EXPERIENCE OF LAPAROSCOPIC REHABILITATION AFTER OPERATIONS ON LOCAL PERITONITIS

Evaluated the results of examination and treatment of 37 patients who were hospitalized for  surgical  in Belarus for  the  period  2000  to 2010. The experience of  dynamic  remedial laparoscopy under  local postoperative peritonitis with the use of lysozyme and polyvalent piobakteriofaga shows  the  effectiveness of this method can reduce  mortality  and  reduce treatment time by an average of 3 ± 1,3 day in chronic inflammatory diseases  caused  by associations of St. Aureus with Pr. vulgaris, Morganella morganii and Enterobacter aggl

Synthesis and Reactivity of Mn–CF3 Complexes

The synthesis, characterization and reactivity of several bi- and tridentate, N-ligated manganese carbonyl trifluoromethyl complexes are presented. These complexes exhibit elongated Mn–CCF3 bonds (versus Mn(CF3)(CO)5), suggesting a lability that could be utilized for the transfer or insertion of the CF3 functional group into organic substrates. Unlike their Mn–X congeners (X = Cl, Br), these Mn–CF3 complexes exhibit a preference for hard donor ancillary ligands, thus enabling the synthesis of 4 N-ligated Mn–CF3 complexes including a mixed-donor tridentate complex using an NNS Schiff base ([2-(methylthio)-N-(1-(pyridin-2-yl)ethylidene)aniline]). Although we have not yet identified efficient CF3 transfer reactions, fluoride abstraction from the Mn–CF3 complexes using trimethylsilyl triflate affords the first stable Mn fluorocarbenes as evidenced by 19F NMR spectroscopy

Selective Copper Complex-Catalyzed Hydrodefluorination of Fluoroalkenes and Allyl Fluorides: A Tale of Two Mechanisms

The transition to more economically friendly small-chain fluorinated groups is leading to a resurgence in the synthesis and reactivity of fluoroalkenes. One versatile method to obtain a variety of commercially relevant hydrofluoroalkenes involves the catalytic hydrodefluorination (HDF) of fluoroalkenes using silanes. In this work it is shown that copper hydride complexes of tertiary phosphorus ligands (L) can be tuned to achieve selective multiple HDF of fluoroalkenes. In one example, HDF of the hexafluoropropene dimer affords a single isomer of heptafluoro-2-methylpentene in which five fluorines have been selectively replaced with hydrogens. DFT computational studies suggest a distinct HDF mechanisms for L2CuH (bidentate or bulky monodentate phosphines) and L3CuH (small cone angle monodentate phosphines) catalysts, allowing for stereocontrol of the HDF of trifluoroethylene

Single-molecule magnet behaviour in a tetranuclear Dy III complex formed from a novel tetrazine-centered hydrazone Schiff base ligand

International audienc

Nickel-Catalyzed Homologation of Vinylidene Difluoride (CH₂CF₂): Selective β‑F <i>vs</i> β‑H Elimination

Hydrofluoroolefins (HFOs) constitute the newest generation of fluorocarbon refrigerants and foam-blowing agents due to their reduced global warming potential vs their saturated analogues. To identify new synthetic routes to HFOs, we show that reactions of bulky Ni(0) phosphine and −NHC complexes with vinylidene difluoride (VF2) afford μ-fluoro-1,1,3-trifluorobut-3-enyl Ni complexes. Moreover, addition of triisopropylsilane allows for reductive elimination of the reduced product2,4,4-trifluoro-1-butenedemonstrating the Ni-catalyzed hydrodefluorodimerization of VF2. Accompanying DFT calculations identify the T-shaped nickelacyclopentane intermediate that spontaneously undergoes selective intramolecular β-F (vs β-H) elimination

ОПЫТ ЛАПАРОСКОПИЧЕСКИХ САНАЦИЙ ПОСЛЕ ОПЕРАЦИЙ ПО ПОВОДУ МЕСТНОГО ПЕРИТОНИТА

Evaluated the results of examination and treatment of 37 patients who were hospitalized for  surgical  in Belarus for  the  period  2000  to 2010. The experience of  dynamic  remedial laparoscopy under  local postoperative peritonitis with the use of lysozyme and polyvalent piobakteriofaga shows  the  effectiveness of this method can reduce  mortality  and  reduce treatment time by an average of 3 ± 1,3 day in chronic inflammatory diseases  caused  by associations of St. Aureus with Pr. vulgaris, Morganella morganii and Enterobacter aggl.Оценены результаты обследования и лечения 37 больных  хирургического профиля, находившихся на стационарном лечении в РБ за период с 2000  по 2010 гг. Опыт проведения динамической санационной лапароскопии при местном  послеоперационном  перитоните с использованием лизоцима и поливалентного пиобактериофага показывает эффективность данного метода, способствует  снижению  летальности и сокращению сроков  лечения  в среднем на 3±1,3  сутки при  гнойно-воспалительных заболеваниях, вызванных ассоциациями St. Aureus с Pr. vulgaris, Morganellamorganii и Enterobacteraggl