Revisiting network neutrality

The paper discusses the topical subject of network neutrality, from a US and European legal perspective. The article will begin by first defining network neutrality before addressing the underpinning technology and will then compare the legal approaches adopted by Europe and the US. In Europe, there is an existing electronic communications regulatory framework which can be used to address the network neutrality problem rendering any further legislation unnecessary and perhaps, detrimental to the current framework. In the US, however, the main concern arising is a potential for a 'fragmented' internet, which leads to our conclusion that network neutrality legislation is necessary on multiple levels. The article will conclude that the US' stance on network neutrality legislation will cause a seismic shift in the way we view technology and the way that networks are accessed and utilised

Data protection: the challenges facing social networking

The popularity of social networking sites has increased dramatically over the past decade. A recent report indicated that thirty-eight percent of online users have a social networking profile. Many of these social networking site users (SNS users) post or provide personal information over the internet every day. According to the latest OfCom study, the average adult SNS user has profiles on 1.6 sites and most check their profiles at least once every other day. However, the recent rise in social networking activity has opened the door to the misuse and abuse of personal information through identity theft, cyber stalking, and undesirable screenings by prospective employers. Behavioral advertising programs have also misused personal information available on social networking sites. Society is now facing an important question: what level of privacy should be expected and required within the social networking environment

Carbon isotope anomaly in the major plant C-1 pool and its global biogeochemical implications

We report that the most abundant C-1 units of terrestrial plants, the methoxyl groups of pectin and lignin, have a unique carbon isotope signature exceptionally depleted in C-13. Plant-derived C-1 volatile organic compounds (VOCs) are also anomalously depleted in C-13 compared with Cn+1 VOCs. The results confirm that the plant methoxyl pool is the predominant source of biospheric C-1 compounds of plant origin such as methanol, chloromethane and bromomethane. Furthermore this pool, comprising ca 2.5% of carbon in plant biomass, could be an important substrate for methanogenesis and thus be envisaged as a possible source of isotopically light methane entering the atmosphere. Our findings have significant implications for the use of carbon isotope ratios in elucidation of global carbon cycling. Moreover methoxyl groups could act as markers for biological activity in organic matter of terrestrial and extraterrestrial origin

COMPLEMENT-MEDIATED ADIPOCYTE LYSIS BY NEPHRITIC FACTOR SERA

Recent data indicate a previously unsuspected link between the complement system and adipocyte biology. Murine adipocytes produce key components of the alternative pathway of complement and are able to activate this pathway. This suggested to us an explanation for adipose tissue loss in partial lipodystrophy, a rare human condition usually associated with the immunoglobulin G(IgG) autoantibody nephritic factor (NeF) which leads to enhanced alternative pathway activation in vivo. We hypothesized that in the presence of NeF, there is dysregulated complement activation at the membrane of the adipocyte, leading to adipocyte lysis. Here we show that adipocytes explanted from rat epididymal fat pads are lysed by NeF-containing sera but not by control sera. A similar pattern is seen with IgG fractions of these sera. Adipocyte lysis in the presence of NeF is associated with the generation of fluid-phase terminal complement complexes, the level of which correlates closely with the level of lactate dehydrogenase, a marker of cell lysis. Lysis is abolished by ethylenediaminetetraacetic acid, which chelates divalent cations and prevents complement activation, and reduced by an antibody to factor D, a key component of the alternative pathway. These data provide an explanation for the previously obscure link between NeF and fat cell damage

WebML+ in a nutshell: Modeling architectural-level information flows

One aspect of the development of Web-enabled systems that has received increasing attention is information modeling, particularly with respect to aspects such as navigation models and their relationships to the underlying content. These models have, however, typically focused on modeling at a relatively low-level and have failed to address higher-level aspects, such as architectural and even business process modeling. In this paper we introduce a set of formal extensions to an existing modeling language - WebML - that facilitates information modeling at this higher level of abstraction. We argue that these extensions will provide a clearer connection between an understanding of business models and processes, and the lower-level designs typically represented in existing models