity, suggesting flow alterations, without affecting lung volumes. © 2017 Sociedade Brasileira de Pediatria

Validation of fracture envelopes of structural adhesives for mixed-mode strength prediction of bonded joints

In the design of adhesive structures, it is extremely important to accurately predict their strength and fracture properties (critical strain energy release rate in tension, GIC, and shear, GIIC). In most cases, the loads occur in mixed-mode (tension plus shear). Thus, it is of great importance the perception of fracture in these conditions, namely of the strain energy release rates in tension, GI, and shear, GII, relative to different crack propagation criteria or fracture envelopes. This comparison allows to determine the most suitable energetic propagation criterion to be used in cohesive zone models (CZM). The main objective of this work is to verify, by CZM, which is the power parameter (?) that best suits the energetic crack propagation criterion for CZM modelling, using single-lap joints (SLJ) and double-lap joints (DLJ) with aluminium adherends and bonded with three different adhesives. With this purpose, numerical simulations of the SLJ and DLJ are carried out, and the maximum load (Pm) is compared with experiments. For the Araldite AV138 and Araldite鮮 2015, the energetic criterion resulting from the experimental work provided matching numerical results and, thus, the fracture envelopes were validated. The Sikaforce� 7752 results were slightly offset due to CZM law shape issues

Pulsed Direct And Constant Direct Currents In The Pilocarpine Iontophoresis Sweat Chloride Test

Background: The classic sweat test (CST) is the golden standard for cystic fibrosis (CF) diagnosis. Then, our aim was compare the production and volume of sweat, and side effects caused by pulsed direct current (PDC) and constant direct current (CDC). To determine the optimal stimulation time (ST) for the sweat collection. To verify the PDC as CF diagnosis option. Methods: Prospective study with cross-sectional experimental intervention. Experiment 1 (right arm): PDC and CDC. ST at 10 min and sweat collected at 30 min. Currents of 0.5; 0.75; 1.0 and 1.5 mA and frequencies of 0, 200, 1,000 and 5,000 Hz applied. Experiment 2 (left arm): current of 1.0 mA, ST at 5 and 10 min and sweat collected at 15 and 30 min with frequencies of 0; 200; 1,000 and 5,000 Hz applied Experiments 1 and 2 were performed with current density (CD) from 0.07 to 0.21 mA/cm2. Experiment 3: PDC was used in typical CF patients with two CFTR mutations screened and or with CF diagnosis by rectal biopsy and patients with atypical CF. Results: 48 subjects (79.16% female) with average of 29.54 ± 8.87 years old were enrolled. There was no statistical difference between the interaction of frequency and current in the sweat weight (p = 0.7488). Individually, positive association was achieved between weight sweat and stimulation frequency (p = 0.0088); and current (p = 0.0025). The sweat production was higher for 10 min of stimulation (p = 0.0023). The sweat collection was better for 30 min (p = 0.0019). The skin impedance was not influenced by ST and sweat collection (p > 0.05). The current frequency was inversely associated with the skin impedance (p < 0.0001). The skin temperature measured before stimulation was higher than after (p < 0.0001). In Experiment 3 (29 subjects) the PDC showed better kappa index compared to CDC (0.9218 versus 0.5205, respectively). 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Fracture modelling of adhesively-bonded joints by an inverse method

Nowadays, any structure must have strength, robustness and lightness, which has increased the industrial interest and research efforts in adhesive joining, mainly in the improvement of strength and fracture properties of adhesives. Thus, in recent years, the use of adhesive joints in industrial applications has gradually grown, replacing some traditional bonding methods, since they have advantages such as reduced stress concentrations, reduced weight and cost, and ease of processing/manufacturing. In this work, the cohesive laws of three adhesives, Araldite AV138, Araldite鮮 2015 and Sikaforce� 7752, were obtained by the application of an inverse adjustment method between the numerical and experimental load-displacement curves (P-?) of Double-Cantilever Beam (DCB) tests for tensile characterization and End-Notched Flexure (ENF) tests for shear characterization. Next, these laws were validated with experimental data of single-lap joints (SLJ) and double-lap joints (DLJ), using Abaqus�. For the Araldite� AV138 and Araldite� 2015, in tension and shear, the triangular law accurately predicted the behaviour of the SLJ and DLJ. For the Sikaforce� 7752, the triangular law did not suitably fit the experimental results. Due to its ductility, the Sikaforce� 7752 could be modelled with a trapezoidal law for improved accuracy

Erratum To: Quality Of Sweat Test (st) Based On The Proportion Of Sweat Sodium (na) And Sweat Chloride (cl) As Diagnostic Parameter Of Cystic Fibrosis: Are We On The Right Way?

During production of the original article [1] the Methods section included an incorrect sentence. The following sentence "For the analysis of variables with numerical distribution, Fisher's exact test and one-way analysis of variance were used" should be corrected as "For the analysis of variables with numerical distribution, Student's t-test and one-way analysis of variance were used". © The Author(s).12