2,449 research outputs found
Diffractive Optics for Gravitational Wave Detectors
All-reflective interferometry based on nano-structured diffraction gratings
offers new possibilities for gravitational wave detection. We investigate an
all-reflective Fabry-Perot interferometer concept in 2nd order Littrow mount.
The input-output relations for such a resonator are derived treating the
grating coupler by means of a scattering matrix formalism. A low loss
dielectric reflection grating has been designed and manufactured to test the
properties of such a grating cavity
Billiard Systems in Three Dimensions: The Boundary Integral Equation and the Trace Formula
We derive semiclassical contributions of periodic orbits from a boundary
integral equation for three-dimensional billiard systems. We use an iterative
method that keeps track of the composition of the stability matrix and the
Maslov index as an orbit is traversed. Results are given for isolated periodic
orbits and rotationally invariant families of periodic orbits in axially
symmetric billiard systems. A practical method for determining the stability
matrix and the Maslov index is described.Comment: LaTeX, 19 page
Chromosome mapping: radiation hybrid data and stochastic spin models
This work approaches human chromosome mapping by developing algorithms for
ordering markers associated with radiation hybrid data. Motivated by recent
work of Boehnke et al. [1], we formulate the ordering problem by developing
stochastic spin models to search for minimum-break marker configurations. As a
particular application, the methods developed are applied to 14 human
chromosome-21 markers tested by Cox et al. [2]. The methods generate
configurations consistent with the best found by others. Additionally, we find
that the set of low-lying configurations is described by a Markov-like ordering
probability distribution. The distribution displays cluster correlations
reflecting closely linked loci.Comment: 26 Pages, uuencoded LaTex, Submitted to Phys. Rev. E,
[email protected], [email protected]
Quantum transport and momentum conserving dephasing
We study numerically the influence of momentum-conserving dephasing on the
transport in a disordered chain of scatterers. Loss of phase memory is caused
by coupling the transport channels to dephasing reservoirs. In contrast to
previously used models, the dephasing reservoirs are linked to the transport
channels between the scatterers, and momentum conserving dephasing can be
investigated. Our setup provides a model for nanosystems exhibiting conductance
quantization at higher temperatures in spite of the presence of phononic
interaction. We are able to confirm numerically some theoretical predictions.Comment: 7 pages, 4 figure
Charge pumping in a quantum wire driven by a series of local time-periodic potentials
We develop a method to calculate electronic transport properties through a
mesoscopic scattering region in the presence of a series of time-periodic
potentials. Using the method, the quantum charge pumping driven by
time-periodic potentials is studied. Jumps in the pumped current are observed
at the peak positions of the Wigner delay time. Our main results in both the
weak pumping and strong pumping regimes are consistent with experimental
results. More interestingly, we also observed the nonzero pumping at the phase
difference phi=0 and addressed its relevance to the experimental result.Comment: 5 page
Ultrasound-evoked immediate early gene expression in the brainstem of the Chinese torrent frog, Odorrana tormota
The concave-eared torrent frog, Odorrana tormota, has evolved the extraordinary ability to communicate ultrasonically (i.e., using frequencies > 20 kHz), and electrophysiological experiments have demonstrated that neurons in the frog’s midbrain (torus semicircularis) respond to frequencies up to 34 kHz. However, at this time, it is unclear which region(s) of the torus and what other brainstem nuclei are involved in the detection of ultrasound. To gain insight into the anatomical substrate of ultrasound detection, we mapped expression of the activity-dependent gene, egr-1, in the brain in response to a full-spectrum mating call, a filtered, ultrasound-only call, and no sound. We found that the ultrasound-only call elicited egr-1 expression in the superior olivary and principal nucleus of the torus semicircularis. In sampled areas of the principal nucleus, the ultrasound-only call tended to evoke higher egr-1 expression than the full-spectrum call and, in the center of the nucleus, induced significantly higher egr-1 levels than the no-sound control. In the superior olivary nucleus, the full-spectrum and ultrasound-only calls evoked similar levels of expression that were significantly greater than the control, and egr-1 induction in the laminar nucleus showed no evidence of acoustic modulation. These data suggest that the sampled areas of the principal nucleus are among the regions sensitive to ultrasound in this species
The Chicken Yolk Sac IgY Receptor, a Mammalian Mannose Receptor Family Member, Transcytoses IgY across Polarized Epithelial Cells
In mammals the transfer of passive immunity from mother to young is mediated by the MHC-related receptor FcRn, which transports maternal IgG across epithelial cell barriers. In birds, maternal IgY in egg yolk is transferred across the yolk sac to passively immunize chicks during gestation and early independent life. The chicken yolk sac IgY receptor (FcRY) is the ortholog of the mammalian phospholipase A2 receptor, a mannose receptor family member, rather than an FcRn or MHC homolog. FcRn and FcRY both exhibit ligand binding at the acidic pH of endosomes and ligand release at the slightly basic pH of blood. Here we show that FcRY expressed in polarized mammalian epithelial cells functioned in endocytosis, bidirectional transcytosis, and recycling of chicken FcY/IgY. Confocal immunofluorescence studies demonstrated that IgY binding and endocytosis occurred at acidic but not basic pH, mimicking pH-dependent uptake of IgG by FcRn. Colocalization studies showed FcRY-mediated internalization via clathrin-coated pits and transport involving early and recycling endosomes. Disruption of microtubules partially inhibited apical-to-basolateral and basolateral-to-apical transcytosis, but not recycling, suggesting the use of different trafficking machinery. Our results represent the first cell biological evidence of functional equivalence between FcRY and FcRn and provide an intriguing example of how evolution can give rise to systems in which similar biological requirements in different species are satisfied utilizing distinct protein folds
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Remedial action planning for Trench 1
The accelerated action to remove the depleted uranium chips and associated soils and wastes from Trench 1 at the Rocky Flats Environmental Technology Site (RFETS) will begin in June 1998. To ensure that the remedial action is conducted safely, a rigorous and disciplined planning process was followed that incorporates the principles of Integrated Safety Management and Enhanced Work Planning. Critical to the success of the planning was early involvement of project staff (salaried and hourly) and associated technical support groups and disciplines. Feedback was and will continue to be solicited, and lessons learned incorporated to ensure the safe remediation of this site
Correlation functions near Modulated and Rough Surfaces
In a system with long-ranged correlations, the behavior of correlation
functions is sensitive to the presence of a boundary. We show that surface
deformations strongly modify this behavior as compared to a flat surface. The
modified near surface correlations can be measured by scattering probes. To
determine these correlations, we develop a perturbative calculation in the
deformations in height from a flat surface. Detailed results are given for a
regularly patterned surface, as well as for a self-affinely rough surface with
roughness exponent . By combining this perturbative calculation in
height deformations with the field-theoretic renormalization group approach, we
also estimate the values of critical exponents governing the behavior of the
decay of correlation functions near a self-affinely rough surface. We find that
for the interacting theory, a large enough can lead to novel surface
critical behavior. We also provide scaling relations between roughness induced
critical exponents for thermodynamic surface quantities.Comment: 31 pages, 2 figure
Testing QCD with Hypothetical Tau Leptons
We construct new tests of perturbative QCD by considering a hypothetical tau
lepton of arbitrary mass, which decays hadronically through the electromagnetic
current. We can explicitly compute its hadronic width ratio directly as an
integral over the e^+ e^- annihilation cross section ratio, R_{e^+e^-}.
Furthermore, we can design a set of commensurate scale relations and
perturbative QCD tests by varying the weight function away from the form
associated with the V-A decay of the physical tau. This method allows the wide
range of the R_{e^+e^-} data to be used as a probe of perturbative QCD.Comment: 4 pages, 4 figure
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