2,367 research outputs found

    Cardiovascular collapse caused by carbon dioxide insufflation during one-lung anaesthesia for thoracoscopic dorsal sympathectomy

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    Publisher's copy made available with the permission of the publisherCarbon dioxide insufflation into the pleural space during one-lung anaesthesia for thoracoscopic surgery is used in some centres to improve surgical access, even though this practice has been associated with well-described cardiovascular compromise. The present report is of a 35-year-old woman undergoing thoracoscopic left dorsal sympathectomy for hyperhidrosis. During one-lung anaesthesia the insufflation of carbon dioxide into the non-ventilated hemithorax for approximately 60 seconds, using a pressure-limited gas inflow, was accompanied by profound bradycardia and hypotension that resolved promptly with the release of the gas. Possible mechanisms for the cardiovascular collapse are discussed, and the role of carbon dioxide insufflation as a means of expediting lung collapse for procedures performed using single-lung ventilation is questioned.RJD Harris, G Benveniste, J Pfitznerhttp://www.aaic.net.au/Article.asp?D=200119

    The Value of Liquidity

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/72848/1/1080-8620.00026.pd

    In Vivo 3D Digital Atlas Database of the Adult C57BL/6J Mouse Brain by Magnetic Resonance Microscopy

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    In this study, a 3D digital atlas of the live mouse brain based on magnetic resonance microscopy (MRM) is presented. C57BL/6J adult mouse brains were imaged in vivo on a 9.4 Tesla MR instrument at an isotropic spatial resolution of 100 μm. With sufficient signal-to-noise (SNR) and contrast-to-noise ratio (CNR), 20 brain regions were identified. Several atlases were constructed including 12 individual brain atlases, an average atlas, a probabilistic atlas and average geometrical deformation maps. We also investigated the feasibility of using lower spatial resolution images to improve time efficiency for future morphological phenotyping. All of the new in vivo data were compared to previous published in vitro C57BL/6J mouse brain atlases and the morphological differences were characterized. Our analyses revealed significant volumetric as well as unexpected geometrical differences between the in vivo and in vitro brain groups which in some instances were predictable (e.g. collapsed and smaller ventricles in vitro) but not in other instances. Based on these findings we conclude that although in vitro datasets, compared to in vivo images, offer higher spatial resolutions, superior SNR and CNR, leading to improved image segmentation, in vivo atlases are likely to be an overall better geometric match for in vivo studies, which are necessary for longitudinal examinations of the same animals and for functional brain activation studies. Thus the new in vivo mouse brain atlas dataset presented here is a valuable complement to the current mouse brain atlas collection and will be accessible to the neuroscience community on our public domain mouse brain atlas website

    OBSERVATIONS ON THE RESPONSE OF A LITHIUM-DRIFTED DETECTOR PROTONS

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    The response of a lithium-drifted solid state detector was measured for protons and found to be linear up to the highest energy observed, 13.2 Mev. The resolution observed for these protons is 0.81% with a bias of 500 volts and 0.65% with a bias of 250 volts. (auth

    Tracing international migration in projections of income and inequality across the Shared Socioeconomic Pathways

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    The Shared Socioeconomic Pathways (SSPs) represent five narratives of future development used for climate change research. They include quantified projections of socioeconomic variables such as population, income levels, inequalities, and emissions over the twenty-first century. The SSP’s population projections embody explicit, pathway-specific international migration assumptions, which are only implicit in the projections of other variables. In this contribution, we explicitly quantify the effects of international migration on income levels and income inequality across and within countries by comparing the original SSP projections to scenarios of zero migration. Income projections without migration are obtained by removing two effects of migration on income dynamics: changes in population size and remittances sent to origin countries. We base our remittance estimates on migrant stocks derived from bilateral migration flow estimates obtained from a gravity model. We find that, on average, migration tends to make the world richer in all SSP narratives. The nature of migration and remittance corridors is shaped by the specific scenario of future development considered. Depending on the particular SSP narrative and world region considered, the effects of migration on income can be substantial, ranging from −5 to +21% at the continental level. We show that migration tends to decrease income inequality across countries and within country in most destination countries but does not affect within-country inequality in origin countries. This new set of projections is consistent with the interdisciplinary framework of the SSPs, which makes it particularly useful for assessing global climate and sustainable development policy options
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