1,191 research outputs found
Synchronization of Coupled Chaotic Dynamics on Networks
We review some recent work on the synchronization of coupled dynamical
systems on a variety of networks. When nodes show synchronized behaviour, two
interesting phenomena can be observed. First, there are some nodes of the
floating type that show intermittent behaviour between getting attached to some
clusters and evolving independently. Secondly, two different ways of cluster
formation can be identified, namely self-organized clusters which have mostly
intra-cluster couplings and driven clusters which have mostly inter-cluster
couplings.Comment: 15 pages, 3 figure
What Role Should Acute-on-Chronic Liver Failure Play in Liver Transplant Prioritization? A Survey of US-Based Transplant Providers
Extracorporeal liver support devices in the ICU
Liver failure is common and carries high morbidity and mortality. Liver transplantation (LT) is the only definitive treatment available performed as an emergency in acute liver failure and electively for chronic liver disease. In the last 50 years, a number of extracorporeal liver support devices and modifications have emerged , some of them purely mechanical in nature aimed at detoxification, while others are cell based systems possessing bio-transformational capability. Mechanical devices are mainly based on albumin dialysis, albumin being a key transporter protein that is severely deficient and irreversibly destroyed in liver diseases. Despite a sound scientific rationale and good safety profile, none of the currently available devices have shown enough promise to be incorporated in routine clinical practice, their use being limited to specific clinical situations. This chapter describes currently available devices, their operational characteristics, current evidence of their utility and limitation, and the future developments in the field of extracorporeal liver support
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