27 research outputs found

    Cloud Computing Data Security: A Review

    Get PDF
    Cloud computing has great potential of providing robust computational power to the society at reduced cost. With the advent of the World Wide Web and the emergence of e-commerce applications and social networks, organizations across the world generate a large amount of data daily. This data would be more useful to cooperating organizations if they were able to share their data. Two major obstacles to this process of data sharing are providing a common storage space and secure access to the shared data. All types of users who require the secure transmission or storage of data in any kind of media or network. We are in great need of encrypting the data. A method to build a trusted computing environment for Cloud Computing system by providing Secure cross platform in to Cloud Computing system. In this method some important security services including authentication, encryption and decryption are provided in Cloud Computing system. In this paper, we propose Data Storage Security by using Trusted Platform Module to achieve storage correctness incorporating Cloud’s dynamic nature while maintaining low computation and communication cost and ensures the security of static data

    Monoamine oxidase-dependent endoplasmic reticulum-mitochondria dysfunction and mast cell degranulation lead to adverse cardiac remodeling in diabetes.

    Get PDF
    Monoamine oxidase (MAO) inhibitors ameliorate contractile function in diabetic animals, but the mechanisms remain unknown. Equally elusive is the interplay between the cardiomyocyte alterations induced by hyperglycemia and the accompanying inflammation. Here we show that exposure of primary cardiomyocytes to high glucose and pro-inflammatory stimuli leads to MAO-dependent increase in reactive oxygen species that causes permeability transition pore opening and mitochondrial dysfunction. These events occur upstream of endoplasmic reticulum (ER) stress and are abolished by the MAO inhibitor pargyline, highlighting the role of these flavoenzymes in the ER/mitochondria cross-talk. In vivo, streptozotocin administration to mice induced oxidative changes and ER stress in the heart, events that were abolished by pargyline. Moreover, MAO inhibition prevented both mast cell degranulation and altered collagen deposition, thereby normalizing diastolic function. Taken together, these results elucidate the mechanisms underlying MAO-induced damage in diabetic cardiomyopathy and provide novel evidence for the role of MAOs in inflammation and inter-organelle communication. MAO inhibitors may be considered as a therapeutic option for diabetic complications as well as for other disorders in which mast cell degranulation is a dominant phenomenon

    Solving 0/1 Knapsack Problem Using Hybrid TLBO-GA Algorithm

    No full text

    COMPARATIVE STUDY OF EDGE BASED LSB MATCHING STEGANOGRAPHY FOR COLOR IMAGES

    No full text
    Steganography is a very pivotal technique mainly used for covert transfer of information over a covert communication channel. This paper proposes a significant comparative study of the spatial LSB domain technique that focuses on sharper edges of the color as well as gray scale images for the purpose of data hiding and hides secret message first in sharper edge regions and then in smooth regions of the image. Message embedding depends on content of the image and message size. The experimental results illustrate that, for low embedding rate the method hides the message in sharp edges of cover image to get better stego image visualization quality. For high embedding rate, smooth regions and edges of the cover image are used for the purpose of data hiding. In this steganography method, color image and textured kind of image preserves better visual quality of stego image. The novelty of the comparative study is that, it helps to analyze the efficiency and performance of the method as it gives better results because it directly works on color images instead of converting to gray scale image

    Conscious sedation using dexmedetomidine for percutaneous transcatheter closure of atrial septal defects: A single center experience

    No full text
    Objective: The aim of this study is to determine safety and feasibility of conscious sedation using dexmedetomidine for transcatheter atrial septal defect (ASD) device closure. Material and Methods: A retrospective institutional review of transcatheter ASD device closure without endotracheal intubation over 18 months. The protocol included topical oropharyngeal anesthesia using lignocaine followed by dexmedetomidine bolus 1 μg/kg intravenously over 10 min and maintenance dose 0.2-0.7 μg/kg/h. Ramsay sedation score 2-3 was maintained. Patients were analyzed regarding demographic profile, device size, procedure time, anesthesia time, recovery time, hospital stay, and any hemodynamic or procedural complications. Results: A total of 43 patients with mean age 31.56 ± 13.74 years (range: 12-56 years) were analyzed. Mean anesthesia duration was 71.75 + 21.08 min. Mean recovery time was 7.6 ± 3.01 min. 16 females and one male patient required additional propofol with a mean dose of 30.8 ± 10.49 mg. No hemodynamic instability was noted. No patient required general anesthesia with endotracheal intubation. The procedure was successful in 93.02% of patients. Four patients developed atrial fibrillation. All patients were satisfied. Conclusion: Conscious sedation using dexmedetomidine is a safe and effective anesthetic technique for percutaneous ASD closure
    corecore