AC Hopping Magnetotransport Across the Spin Flop Transition in Lightly Doped La_2CuO_4

The weak ferromagnetism present in insulating La_{2}CuO_4 at low doping leads to a spin flop transition, and to transverse (interplane) hopping of holes in a strong external magnetic field. This results in a dimensional crossover 2D $\to$ 3D for the in-plane transport, which in turn leads to an increase of the hole's localization length and increased conduction. We demonstrate theoretically that as a consequence of this mechanism, a frequency-dependent jump of the in-plane ac hopping conductivity occurs at the spin flop transition. We predict the value and the frequency dependence of the jump. Experimental studies of this effect would provide important confirmation of the emerging understanding of lightly doped insulating La_{2-x}Sr_xCuO_4.Comment: 4 pages, 1 figur

Single hole dynamics in dimerized spin liquids

The dynamics of a single hole in quantum antiferromagnets is influenced by magnetic fluctuations. In the present work we consider two situations. The first one corresponds to a single hole in the two leg t-J spin ladder. In this case the wave function renormalization is relatively small and the quasiparticle residue of the S=1/2 state remains close to unity. However at large t/J there are higher spin (S=3/2,5/2,..) bound states of the hole with the magnetic excitations, and therefore there is a crossover from quasiparticles with S=1/2 to quasiparticles with higher spin. The second situation corresponds to a single hole in two coupled antiferromagnetic planes very close to the point of antiferromagnetic instability. In this case the hole wave function renormalization is very strong and the quasiparticle residue vanishes at the point of instability.Comment: 12 pages, 3 figure

Bound states of magnons in the S=1/2 quantum spin ladder

We study the excitation spectrum of the two-leg antiferromagnetic S=1/2 Heisenberg ladder. Our approach is based on the description of the excitations as triplets above a strong-coupling singlet ground state. The quasiparticle spectrum is calculated by treating the excitations as a dilute Bose gas with infinite on-site repulsion. We find singlet (S=0) and triplet (S=1) two-particle bound states of the elementary triplets. We argue that bound states generally exist in any dimerized quantum spin model.Comment: 4 REVTeX pages, 4 Postscript figure

A study of the temperature dependence of bienzyme systems and enzymatic chains

It is known that most enzyme-facilitated reactions are highly temperature dependent processes. In general, the temperature coefficient, Q10, of a simple reaction reaches 2.0-3.0. Nevertheless, some enzyme-controlled processes have much lower Q10 (about 1.0), which implies that the process is almost temperature independent, even if individual reactions involved in the process are themselves highly temperature dependent. In this work, we investigate a possible mechanism for this apparent temperature compensation: simple mathematical models are used to study how varying types of enzyme reactions are affected by temperature. We show that some bienzyme-controlled processes may be almost temperature independent if the modules involved in the reaction have similar temperature dependencies, even if individually, these modules are strongly temperature dependent. Further, we show that in non-reversible enzyme chains the stationary concentrations of metabolites are dependent only on the relationship between the temperature dependencies of the first and last modules, whilst in reversible reactions, there is a dependence on every module. Our findings suggest a mechanism by which the metabolic processes taking place within living organisms may be regulated, despite strong variation in temperature

New quantum phase transitions in the two-dimensional J1-J2 model

We analyze the phase diagram of the frustrated Heisenberg antiferromagnet, the J1-J2 model, in two dimensions. Two quantum phase transitions in the model are already known: the second order transition from the Neel state to the spin liquid state at (J_2/J_1)_{c2}=0.38, and the first order transition from the spin liquid state to the collinear state at (J_2/J_1)_{c4}=0.60. We have found evidence for two new second order phase transitions: the transition from the spin columnar dimerized state to the state with plaquette type modulation at (J_2/J_1)_{c3}=0.50(2), and the transition from the simple Neel state to the Neel state with spin columnar dimerization at (J_2/J_1)_{c1}=0.34(4). We also present an independent calculation of (J_2/J_1)_{c2}=0.38 using a new approach.Comment: 3 pages, 5 figures; added referenc

On the nature of the transition from the spontaneously dimerized to the Neel phase in the two-dimensional J1-J2 model

We analyze the spectrum of the 2D S=1/2 frustrated Heisenberg model near the transition from the spontaneously dimerized spin-liquid phase into the Neel ordered phase. Two excitation branches: the triplet magnon, and the collective singlet mode, both become gapless at the transition point. However we find that the length scales associated with these modes are well separated at the quantum transition. While in the quantum disordered phase the singlet excitation has finite spectral weight and reflects the existence of spontaneous dimer order, near the transition point the size of the singlet bound state grows exponentially with the correlation length, and hence the quasiparticle residue is exponentially small. Therefore the critical dynamics remains in the O(3) universality class in spite of the four gapless modes.Comment: 5 pages, 3 figure

Soliton binding and low-lying singlets in frustrated odd-legged S=1/2 spin tubes

Motivated by the intriguing properties of the vanadium spin tube Na2V3O7, we show that an effective spin-chirality model similar to that of standard Heisenberg odd-legged S=1/2 spin tubes can be derived for frustrated inter-ring couplings, but with a spin-chirality coupling constant alpha that can be arbitrarily small. Using density matrix renormalization group and analytical arguments, we show that, while spontaneous dimerization is always present, solitons become bound into low-lying singlets as alpha is reduced. Experimental implications for strongly frustrated tubes are discussed.Comment: 4 pages, 4 figure

An antibody raised against a pathogenic serpin variant induces mutant-like behaviour in the wild-type protein

A monoclonal antibody (mAb) that binds to a transient intermediate may act as a catalyst for the corresponding reaction; here we show this principle can extend on a macro molecular scale to the induction of mutant-like oligomerization in a wild-type protein. Using the common pathogenic E342K (Z) variant of α1-antitrypsin as antigen-whose native state is susceptible to the formation of a proto-oligomeric intermediate-we have produced a mAb (5E3) that increases the rate of oligomerization of the wild-type (M) variant. Employing ELISA, gel shift, thermal stability and FRET time-course experiments, we show that mAb5E3 does not bind to the native state of α1-antitrypsin, but recognizes a cryptic epitope in the vicinity of the post-helix A loop and strand 4C that is revealed upon transition to the polymerization intermediate, and which persists in the ensuing oligomer. This epitope is not shared by loop-inserted monomeric conformations. We show the increased amenity to polymerization by either the pathogenic E342K mutation or the binding of mAb5E3 occurs without affecting the energetic barrier to polymerization. As mAb5E3 also does not alter the relative stability of the monomer to intermediate, it acts in a manner similar to the E342K mutant, by facilitating the conformational interchange between these two states

Critical Dynamics of Singlet Excitations in a Frustrated Spin System

We construct and analyze a two-dimensional frustrated quantum spin model with plaquette order, in which the low-energy dynamics is controlled by spin singlets. At a critical value of frustration the singlet spectrum becomes gapless, indicating a quantum transition to a phase with dimer order. This T=0 transition belongs to the 3D Ising universality class, while at finite temperature a 2D Ising critical line separates the plaquette and dimerized phases. The magnetic susceptibility has an activated form throughout the phase diagram, whereas the specific heat exhibits a rich structure and a power law dependence on temperature at the quantum critical point. We argue that the novel quantum critical behavior associated with singlet criticality discussed in this work can be relevant to a wide class of quantum spin systems, such as antiferromagnets on Kagome and pyrochlore lattices, where the low-energy excitations are known to be spin singlets, as well as to the CAVO lattice and several recently discovered strongly frustrated square-lattice antiferromagnets.Comment: 5 pages, 5 figures, additional discussion and figure added, to appear in Phys. Rev.