Surface effects in preparation of cell-size liposomes

AbstractEffects of surface type and area were shown to be important in the yield of cell-size liposomes, but not in determining their size. The liposomes were prepared by dissolving lipids in a chloroform-methanol solution and then evaporating the solvent under nitrogen in the presence of glass beads. After evaporation of the solvent, which was rapid due to the increased surface area, the dried lipids were then swollen in water at high temperatures (higher than the phase transition of the lipids), which led to formation of giant liposomes. The number of liposomes prepared in the presence of pyrex glass beads, which increase more than 100-times the surface area of lipid-glass contact, is more than 5-times larger than in the control experiments without glass beads. The yield of liposomes in the presence of another type of glass bead was almost the same as in the control experiments. These effects may be due to long- and short-range intermolecular interactions in the glass/water/lipid system

Spin-dependent structure functions g^1\hat g_1 and g^2\hat g_2 for inclusive spin-half baryon production in electron-positron annihilation

Two spin-dependent structure functions $\hat g_1$ and $\hat g_2$ for the inclusive spin-half baryon production in electron-positron annihilation are studied in the context of QCD factorization as well as in the naive quark parton model. As a result, it is found that the sum of $\hat g_1$ and $\hat g_2$ is related to $\hat h_1$ and $\hat g_T$, two quark fragmentation functions defined by Jaffe and Ji. In connection with the measurement of quark fragmentation functions, the possible phenomenological consequences are discussed.Comment: RevTex, four Ps figures, to appear in Phys. Rev.

Simplifying the mosaic description of DNA sequences

By using the Jensen-Shannon divergence, genomic DNA can be divided into compositionally distinct domains through a standard recursive segmentation procedure. Each domain, while significantly different from its neighbours, may however share compositional similarity with one or more distant (non--neighbouring) domains. We thus obtain a coarse--grained description of the given DNA string in terms of a smaller set of distinct domain labels. This yields a minimal domain description of a given DNA sequence, significantly reducing its organizational complexity. This procedure gives a new means of evaluating genomic complexity as one examines organisms ranging from bacteria to human. The mosaic organization of DNA sequences could have originated from the insertion of fragments of one genome (the parasite) inside another (the host), and we present numerical experiments that are suggestive of this scenario.Comment: 16 pages, 1 figure, Accepted for publication in Phys. Rev.

Low electric field induction in BaTiO3-epoxy nanocomposites

Epoxy is widely used material, but epoxy has limitations in terms of brittleness in failure, and thus researchers explore toughening and strengthening options such as adding a second phase or using electromagnetic fields to tailor toughness and strength, on demand and nearly instantaneously. Such approach falls into the category of active toughening but has not been extensively investigated. In this research, Si-BaTiO3 nanoparticles were used to modify the electro-mechanical properties of a high-performance aerospace-grade epoxy so as to study its response to electric fields, specifically low field strengths. To promote uniform dispersion and distribution, the Si-BaTiO3 nanoparticles were functionalised with silane coupling agents and mixed in the epoxy Araldite LY1564 at different content loads (1, 5, 10 wt%), which was then associated with its curing agent Aradur 3487. Real-time measurements were conducted using Raman spectroscopy while applying electric fields to the nanocomposite specimens. The Raman data showed a consistent trend of increasing intensity and peak broadening under the increasing electric field strength and Si-BaTiO3 contents. This was attributed to the BaTiO3 particles’ dipolar displacement in the high-content nanocomposites (i.e., 5 wt% and 10 wt%). The study offers valuable insights on how electric field stimulation can actively enhance the mechanical properties in epoxy composites, specifically in relatively low fields and thin, high-aspect-ratio composite layers which would require in-situ mechanical testing equipped with electric field application, an ongoing investigation of the current research

Communication and optimal hierarchical networks

We study a general and simple model for communication processes. In the model, agents in a network (in particular, an organization) interchange information packets following simple rules that take into account the limited capability of the agents to deal with packets and the cost associated to the existence of open communication channels. Due to the limitation in the capability, the network collapses under certain conditions. We focus on when the collapse occurs for hierarchical networks and also on the influence of the flatness or steepness of the structure. We find that the need for hierarchy is related to the existence of costly connections.Comment: 7 pages, 2 figures. NATO ARW on Econophysic

Resolution studies of cosmic-ray tracks in a TPC with GEM readout

A large volume TPC is a leading candidate for the central tracking detector at a future high energy linear collider. To improve the resolution a new readout based on micro-pattern gas detectors is being developed. Measurements of the spatial resolution of cosmic-ray tracks in a GEM TPC are presented. We find that the resolution suffers if the readout pads are too wide with respect to the charge distribution at the readout plane due to insufficient charge sharing. For narrow pads of 2 x 6 mm**2 we measure a resolution of 100 micometer at short drift distances in the absence of an axial magnetic field. The dependence of the spatial resolution as a function of drift distance allows the determination of the underlying electron statistics. Our results show that the present technique uses about half the statistical power available from the number of primary electrons. The track angle effect is observed as expected.Comment: 18 pages, 8 figures, version as published in Nucl. Inst. Met

Rapidity distribution as a probe for elliptical flow at intermediate energies

Interplay between the spectator and participant matter in heavy-ion collisions is investigated within isospin dependent quantum molecular dynamics (IQMD) model in term of rapidity distribution of light charged particles. The effect of different types and size rapidity distributions is studied in elliptical flow. The elliptical flow patterns show important role of the nearby spectator matter on the participant zone. This role is further explained on the basis of passing time of the spectator and expansion time of the participant zone. The transition from the in-plane to out-of-plane is observed only when the mid-rapidity region is included in the rapidity bin, otherwise no transition occurs. The transition energy is found to be highly sensitive towards the size of the rapidity bin, while weakly on the type of the rapidity distribution. The theoretical results are also compared with the experimental findings and are found in good agreement.Comment: 8 figure

Profiling Occupant Behaviour in Danish Dwellings using Time Use Survey Data - Part I: Data Description and Activity Profiling

The human interaction with the building is a key cause of uncertainty when predicting energy consump- tion of buildings. Building occupants affect building energy use directly and indirectly by interacting with building energy systems, for example, by adjusting thermostats, switching lights on/off, using electri- cal devices and opening/closing windows. The occupants’ daily activity profiles and occupancy patterns clearly shape the timing and magnitude of energy demand in households. Modelling energy-related hu- man activities throughout the day, therefore, is a crucial task for prediction of energy use and, conse- quently, to reduce the gap between real and predicted building energy use. This study modelled data gathered in the diary-based Danish Time Use Survey (TUS) 2008/09 of 9640 individuals from 4679 households. Individuals’ daily activities were logged in 10-min time increments for 24 h, starting and ending at 04:00, during both weekdays and weekends. The aims of this study were to (i) profile energy-related daily activities of occupants during different seasons and weekdays/weekends (ii) investigate time-related characteristics of activities such as starting and ending times and durations, and (iii) profile occupancy patterns for weekdays/weekends for different household types. The outcomes provide valuable input for building energy simulation for bridging the gap between simulated and real energy consumption in the Danish residential sector; typical occupancy profiles for different household types for different days of the week are freely available online[1]

Depth Evaluation of Soft Tissue Mimicking Phantoms Using Surface Acoustic Waves

AbstractSurface acoustic wave (SAW) shows advantages in revealing skin mechanical properties. In this paper, we evaluates the elasticity of tissue mimicking phantoms by inversion of SAWs phase velocity to Young's Modulus, the estimated SAWs evaluating depth is determined based on the assumption of that SAWs penetration approximately equals one wavelength. The tissue mimicking phantoms are made of agar with concentration of 1%, 2% and 3%. Their elasticity tested from our system is 13.3kPa, 53.4kPa and 257.9kPa respectively, with expected gradient. The evaluation depth is then estimated as 0.542mm to 3.403mm underneath the phantom surface, which indicates that this method is suitable to measure elasticity in dermis layer of skin