247 research outputs found
Dumping and Double Crossing: The (In)Effectiveness of Cost-Based Trade Policy Under Incomplete Information
We argue that the rise of antidumping protection and the proliferation of voluntary export restraints are fundamentally inter-related. We show that both can be explained by a cost-based definition of dumping when the domestic government has incomplete information about the foreign firm's costs. Given that its costs are only imperfectly observed and knowing the government's desire to offer greater protection against competitively priced imports, efficient foreign firms will voluntarily restrain their exports prior to the antidumping investigation. In turn, the VER distorts the government's perception of the foreign firm's efficiency and often leads to undesirably high duties regardless of the foreign firm's efficiency. The clumsy way that duties are levied benefits domestic firms, which explains the popularity of cost-based complaints.
Tariff Policy for a Monopolist Under Incomplete Information
We examine the incentives for a government to levy an optimal tariff on a foreign monopolist. With complete information, the home government uses tariffs to extract rents and therefore implements a policy of discriminatory tariffs entailing higher tariffs on more efficient firms. By contrast if the government is incompletely informed about costs, we show that under reasonable conditions the unique self-enforcing outcome involves pooling where firms export the same quantity regardless of efficiency. Due to the distortions created by incomplete information we find that in general, home country welfare is higher under a policy of uniform tariffs than under one of discriminatory tariffs. Our results suggest that trade policies that are motivated by rent extraction are unlikely to be robust to the introduction of incomplete information.
Ecological comparison of the risks of mother-to-child transmission and clinical manifestations of congenital toxoplasmosis according to prenatal treatment protocol
We compared the relative risks of mother-to-child transmission of Toxoplasma gondii and clinical manifestations due to congenital toxoplasmosis associated with intensive prenatal treatment in Lyon and Austria, short term treatment in 51% of Dutch women, and no treatment in Danish women. For each cohort, relative risks were standardized for gestation at seroconversion. In total, 856 mother–child pairs were studied: 549 in Lyon, 133 in Austria, 123 in Denmark and 51 in The Netherlands. The relative risk for mother-to-child transmission compared to Lyon was 1·24 (95% CI: 0·88, 1·59) in Austria; 0·59 (0·41, 0·81) in Denmark; and 0·65 (0·37, 1·01) in The Netherlands. Relative risks for clinical manifestations compared with Lyon (adjusted for follow-up to age 3 years) were: Austria 0·19 (0·04, 0·51); Denmark 0·60 (0·13, 1·08); and The Netherlands 1·46 (0·51, 2·72). There was no clear evidence that the risk of transmission or of clinical manifestations was lowest in centres with the most intensive prenatal treatment
Effects of Triticale-Based Diets on Finishing Pig Performance and Pork Quality in Deep-Bedded Hoop Barns
Effects of triticale-based diets on finishing pig performance and pork quality in deep-bedded hoop barns were evaluated. Triticale is a synthetic small grain resulting from a cross between durum wheat and rye. The study consisted of four trials: two in winter (November 2003 through March 2004) and two in summer (May 2004 through September 2004) at the ISU Western Research and Demonstration Farm, Castana, IA. Each trial consisted of six pens of ten pigs (five barrows, five gilts) in three smallscale hoop barns (6.0 × 10.8 m). Pens were randomly assigned one dietary treatment: 1) corn-soybean meal control, 2) 40% Trical 815 triticale diet (by weight) or 3) 80% Trical 815 triticale diet (by weight). The 40 and 80% triticale diets had corn and soybean meal added. Animals had ad libitum access to feed and water during the study. Pigs were started on experiment at approximately 72 kg and fed for 49 d. At the end of each trial all pigs were scanned for backfat thickness and loin muscle area. Barrows from one winter and one summer trial were evaluated for meat and fat quality and sensory evaluation of pork. End weights and ADG were greater during the winter than summer (treatment × season interaction P \u3c 0.01) and decreased as triticale inclusion increased (P \u3c 0.001). Feed intake was similar. Pigs fed the control diet had the greatest G:F, those fed the 80% triticale diet had the least, with pigs fed the 40% triticale diet having intermediate G:F. During the summer, pigs fed the control diet had more BF (P \u3c 0.05) than those fed the triticale diets. Also during summer, pigs fed the control diet had the largest loin muscle area (LMA) (47.5 ± 1.72 cm2); pigs fed the 40% triticale diet had intermediate LMA (45.5 ± 1.72 cm2) and those fed the 80% triticale diet had the smallest LMA (43.4 ± 1.73 cm2). Dietary treatment had no effect on carcass weight, BF, LMA, percentage lean of barrows or sensory evaluation or fatty acid profile of loin chops. Ultimate pH was higher (P \u3c 0.001), percentage loin purge was less (P \u3c 0.05) and shear force (kg) was less (P \u3c 0.05) during summer than winter. Total monounsaturated fatty acids (MUFA) were greater (P \u3c 0.05) and total PUFA in loins were less (P \u3c 0.01) during the winter than summer. Replacing corn with triticale in finishing pig diets in hoops slightly decreased growth performance, but did not affect pork quality. Increasing the amount of triticale in finishing pig diets decreased dietary soybean meal and dicalcium phosphate levels. This may reduce dietary costs. However, pigs fed triticale had 10% less average daily gain and 13% poorer feed conversion at the greater inclusion rate (80% of the diet). This may offset the potentially lower dietary costs. Triticale can be fed to pigs without compromising pork or fat quality. There was no difference in pork eating quality from pigs fed corn-based or triticale-based diets, according to a trained sensory evaluation panel. Further research on triticale-based swine diets is warranted. Triticale-based diets in deep-bedded hoop barns should be evaluated when dietary fat is added, as finishing pig performance may be enhanced. An economic analysis should be conducted on utilization of triticale as a feedstuff in swine diets fed to finishing pigs in deep-bedded hoop barns. From the results of this study, triticale has potential as a feed grain crop in integrated crop and livestock enterprises in the Midwest U. S
Effects of Triticale-Based Diets fed in Deep-Bedded Hoop Barns on Finishing Pig Performance and Pork Quality
Triticale is a synthetic small grain that results from an intergeneric cross between durum wheat and rye. Triticale has shown potential as a feedstuff in swine diets. Producers who may find this to be an attractive crop may also raise swine in an alternative swine production system. The objective of the present study was to evaluate the effects of triticale-based diets on pork quality and finishing pig performance of pigs reared in deep-bedded hoop barns
Multi-scale waves in sound-proof global simulations with EULAG
EULAG is a computational model for simulating flows across a wide range of scales and physical scenarios. A standard option employs an anelastic approximation to capture nonhydrostatic effects and simultaneously filter sound waves from the solution. In this study, we examine a localized gravity wave packet generated by instabilities in Held-Suarez climates. Although still simplified versus the Earth’s atmosphere, a rich set of planetary wave instabilities and ensuing radiated gravity waves can arise. Wave packets are observed that have lifetimes ≤ 2 days, are negligibly impacted by Coriolis force, and do not show the rotational effects of differential jet advection typical of inertia-gravity waves. Linear modal analysis shows that wavelength, period, and phase speed fit the dispersion equation to within a mean difference of ∼ 4%, suggesting an excellent fit. However, the group velocities match poorly even though a propagation of uncertainty analysis indicates that they should be predicted as well as the phase velocities. Theoretical arguments suggest the discrepancy is due to nonlinearity — a strong southerly flow leads to a critical surface forming to the southwest of the wave packet that prevents the expected propagation
Determinants of response to a parent questionnaire about development and behaviour in 3 year olds: European multicentre study of congenital toxoplasmosis.
Background:
We aimed to determine how response to a parent-completed postal questionnaire measuring development, behaviour, impairment, and parental concerns and anxiety, varies in different European centres.
Methods:
Prospective cohort study of 3 year old children, with and without congenital toxoplasmosis, who were identified by prenatal or neonatal screening for toxoplasmosis in 11 centres in 7 countries. Parents were mailed a questionnaire that comprised all or part of existing validated tools. We determined the effect of characteristics of the centre and child on response, age at questionnaire completion, and response to child drawing tasks.
Results:
The questionnaire took 21 minutes to complete on average. 67% (714/1058) of parents responded. Few parents (60/1058) refused to participate. The strongest determinants of response were the score for organisational attributes of the study centre (such as direct involvement in follow up and access to an address register), and infection with congenital toxoplasmosis. Age at completion was associated with study centre, presence of neurological abnormalities in early infancy, and duration of prenatal treatment. Completion rates for individual questions exceeded 92% except for child completed drawings of a man (70%), which were completed more by girls, older children, and in certain centres.
Conclusion:
Differences in response across European centres were predominantly related to the organisation of follow up and access to correct addresses. The questionnaire was acceptable in all six countries and offers a low cost tool for assessing development, behaviour, and parental concerns and anxiety, in multinational studies
Association between congenital toxoplasmosis and parent-reported developmental outcomes, concerns, and impairments in 3 year old children
Background: Information is lacking on the effects of congenital toxoplasmosis on development, behavior, and impairment in later childhood, as well as on parental concerns and anxiety. This information is important for counselling parents about the prognosis for an infected child and for policy decisions on screening. Methods: We prospectively studied a cohort of children identified by screening for toxoplasmosis in pregnant women or neonates between 1996 and 2000 in ten European centers. At 3 years of age, parents of children with and without congenital toxoplasmosis were surveyed about their child's development, behavior, and impairment, and about parental concerns and anxiety, using a postal questionnaire. Results: Parents of 178/223 (80%) infected, and 527/821 (64%) uninfected children responded. We found no evidence that impaired development or behavior were more common in infected children, or that any potential effect of congenital toxoplasmosis was masked by prenatal treatment. Parents of infected children were significantly more anxious and reported more visual problems in their children. Conclusion: On average, children aged three to four years with congenital toxoplasmosis identified by screening and treated during infancy in this European setting had risks of abnormal development and behavior similar to uninfected children. Parental anxiety about infected children needs to be addressed by clinicians. Future studies with longer follow up and clinician-administered assessments may be better able to detect any subtle differences in child outcomes
Starvation sensing by mycobacterial RelA/SpoT homologue through constitutive surveillance of translation
The stringent response, which leads to persistence of nutrient-starved mycobacteria, is induced by activation of the RelA/SpoT homolog (Rsh) upon entry of a deacylated-tRNA in a translating ribosome. However, the mechanism by which Rsh identifies such ribosomes in vivo remains unclear. Here, we show that conditions inducing ribosome hibernation result in loss of intracellular Rsh in a Clp protease-dependent manner. This loss is also observed in nonstarved cells using mutations in Rsh that block its interaction with the ribosome, indicating that Rsh association with the ribosome is important for Rsh stability. The cryo-EM structure of the Rsh-bound 70S ribosome in a translation initiation complex reveals unknown interactions between the ACT domain of Rsh and components of the ribosomal L7/L12 stalk base, suggesting that the aminoacylation status of A-site tRNA is surveilled during the first cycle of elongation. Altogether, we propose a surveillance model of Rsh activation that originates from its constitutive interaction with the ribosomes entering the translation cycle
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