Восстановлены наблюдения на ледниках Актру на Алтае

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SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18–49, 50–69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in surgical patients than the general population. The most favourable NNVs were in patients aged 70 years or more needing cancer surgery (351; best case 196, worst case 816) or non-cancer surgery (733; best case 407, worst case 1664). Both exceeded the NNV in the general population (1840; best case 1196, worst case 3066). NNVs for surgical patients remained favourable at a range of SARS-CoV-2 incidence rates in sensitivity analysis modelling. Globally, prioritizing preoperative vaccination of patients needing elective surgery ahead of the general population could prevent an additional 58 687 (best case 115 007, worst case 20 177) COVID-19-related deaths in 1 year. Conclusion As global roll out of SARS-CoV-2 vaccination proceeds, patients needing elective surgery should be prioritized ahead of the general population

Recent Developments and New Directions in Soft Computing

VIII, 466 p. 181 illus., 35 illus. in color.onlin

Evaluation of surgical treatment of coronary heart disease with a low ejection fraction

The immediate results of the surgical treatment of coronary heart disease (CHD) patients with a low left ventricular ejection fraction and moderate mitral regurgitation (MR) were analyzed. Patients were divided into two groups: in group 1 - 30 patients with coronary artery bypass grafting (CABG) in combination with mitral valve reconstruction; group 2 - 30 patients with isolated CABG. Hospital mortality in group 1 and 2 were 3.3%. Noted that the degree of MR in group 1 were decreased when compared with group 2.Анализируется непосредственные результаты хирургического лечения больных ИБО с низкой фракцией выброса левого желудочка и умеренной митральной недостаточностью (МН). Больные были разделены на две группы: группа 1 – 30 пациент с коронарным шунтированием (КШ) в сочетании с реконструкцией митрального клапана, группа 2-30 пациентов с изолированным КШ. Госпитальная летальность в обеих группах 1 составила 3,3 %. Доказано снижение степени МН у пациентов в группе с КШ в сочетании с реконструкцией митрального клапана при дисфункции левого желудочка