Inhibitory Activity of Extracts of Top Botanical Candidates.

<p>Inhibitory Activity of Extracts of Top Botanical Candidates.</p

HPLC gradient conditions.

<p>HPLC gradient conditions.</p

Cell viability after exposure to top botanical candidates.

<p>MTT assay was utilized to determine % cell viability of Hep G2 cells after 72 hr exposure to increasing doses of the top four botanical extracts (Lot #1). (A) <i>Angelica archangelica</i>, (B) <i>Scutellaria baicalensis</i>, (C) <i>Petroselinum crispum</i>, and (D) <i>Garcinia mangostana</i>.</p

HPLC chromatograms of extracts of top botanical candidates.

<p>(A) <i>Angelica archangelica</i>, (B) <i>Scutellaria baicalensis</i>, (C) <i>Petroselinum crispum</i>, and (D) <i>Garcinia mangostana</i>. The arrows indicate the marker compounds. A1: osthenol, A2: osthole, B1: baicalin, C1: apiin, and D1: α-/γ-mangostin.</p

3-Step recombinant ketohexokinase enzymatic assay.

<p>KHKC Ketohexokinase C isoform. PK pyruvate kinase. LDH lactate dehydrogenase.</p

Inhibitory KHKC Activity of Candidate Botanical Extracts.

<p>Inhibitory KHKC Activity of Candidate Botanical Extracts.</p