5-(4-Chloro­phen­yl)-1-methyl-3-oxocyclo­hexa­necarbonitrile

In the title mol­ecule, C14H14ClNO, the cyclo­hexane ring adopts a chair conformation. The cyano group and the methyl group have axial and equatorial orientations, respectively. The benzene ring has an equatorial orientation. A C—H⋯π inter­action involving the benzene ring is found in the crystal structure

Clinical profile of patients with cardiac syndrome X in a tertiary care hospital

Background: Abnormalities in coronary microcirculation may lead to symptoms of chest pain which mimics angina. Symptoms of chest pain along with evidence of ischemia on non-invasive tests like electrocardiography (ECG), echocardiography or treadmill test (TMT) but with normal coronary angiogram (CAG) is referred to as cardiac syndrome X (CSX). Previous studies have shown favourable prognosis in such patients. However recent studies have not shown good prognosis. We intend to understand whether such adverse cardiovascular outcomes could be secondary to any change in the clinical characteristics of patients with CSX in the current era.Methods: This is a retrospective study which was conducted at a tertiary care hospital. CAG of patients who underwent coronary angiography between November 2013 and October 2016, for suspected ischemic heart disease was reviewed. Clinical characteristics of patients with normal or non-obstructive coronaries (less than 50% stenosis) in angiography with chest pain were analyzed. Further clinical characteristics, ECG, echocardiography, treadmill test and CAG findings were compared among males and females.Results: 410 patients were included in the study. 212 were females and 198 were males. Mean age of presentation was 53.46±10.5 years for males and 55.04±9.3 years for females. Patients presenting with atypical chest pain were higher (70.7%). There were 195 subjects with systemic hypertension, 103 with diabetes mellitus and 57 had dyslipidemia. In the study, most 260 subjects had ST-T changes on ECG. Abnormal echocardiography was seen in only 35 patients. 30.5% patients showed positive stress test for inducible ischemia.Conclusions: CSX is prevalent in significant number of patients who present with symptoms of chest pain. Unlike previous studies, there is no significant difference among males and females, in prevalence and risk factors for this syndrome. Further non-obstructive lesions were found to be higher in females

Structural heat treatments against Tribolium castaneum (Herbst) (Coleoptera: Tenebrionidae): effect of flour depth, life stage and floor.

The effect of high temperatures (50-60°C) and two levels of sanitation (~0.5 and 43 g of flour), on mortality of eggs, young larvae, old larvae, pupae, and adults of the red flour beetle, Tribolium castaneum, were evaluated during heat treatment of a pilot flour mill at Kansas State University. The mill was heated once during 13-14 May 2009 and once during 25-26 August 2009. Each of the heat treatments lasted 24 h. Bioassay boxes, with life stages of T. castaneum and temperature sensors confined in small compartments, were placed in 25 locations across all five mill floors. Temperature data showed that the mean time to 50°C based on the two treatments ranged from 10.39 to 17.18 h, and the mean time above 50°C ranged from 6.01 to 13.63 h. The mean maximum temperatures attained ranged from 50.7 to 61.4°C. In general, temperatures were lower in compartments with 43 g of flour when compared with compartments with 0.5 g of flour. Temperatures were also lower on the first floor than on the remaining floors. In box bioassays, essentially none of the life stages survived the 24 h heat treatment (99-100% mortality), except on the first floor. The survival of insects, especially on the first floor, is related to how quickly temperatures reached 50°C and how long temperatures were held between 50 and 60°C, and the maximum temperatures attained at a given location. There were only small differences in mortality between the two levels of sanitation. These results show that heat treatment of flour mills can control all life stages of T. castaneum in 24 h. Keywords: Tribolium castaneum, Heat treatment, Sanitation, Life stages, Methyl bromide alternative

Heat treatment: A viable methyl bromide alternative for managing stored-product insects in food-processing facilities

Heat treatment involves raising and maintaining temperatures of grain storage structures, warehouses, and food-processing facilities between 50 to 60°C to manage stored-product insect species. The duration of heat treatment is application-specific and may vary from 6 h for an empty storage facility to 24 h for an entire food-processing facility. Laboratory and commercial trials with high temperatures during the last decade, especially with forced air gas heaters, have resulted in a wealth of information on (1) understanding responses of insect species and life stages to heat, (2) heat distribution within a treated area, and (3) techniques necessary for gauging effectiveness of commercial heat treatments. Insect responses vary with the temperature, among species, and within a species among life stages. Air movement and strategic placement of fans are important for eliminating cool spots.Keywords: Heat, Forced air, Flour mills, Methyl bromide alternativ

Equilibrium Moisture Content of Kabuli, Chickpea, Black Sesame, and White Sesame Seeds

Sesame and chickpea are important crops in Ethiopia because both are major export crops that generate much revenue for both small farmers and the country as a whole. However, there is a lack of information about the fundamental equilibrium moisture content (EMC) relationships among these crops, which would help facilitate better monitoring and storage. Therefore, EMC adsorption and desorption prediction models based on temperature (T) and relative humidity (RH) were developed for the modified Chung-Pfost and modified Henderson models for Kabuli chickpea (KC), black sesame (BS), and white sesame (WS) seeds. The samples for conducting the adsorption and desorption tests were conditioned to various moisture content (MC) levels for the EMC test models. The samples (~500 g) were placed in multiple sealed enclosures equipped with T and RH sensors, which were placed in an environmental chamber where they were exposed to three temperatures (15°C, 25°C, and 35°C). The MCdb ranges used for model development for adsorption and desorption were, respectively, 11.6% to 19.5% and 8.9% to 16.9% for KC samples, 5.0% to 8.7% and 4.3% to 6.9% for BS, and 4.2% to 8.7% and 3.5% to 7.6% for WS. Nonlinear regression was used to determine the model coefficients for the modified Henderson and modified Chung-Pfost equations. The prediction statistics for the adsorption and desorption models yielded an SEE of, respectively, 0.53% and 0.68% MCdb for KC, 0.23% and 0.13% for BS, and 0.28% and 0.25% for WS. The model coefficients obtained in this study will be used in a moisture meter based on EMC measurement, which is currently being used as part of a USAID postharvest project in various African and Asian countries. These EMC models may also be important for other grain operations, which include harvesting, drying, storage, conditioning, and processing

Stenosis in single coronary artery originating from right sinus of valsalva: asymptomatic upto sixth decade of life

Among all coronary anomalies, the prevalence of single coronary artery (SCA) originating from right sinus of Valsalva is 1.3%. Here, we report a rare case of a 60-years-old male serendipitously diagnosed with SCA originating from right aortic sinus with pre-pulmonic course of anomalous left coronary artery (LCA). His angiogram revealed 90% stenosis in distal right coronary artery with normal anomalous LCA. Thus, the patient was treated with percutaneous coronary intervention using a stent and was found stable post-procedure