Smart Specialisation Strategies for Supporting Europe 2020 Vision. Looking at the American Experience: the Case of the Boston Area

These reflections aim to highlight the crucial challenge that European Regions are called to face applying the ‘Research and Innovation Strategies for Smart Specialization’ policy for pursuing the virtuous implementation of EU Cohesion Policy and ‘Europe 2020’ Agenda. The original cultural style of the ‘US Smart Specialization model’, supported by the ‘cluster theory’ and the ‘innovation paradigm’, represents a significant lesson in Boston area

One-Dimensional Super Calabi-Yau Manifolds and their Mirrors

We apply a definition of generalised super Calabi-Yau variety (SCY) to supermanifolds of complex dimension one. One of our results is that there are two SCY's having reduced manifold equal to $\mathbb{P}^1$, namely the projective super space $\mathbb{P}^{1|2}$ and the weighted projective super space $\mathbb{WP}^{1|1}_{(2)}$. Then we compute the corresponding sheaf cohomology of superforms, showing that the cohomology with picture number one is infinite dimensional, while the de Rham cohomology, which is what matters from a physical point of view, remains finite dimensional. Moreover, we provide the complete real and holomorphic de Rham cohomology for generic projective super spaces $\mathbb P^{n|m}$. We also determine the automorphism groups: these always match the dimension of the projective super group with the only exception of $\mathbb{P}^{1|2}$, whose automorphism group turns out to be larger than the projective general linear supergroup. By considering the cohomology of the super tangent sheaf, we compute the deformations of $\mathbb{P}^{1|m}$, discovering that the presence of a fermionic structure allows for deformations even if the reduced manifold is rigid. Finally, we show that $\mathbb{P}^{1|2}$ is self-mirror, whereas $\mathbb{WP} ^{1|1}_{(2)}$ has a zero dimensional mirror. Also, the mirror map for $\mathbb{P}^{1|2}$ naturally endows it with a structure of $N=2$ super Riemann surface.Comment: 50 pages. Accepted for publication in JHE

Hardware design of LIF with Latency neuron model with memristive STDP synapses

In this paper, the hardware implementation of a neuromorphic system is presented. This system is composed of a Leaky Integrate-and-Fire with Latency (LIFL) neuron and a Spike-Timing Dependent Plasticity (STDP) synapse. LIFL neuron model allows to encode more information than the common Integrate-and-Fire models, typically considered for neuromorphic implementations. In our system LIFL neuron is implemented using CMOS circuits while memristor is used for the implementation of the STDP synapse. A description of the entire circuit is provided. Finally, the capabilities of the proposed architecture have been evaluated by simulating a motif composed of three neurons and two synapses. The simulation results confirm the validity of the proposed system and its suitability for the design of more complex spiking neural network

NLO Higgs boson production via gluon fusion matched with shower in POWHEG

We present a next-to-leading order calculation of Higgs boson production via gluon fusion interfaced to shower Monte Carlo programs, implemented according to the POWHEG method. A detailed comparison with MC@NLO and PYTHIA is carried out for several observables, for the Tevatron and LHC colliders. Comparisons with next-to-next-to-leading order results and with resummed ones are also presented.Comment: Version accepted for publication by JHEP. One more figure added to Sec 4.1.2 and two more explanatory figures and comments added to Sec 4.3 on p_T distribution

Hardware prototyping and validation of a W-ΔDOR digital signal processor

Microwave tracking, usually performed by on ground processing of the signals coming from a spacecraft, represents a crucial aspect in every deep-space mission. Various noise sources, including receiver noise, affect these signals, limiting the accuracy of the radiometric measurements obtained from the radio link. There are several methods used for spacecraft tracking, including the Delta-Differential One-Way Ranging (ΔDOR) technique. In the past years, European Space Agency (ESA) missions relied on a narrowband ΔDOR system for navigation in the cruise phase. To limit the adverse effect of nonlinearities in the receiving chain, an innovative wideband approach to ΔDOR measurements has recently been proposed. This work presents the hardware implementation of a new version of the ESA X/Ka Deep Space Transponder based on the new tracking technique named Wideband ΔDOR (W-ΔDOR). The architecture of the new transponder guarantees backward compatibility with narrowband ΔDOR

Structure formation in active networks

Structure formation and constant reorganization of the actin cytoskeleton are key requirements for the function of living cells. Here we show that a minimal reconstituted system consisting of actin filaments, crosslinking molecules and molecular-motor filaments exhibits a generic mechanism of structure formation, characterized by a broad distribution of cluster sizes. We demonstrate that the growth of the structures depends on the intricate balance between crosslinker-induced stabilization and simultaneous destabilization by molecular motors, a mechanism analogous to nucleation and growth in passive systems. We also show that the intricate interplay between force generation, coarsening and connectivity is responsible for the highly dynamic process of structure formation in this heterogeneous active gel, and that these competing mechanisms result in anomalous transport, reminiscent of intracellular dynamics

A Note on Super Koszul Complex and the Berezinian

We construct the super Koszul complex of a free supercommutative $A$-module $V$ of rank $p|q$ and prove that its homology is concentrated in a single degree and it yields an exact resolution of $A$. We then study the dual of the super Koszul complex and show that its homology is concentrated in a single degree as well and isomorphic to $\Pi^{p+q} A$, with $\Pi$ the parity changing functor. Finally, we show that, given an automorphism of $V$, the induced transformation on the only non-trivial homology class of the dual of the super Koszul complex is given by the multiplication by the Berezinian of the automorphism, thus relating this homology group with the Berezinian module of $V$.Comment: 13 pages, reference adde

Iron Status and Analysis of Efficacy and Safety of Ferric Carboxymaltose Treatment in Patients with Inflammatory Bowel Disease

Background and Aims:We analyzed iron deficiency and the therapeutic response following intravenous ferric carboxymaltose in a large single-center inflammatory bowel disease (IBD) cohort. Methods: 250 IBD patients were retrospectively analyzed for iron deficiency and iron deficiency anemia. A subgroup was analyzed regarding efficacy and side effects of iron supplementation with ferric carboxymaltose. Results: In the cohort (n = 250), 54.4% of the patients had serum iron levels 60 mu g/dl, 61.6% had ferritin >100 ng/ml, and 90.7% reached Hb >12/13 g/dl at follow-up (p < 0.0001 for all parameters vs. pretreatment values). The most frequent adverse event was a transient increase of liver enzymes with male gender as risk factor (p = 0.008, OR 8.62, 95% CI 1.74-41.66). Conclusions: Iron deficiency and anemia are frequent in IBD patients. Treatment with ferric carboxymaltose is efficious, safe and well tolerated in iron-deficient IBD patients. Copyright (C) 2011 S. Karger AG, Base