30 research outputs found

    Transient acantholytic dermatosis

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    GoalDAG – ArchiMate Integration

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    Organizational alignment is an important issue in various interest areas such as Strategy, Business Process Management, Requirements Engineering, and Enterprise Architecture. From IT perspective the most holistic approach on alignment and control is Enterprise Architecture. Enterprise Architecture's eminent standard framework is TOGAF with companion architecture modeling language ArchiMate. Although ArchiMate proposes Motivation Extension to facilitate strategic alignment, this extension does not offer any facility to verify and/or validate the architecture model. Moreover, the Motivation Extension proposes its model elements to be linked to the core elements only through the stakeholder element. This paper proposes an ArchiMate Profile for GoalDAG. GoalDAG is a simple goal model that can be linked to the different model elements seamlessly and enables to validate the existing model. To represent GoalDAG integration with Enterprise Architecture, ArchiMate GoalDAG profile is developed and exemplified through TOGAF's ArchiSurance fictitious case study

    Sedentary behavior and blood pressure control among osteoarthritis initiative participants

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    SummaryObjectiveTo examine the association between sedentary behavior and blood pressure (BP) among Osteoarthritis Initiative (OAI) participants.DesignWe conducted a cross-sectional analysis of the OAI 48-month visit participants whose physical activity was measured using accelerometers. Participants were classified into four quartiles according to the percentage of wear time that was sedentary (<100 activity counts per min). Users of antihypertensive medications or non-steroidal anti-inflammatory drugs (NSAIDs) were excluded. Our main outcomes were systolic and diastolic blood pressures (SBP and DBP) and “elevated BP” defined as BP ≥ 130/85 mm Hg.ResultsFor this study cohort (N = 707), mean BP was 121.4 ± 15.6/74.7 ± 9.5 mm Hg and 33% had elevated BP. SBP had a graded association with increased sedentary time (P for trend = 0.02). The most sedentary quartile had 4.26 mm Hg higher SBP (95% confidence interval (CI), 0.69–7.82; P = 0.02) than the least sedentary quartile, adjusting for age, moderate-to-vigorous (MV) physical activity, and other demographic and health factors. The probability of having elevated BP significantly increased in higher sedentary quartiles (P for trend = 0.046). There were no significant findings for DBP.ConclusionA strong graded association was demonstrated between sedentary behavior and increased SBP and elevated BP, independent of time spent in MV physical activity. Reducing daily sedentary time may lead to improvement in BP and reduction in cardiovascular risk
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