Diffuse somatostatin-immunoreactive D-cell hyperplasia in the stomach and duodenum

This paper presents the first case of extensive, diffuse, somatostatin- immunoreactive D-cell hyperplasia in the human stomach and duodenum. It occurred in a 37-yr-old woman, who showed clinical signs of dwarfism, obesity, dryness of the mouth, and goiter. The density of the distribution of D cells was increased 39-fold in the stomach fundus, 23- fold in the proximal antrum, 25-fold in the distal antrum, and 31-fold in the upper duodenum in comparison with normal values. At the same time, the gastrin-immunoreactive cells were increased 2.3-fold in the antrum. Although the range in size of the D cells was within normal limits in all regions examined, the G cells showed pronounced hypertrophy of up to 127%. A possible relationship between the immuno- histochemical findings and the clinical picture is discussed

Graphene microwave transistors on sapphire substrates

We have developed metal-oxide graphene field-effect transistors (MOGFETs) on sapphire substrates working at microwave frequencies. For monolayers, we obtain a transit frequency up to ~ 80 GHz for a gate length of 200 nm, and a power gain maximum frequency of about ~ 3 GHz for this specific sample. Given the strongly reduced charge noise for nanostructures on sapphire, the high stability and high performance of this material at low temperature, our MOGFETs on sapphire are well suited for a cryogenic broadband low-noise amplifier

Spartan Daily, January 6, 1950

Volume 38, Issue 53https://scholarworks.sjsu.edu/spartandaily/11319/thumbnail.jp

Shot noise and conductivity at high bias in bilayer graphene: Signatures of electron-optical phonon coupling

We have studied electronic conductivity and shot noise of bilayer graphene (BLG) sheets at high bias voltages and low bath temperature $T_0=4.2$ K. As a function of bias, we find initially an increase of the differential conductivity, which we attribute to self-heating. At higher bias, the conductivity saturates and even decreases due to backscattering from optical phonons. The electron-phonon interactions are also responsible for the decay of the Fano factor at bias voltages $V>0.1$ V. The high bias electronic temperature has been calculated from shot noise measurements, and it goes up to $\sim1200$ K at $V=0.75$ V. Using the theoretical temperature dependence of BLG conductivity, we extract an effective electron-optical phonon scattering time $\tau_{e-op}$. In a 230 nm long BLG sample of mobility $\mu=3600$ cm$^2$V$^{-1}$s$^{-1}$, we find that $\tau_{e-op}$ decreases with increasing voltage and is close to the charged impurity scattering time $\tau_{imp}=60$ fs at $V=0.6$ V.Comment: 7 pages, 7 figures. Extended version of the high bias part of version 1. The low bias part is discussed in arXiv:1102.065

Structure and stability of chiral beta-tapes: a computational coarse-grained approach

We present two coarse-grained models of different levels of detail for the description of beta-sheet tapes obtained from equilibrium self-assembly of short rationally designed oligopeptides in solution. Here we only consider the case of the homopolymer oligopeptides with the identical sidegroups attached, in which the tapes have a helicoid surface with two equivalent sides. The influence of the chirality parameter on the geometrical characteristics, namely the diameter, inter-strand distance and pitch, of the tapes have been investigated. The two models are found to produceequivalent results suggesting a considerable degree of universality in conformations of the tapes.Comment: 24 pages, 5 PS figures. Accepted to J. Chem. Phy

Facilitating Humanitarian Access to Pharmaceutical and Agricultural Innovation

Calls for intellectual property licensing strategies in the pharmaceutical and agricultural sectors that promote humanitarian access to product innovations for the benefit of the disadvantaged. Includes profiles of successful and promising strategies

Time as a limited resource: Communication Strategy in Mobile Phone Networks

We used a large database of 9 billion calls from 20 million mobile users to examine the relationships between aggregated time spent on the phone, personal network size, tie strength and the way in which users distributed their limited time across their network (disparity). Compared to those with smaller networks, those with large networks did not devote proportionally more time to communication and had on average weaker ties (as measured by time spent communicating). Further, there were not substantially different levels of disparity between individuals, in that mobile users tend to distribute their time very unevenly across their network, with a large proportion of calls going to a small number of individuals. Together, these results suggest that there are time constraints which limit tie strength in large personal networks, and that even high levels of mobile communication do not fundamentally alter the disparity of time allocation across networks.Comment: 10 pages, 3 figures. Accepted for publication in Social Network

Spartan Daily, November 1, 1960

Volume 48, Issue 25https://scholarworks.sjsu.edu/spartandaily/4079/thumbnail.jp