Human response to vibration in residential environments, technical report 1 : measurement of vibration exposure

The Technical Report 1 describes the research undertaken to develop a method by which human exposure to vibration in residential environments can be assessed. That work has been carried out by the University of Salford supported by the Department of environment food and rural affairs (Defra). The overall aim of the project is to derive exposure-response relationships for human vibration in residential environments. This document in particular focuses on the equipment and methodology employed to measure vibration from different sources. The main objective of this report is to describe the practical experience of implementing a vibration measurement protocol. Reported here are findings obtained in the field measurements and a description of a feasible method for measuring vibration for different sources. In addition, controlled tests performed to determine the suitability of the vibration mounting for various practical situations are reported

HeatMapper: powerful combined visualization of gene expression profile correlations, genotypes, phenotypes and sample characteristics

BACKGROUND: Accurate interpretation of data obtained by unsupervised analysis of large scale expression profiling studies is currently frequently performed by visually combining sample-gene heatmaps and sample characteristics. This method is not optimal for comparing individual samples or groups of samples. Here, we describe an approach to visually integrate the results of unsupervised and supervised cluster analysis using a correlation plot and additional sample metadata. RESULTS: We have developed a tool called the HeatMapper that provides such visualizations in a dynamic and flexible manner and is available from . CONCLUSION: The HeatMapper allows an accessible and comprehensive visualization of the results of gene expression profiling and cluster analysis

Leptonic Production of Baryon Resonances

In these lectures, the author focuses on the electromagnetic transition between non-strange baryon states. This sector received much attention in the early 1970's after the development of the first dynamical quark models. However, experimental progress was slow, partly because of the low rates associated with electromagnetic interactions, and partly because of the lack of guidance by theoretical models that went beyond the simplest quark models. It was also difficult for experiments to achieve the precision needed for a detailed analysis of the entire resonance region in terms of the fundamental photocoupling amplitudes over a large range in momentum transfer

The Concise Guide to PHARMACOLOGY 2013/14: overview.

The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of the key properties of over 2000 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties from the IUPHAR database. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.12444/full. This compilation of the major pharmacological targets is divided into seven areas of focus: G protein-coupled receptors, ligand-gated ion channels, ion channels, catalytic receptors, nuclear hormone receptors, transporters and enzymes. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. A new landscape format has easy to use tables comparing related targets. It is a condensed version of material contemporary to late 2013, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in previous Guides to Receptors & Channels. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates

Ammonia-rich high-temperature superconducting intercalates of iron selenide revealed through time-resolved in situ x-ray and neutron diffraction

The development of a technique for following in situ the reactions of solids with alkali metal/ammonia solutions, using time-resolved X-ray diffraction methods, reveals high-temperature superconducting ammonia-rich intercalates of iron selenide which reversibly absorb and desorb ammonia around ambient temperatures.</p