25 research outputs found
Expression of SOX2, NANOG and OCT4 in a mouse model of lipopolysaccharide-induced acute uterine injury and intrauterine adhesions
Exosomes derived from human menstrual blood-derived stem cells alleviate fulminant hepatic failure
Purinergic signalling and immune cells
This review article provides a historical perspective on the role of purinergic signalling in the regulation of various subsets of immune cells from early discoveries to current understanding. It is now recognised that adenosine 5'-triphosphate (ATP) and other nucleotides are released from cells following stress or injury. They can act on virtually all subsets of immune cells through a spectrum of P2X ligand-gated ion channels and G protein-coupled P2Y receptors. Furthermore, ATP is rapidly degraded into adenosine by ectonucleotidases such as CD39 and CD73, and adenosine exerts additional regulatory effects through its own receptors. The resulting effect ranges from stimulation to tolerance depending on the amount and time courses of nucleotides released, and the balance between ATP and adenosine. This review identifies the various receptors involved in the different subsets of immune cells and their effects on the function of these cells
Estrogen Receptor-α Agonists Promote Angiogenesis in Human Myometrial Microvascular Endothelial Cells
Niche matters: The comparison between bone marrow stem cells and endometrial stem cells and stromal fibroblasts reveal distinct migration and cytokine profiles in response to inflammatory stimulus
Archaeological Approaches to Human Remains: France
International audienceThe French scholarly landscape of human skeletal studies does not lend itself easily to general overviews due to separation of related disciplines, regionalism, and, most importantly, deep historical origins. Due to separate developmental trajectories, there is no unified discipline of "anthropology" in France, a situation that is similar to the academic organization of other European countries, including Germany and the United Kingdom. When "anthropologists," either biological or sociocultural, interact in joint projects, a development that is encouraged but not formalized, this is considered part of an interdisciplinary approach. This situation is not unique to France, but is likely an outcome of colonization of, especially, parts of Africa, which fostered the development of ethnobiologie as part of ethnology (ethnologie) that includes ethnography, a subject that developed alongside but separately from physical anthropology in the early decades of the twentieth century in France (see Conklin 2013). Paul Broca, a medical specialist in neuroanatomy, is considered the "father of physical anthropology" in France (see below). Thus biological anthropology (also l'anthropologie biologique, bioanthropologie, or anthropobiologie), formerly physical anthropology (l'anthropologie physique), has a longer association with medicine and with paleontology and prehistory (i.e., Paleolithic to Neolithic periods)-stretching well back into the nineteenth century-than with archaeology (i.e., protohistoric and historic periods). In France, prehistory sprang from paleontology (contra Cleuziou et al. 1991, who cite an origin from physical anthropology); philosophy , with its inheritance from the siècle des lumières (the "Enlightenment"); and geology, a science that deals with the "natural history of mankind." With its diverse origins, the interdisciplinary ambition of such studies today is aptly summarized o