Local Group dSph radio survey with ATCA (III): Constraints on Particle Dark Matter

We performed a deep search for radio synchrotron emissions induced by weakly interacting massive particles (WIMPs) annihilation or decay in six dwarf spheroidal (dSph) galaxies of the Local Group. Observations were conducted with the Australia Telescope Compact Array (ATCA) at 16 cm wavelength, with an rms sensitivity better than 0.05 mJy/beam in each field. In this work, we first discuss the uncertainties associated with the modeling of the expected signal, such as the shape of the dark matter (DM) profile and the dSph magnetic properties. We then investigate the possibility that point-sources detected in the proximity of the dSph optical center might be due to the emission from a DM cuspy profile. No evidence for an extended emission over a size of few arcmin (which is the DM halo size) has been detected. We present the associated bounds on the WIMP parameter space for different annihilation/decay final states and for different astrophysical assumptions. If the confinement of electrons and positrons in the dSph is such that the majority of their power is radiated within the dSph region, we obtain constraints on the WIMP annihilation rate which are well below the thermal value for masses up to few TeV. On the other hand, for conservative assumptions on the dSph magnetic properties, the bounds can be dramatically relaxed. We show however that, within the next 10 years and regardless of the astrophysical assumptions, it will be possible to progressively close in on the full parameter space of WIMPs by searching for radio signals in dSphs with SKA and its precursors.Comment: 17 pages, 6 figure panels. Companion papers: arXiv:1407.5479 and arXiv:1407.5482. v3: minor revision, matches published versio

Patient-Reported Outcomes Measurement Information System physical function correlates with Toronto Extremity Salvage Score in an orthopaedic oncology population

Background: The National Institute of Health\u27s Patient-Reported Outcomes Measurement Information System (PROMIS) uses computerised-adaptive testing to reduce survey burden and improve sensitivity. PROMIS is being used across medical and surgical disciplines but has not been studied in orthopaedic oncology. Questions/purposes: The aim of the study was to compare PROMIS measures with upper extremity (UE) and lower extremity (LE) Toronto Extremity Salvage Score (TESS) by assessing the following: (1) responder burden, (2) correlation between scores and (3) floor/ceiling effects. Patients and methods: This cross-sectional trial analysed all 97 adult patients treated surgically for a bone or soft tissue tumour at a tertiary institution between November 2015 and March 2016. TESS (UE or LE) and PROMIS (Physical Function, Pain Interference and Depression) surveys were administered preoperatively. Pearson correlations between each PROMIS domain and TESS were calculated, as were floor/ceiling effects of each outcome measure. Results: (1) Completion of three PROMIS questionnaires required a mean total of 16.8 (+/- 5.8 standard deviation) questions, compared with 31 and 32 questions for the LE and UE TESS questionnaires, respectively. (2) The PROMIS Physical Function scores demonstrated a strong positive correlation with the LE TESS (r = 0.84; 95% confidence interval [CI], 0.72-0.91; p \u3c 0.001) and moderate positive correlation with the UE TESS (r = 0.64; 95% CI, 0.34-0.83; p = 0.055). The PROMIS Depression scores demonstrated a weak negative correlation with both the LE TESS (r = -0.38; 95% CI, -0.61 to -0.10; p = 0.010) and with UE TESS (r = -0.38; 95% CI, -0.67 to -0.01; p = 0.055). The PROMIS Pain Interference scores demonstrated a strong negative correlation with the LE TESS (r = -0.71; 95% CI, -0.83 to -0.52; p \u3c 0.001) and a moderate negative correlation with the UE TESS (r = -0.62; 95% CI, -0.81 to -0.30; p = 0.001). (3) The UE TESS had a range of scores from 16 to 100 with a 27% ceiling effect and no floor effect, and the LE TESS had a range from 10 to 98 with no floor or ceiling effect. There was no floor or ceiling effect for any PROMIS measures. Conclusions: In an orthopaedic oncology population, the PROMIS Physical Function and Pain Interference scores correlate with the TESS and have the benefit of reduced survey burden and ceiling effect. The PROMIS Depression scores may provide additional information regarding patient outcomes not captured by the TESS. Level of Evidence: Level III. The translational potential of this article: Patient reported outcome measures asses patients\u27 symptoms, function and health-related quality of life and are designed to capture more clinical information than can be gathered by objective medial testing alone. As reimbursements and the understanding of patient outcomes are becoming tied to performance on PROMIS measures, it is an important step to establish how PROMIS measures correlate and compare to traditional legacy measures

Evidence of cross-correlation between the CMB lensing and the gamma-ray sky

We report the measurement of the angular power spectrum of cross-correlation between the unresolved component of the Fermi-LAT gamma-ray sky-maps and the CMB lensing potential map reconstructed by the Planck satellite. The matter distribution in the Universe determines the bending of light coming from the last scattering surface. At the same time, the matter density drives the growth history of astrophysical objects, including their capability at generating non-thermal phenomena, which in turn give rise to gamma-ray emissions. The Planck lensing map provides information on the integrated distribution of matter, while the integrated history of gamma-ray emitters is imprinted in the Fermi-LAT sky maps. We report here the first evidence of their correlation. We find that the multipole dependence of the cross-correlation measurement is in agreement with current models of the gamma-ray luminosity function for AGN and star forming galaxies, with a statistical evidence of 3.0$\sigma$. Moreover, its amplitude can in general be matched only assuming that these extra-galactic emitters are also the bulk contribution of the measured isotopic gamma-ray background (IGRB) intensity. This leaves little room for a big contribution from galactic sources to the IGRB measured by Fermi-LAT, pointing toward a direct evidence of the extragalactic origin of the IGRB.Comment: 6 pages, 2 figures. v2: analysis updated with Planck 2015 lensing map and 3FGL catalogue, conclusions strengthened; to appear in ApJ Letter

A Dark Matter Candidate from an Extra (Non-Universal) Dimension

We show that a recently constructed five-dimensional (5D) model with gauge-Higgs unification and explicit Lorentz symmetry breaking in the bulk, provides a natural dark matter candidate. This is the lightest Kaluza-Klein particle odd under a certain discrete Z_2 symmetry, which has been introduced to improve the naturalness of the model, and resembles KK-parity but is less constraining. The dark matter candidate is the first KK mode of a 5D gauge field and electroweak bounds force its mass above the TeV scale. Its pair annihilation rate is too small to guarantee the correct relic abundance; however coannihilations with colored particles greatly enhance the effective annihilation rate, leading to realistic relic densities.Comment: 26 pages, 10 figures; v2: fig.1 corrected, one reference and some comments added, conclusions unchanged. Version to appear in JHE

Safety of overlapping inpatient orthopaedic surgery: A multicenter study

BackgroundAlthough overlapping surgery is used to maximize efficiency, more empirical data are needed to guide patient safety. We conducted a retrospective cohort study to evaluate the safety of overlapping inpatient orthopaedic surgery, as judged by the occurrence of perioperative complications.MethodsAll inpatient orthopaedic surgical procedures performed at 5 academic institutions from January 1, 2015, to December 31, 2015, were included. Overlapping surgery was defined as 2 skin incisions open simultaneously for 1 surgeon. In comparing patients who underwent overlapping surgery with those who underwent non-overlapping surgery, the primary outcome was the occurrence of a perioperative complication within 30 days of the surgical procedure, and secondary outcomes included all-cause 30-day readmission, length of stay, and mortality. To determine if there was an association between overlapping surgery and a perioperative complication, we tested for non-inferiority of overlapping surgery, assuming a null hypothesis of an increased risk of 50%. We used an inverse probability of treatment weighted regression model adjusted for institution, procedure type, demographic characteristics (age, sex, race, comorbidities), admission type, admission severity of illness, and clustering by surgeon.ResultsAmong 14,135 cases, the frequency of overlapping surgery was 40%. The frequencies of perioperative complications were 1% in the overlapping surgery group and 2% in the non-overlapping surgery group. The overlapping surgery group was non-inferior to the non-overlapping surgery group (odds ratio [OR], 0.61 [90% confidence interval (CI), 0.45 to 0.83]; p < 0.001), with reduced odds of perioperative complications (OR, 0.61 [95% CI, 0.43 to 0.88]; p = 0.009). For secondary outcomes, there was a significantly lower chance of all-cause 30-day readmission in the overlapping surgery group (OR, 0.67 [95% CI, 0.52 to 0.87]; p = 0.003) and shorter length of stay (e, 0.94 [95% CI, 0.89 to 0.99]; p = 0.012). There was no difference in mortality.ConclusionsOur results suggest that overlapping inpatient orthopaedic surgery does not introduce additional perioperative risk for the complications that we evaluated. The suitability of this practice should be determined by individual surgeons on a case-by-case basis with appropriate informed consent.Level of evidenceTherapeutic Level III. See Instructions for Authors for a complete description of levels of evidence

VLBA determination of the distance to nearby star-forming regions I. The distance to T Tauri with 0.4% accuracy

In this article, we present the results of a series of twelve 3.6-cm radio continuum observations of T Tau Sb, one of the companions of the famous young stellar object T Tauri. The data were collected roughly every two months between September 2003 and July 2005 with the Very Long Baseline Array (VLBA). Thanks to the remarkably accurate astrometry delivered by the VLBA, the absolute position of T Tau Sb could be measured with a precision typically better than about 100 micro-arcseconds at each of the twelve observed epochs. The trajectory of T Tau Sb on the plane of the sky could, therefore, be traced very precisely, and modeled as the superposition of the trigonometric parallax of the source and an accelerated proper motion. The best fit yields a distance to T Tau Sb of 147.6 +/- 0.6 pc. The observed positions of T Tau Sb are in good agreement with recent infrared measurements, but seem to favor a somewhat longer orbital period than that recently reported by Duchene et al. (2006) for the T Tau Sa/T Tau Sb system.Comment: 24 pages, 3 pages, AASTEX format, accepted for publication in Ap

ILPF como alternativa para diminuição do uso do fogo.

Há uma demanda crescente por informações sobre tecnologias agropecuárias que melhorem a produtividade, agreguem valor aos produtos, diminuam ou mesmo evitem o uso do fogo. O manejo do fogo de forma inadequada tem levado à perda de grandes áreas de floresta e outras coberturas vegetais, gerando importantes problemas ambientais, econômicos e sociais, como a diminuição da qualidade do ar, a perda de plantios e de áreas com alta diversidade biológica, degradação do solo e declínio da produtividade agrícola.bitstream/item/151569/1/ILPF.pd