Sensitivity of North American monsoon rainfall to multisource sea surface temperatures in MM5

In this article, four continually processed sea surface temperature (SST) datasets, including the Reynolds SST (RYD), the global final analysis of skin temperature at oceans (FNL), and two Moderate Resolution Imaging Spectroradiometer (MODIS) Aqua SSTs retrieved from thermal infrared imagery (TIR) and midinfrared imagery (MIR), were compared. The results show variations from each other. In comparison with the RYD SST, the FNL data have -0.5° ∼ 0.5°C perturbations, while the TIR and MIR SSTs possess larger deviations of -2° ∼ 1°C, mainly due to algorithm and/or sensor differences in these SST datasets. A regional model, the fifth-generation Pennsylvania State University-Na tional Center for Atmospheric Research (Penn State-NCAR) Mesoscale Model (MM5), was used to investigate whether model atmospheric predictions, especially those concerning precipitation during the North American monsoon season, are sensitive to these SST variations. A comparison of rainfall, atmospheric height, temperature, and wind fields produced by model results, reanalysis data, and observations indicates that, at monthly scale, the model shows changes in the simulations for three consecutive years; in particular, rainfall amounts, timing, and even patterns vary at some specific regions. Forced by the MODIS Aqua midinfrared SST (MIR), which includes large regions with SST values lower than the conventional Reynolds SST, the MM5 rain field predictions show reduced errors over land and oceans compared to when the model is forced by other SST data. Specifically, rainfall estimates are improved over the offshore of southern Mexico, the Gulf of Mexico, the coastal regions of southern and eastern Mexico, and the southwestern U.S. monsoon active region, but only slightly improved over the monsoon core and the high-elevated Great Plains. Using MIR SST data, one is also capable of improving geopotential height and temperature fields in comparison wit he reanalysis data. © 2005 American Meteorological Society

VirtualHome: Simulating Household Activities via Programs

In this paper, we are interested in modeling complex activities that occur in a typical household. We propose to use programs, i.e., sequences of atomic actions and interactions, as a high level representation of complex tasks. Programs are interesting because they provide a non-ambiguous representation of a task, and allow agents to execute them. However, nowadays, there is no database providing this type of information. Towards this goal, we first crowd-source programs for a variety of activities that happen in people's homes, via a game-like interface used for teaching kids how to code. Using the collected dataset, we show how we can learn to extract programs directly from natural language descriptions or from videos. We then implement the most common atomic (inter)actions in the Unity3D game engine, and use our programs to "drive" an artificial agent to execute tasks in a simulated household environment. Our VirtualHome simulator allows us to create a large activity video dataset with rich ground-truth, enabling training and testing of video understanding models. We further showcase examples of our agent performing tasks in our VirtualHome based on language descriptions.Comment: CVPR 2018 (Oral

Experimental observation of chiral phonons in monolayer WSe2

Chirality characterizes an object that is not identical to its mirror image. In condensed matter physics, Fermions have been demonstrated to obtain chirality through structural and time-reversal symmetry breaking. These systems display unconventional electronic transport phenomena such as the quantum Hall effect and Weyl semimetals. However, for bosonic collective excitations in atomic lattices, chirality was only theoretically predicted and has never been observed. We experimentally show that phonons can exhibit intrinsic chirality in monolayer tungsten diselenide, whose lattice breaks the inversion symmetry and enables inequivalent electronic K and -K valley states. The time-reversal symmetry is also broken when we selectively excite the valley polarized holes by circularly polarized light. Brillouin-zone-boundary phonons are then optically created by the indirect infrared absorption through the hole-phonon interactions. The unidirectional intervalley transfer of holes ensures that only the phonon modes in one valley are excited. We found that such photons are chiral through the transient infrared circular dichroism, which proves the valley phonons responsible to the indirect absorption has non-zero pseudo-angular momentum. From the spectrum we further deduce the energy transferred to the phonons that agrees with both the first principle calculation and the double-resonance Raman spectroscopy. The chiral phonons have significant implications for electron-phonon coupling in solids, lattice-driven topological states, and energy efficient information processing

Sarco/Endoplasmic Reticulum Ca-ATPase (SERCA) pump is a more effective Calcium-handling mediator than the Sodium-Calcium Exchanger (NCX) in hESC-derived ventricular cardiomyocytes

Poster Session - Heart Regeneration: no. 29DMM 2011 entitled: Re-engineering Regenerative MedicineVentricular (V) cardiomyocytes (CMs) are non-regenerative. Self-renewable pluripotent human embryonic stem cells (hESCs) can differentiate into CMs for cellbased therapies. We have previously shown that hESC-derived CMs display immature Ca-handling properties, with smaller transient amplitudes and slower upstroke and decay kinetics. These functional immaturities can be attributed to their proteomic differences in crucial Ca-handling proteins such as the complete absence of triadin, junctin, CSQ, phospholamban. Indeed, forced CSQ expression partially …postprin

Translational potential of human embryonic and induced pluripotent stem cells for myocardial repair: Insights from experimental models

Heart diseases have been a major cause of death worldwide, including developed countries. Indeed, loss of non-regenerative, terminally differentiated cardiomyocytes (CMs) due to aging or diseases is irreversible. Current therapeutic regimes are palliative in nature, and in the case of end-stage heart failure, transplantation remains the last resort. However, this option is significantly hampered by a severe shortage of donor cells and organs. Human embryonic stem cells (hESCs) can self-renew while maintaining their pluripotency to differentiate into all cell types. More recently, direct reprogramming of adult somatic cells to become pluripotent hES-like cells (a.k.a. induced pluripotent stem cells or iPSCs) has been achieved. The availability of hESCs and iPSCs, and their successful differentiation into genuine human heart cells have enabled researchers to gain novel insights into the early development of the human heart as well as to pursue the revolutionary paradigm of heart regeneration. Here we review our current knowledge of hESC-/iPSC-derived CMs in the context of two fundamental operating principles of CMs (i.e. electrophysiology and Ca2+-handling), the resultant limitations and potential solutions in relation to their translation into clinical (bioartificial pacemaker, myocardial repair) and other applications (e.g. as models for human heart disease and cardiotoxicity screening). © Schattauer 2010.published_or_final_versio

Developmental cues for the maturation of metabolic, electrophysiological and calcium handling properties of human pluripotent stem cell-derived cardiomyocytes

Human pluripotent stem cells (hPSCs), including embryonic and induced pluripotent stem cells, are abundant sources of cardiomyocytes (CMs) for cell replacement therapy and other applications such as disease modeling, drug discovery and cardiotoxicity screening. However, hPSC-derived CMs display immature structural, electrophysiological, calcium-handling and metabolic properties. Here, we review various biological as well as physical and topographical cues that are known to associate with the development of native CMs in vivo to gain insights into the development of strategies for facilitated maturation of hPSC-CMs. © 2014 Keung et al.; licensee BioMed Central Ltd.published_or_final_versio

Ferrate(VI) oxidation of endocrine disruptors and antimicrobials in water

Author name used in this publication: X. Z. LiAccepted ManuscriptPublishe

ATM-based TH-SSMA network for multimedia PCS

Personal communications services (PCS) promise to provide a variety of information exchanges among users with any type of mobility, at any time, in any place, through any available device. To achieve this ambitious goal, two of the major challenges in the system design are: i) to provide a high-speed wireless subsystem with large capacity and acceptable quality-of-service (QoS) and ii) to design a network architecture capable of supporting multimedia traffic and various kinds of user mobility. A time-hopping spread-spectrum wireless communication system called ultra-wide bandwidth (UWB) radio is used to provide communications that are low power, high data rate, fade resistant, and relatively shadow free in a dense multipath environment. Receiver-signal processing of UWB radio is described, and performance of such communications systems, in terms of multiple-access capability, is estimated under ideal multiple-access channel conditions. A UWB-signal propagation experiment is performed using the bandwidth in excess of 1 GHz in a typical modern office building in order to characterize the UWB-signal propagation channel. The experimental results demonstrate the feasibility of the UWB radio and its robustness in a dense multipath environment. In this paper, an ATM network is used as the backbone network due to its high bandwidth, fast switching capability, flexibility, and well-developed infrastructure. To minimize the impact caused by user mobility on the system performance, a hierarchical network-control architecture is postulated. A wireless virtual circuit (WVC) concept is proposed to improve the transmission efficiency and simplify the network control in the wireless subsystem. The key advantage of this network architecture and WVC concept is that the handoff can be done locally most of the time, due to the localized behavior of PCS users.published_or_final_versio