78 research outputs found
On Quasiperiodic Morphisms
Weakly and strongly quasiperiodic morphisms are tools introduced to study
quasiperiodic words. Formally they map respectively at least one or any
non-quasiperiodic word to a quasiperiodic word. Considering them both on finite
and infinite words, we get four families of morphisms between which we study
relations. We provide algorithms to decide whether a morphism is strongly
quasiperiodic on finite words or on infinite words.Comment: 12 page
Repetitions in infinite palindrome-rich words
Rich words are characterized by containing the maximum possible number of
distinct palindromes. Several characteristic properties of rich words have been
studied; yet the analysis of repetitions in rich words still involves some
interesting open problems. We address lower bounds on the repetition threshold
of infinite rich words over 2 and 3-letter alphabets, and construct a candidate
infinite rich word over the alphabet with a small critical
exponent of . This represents the first progress on an open
problem of Vesti from 2017.Comment: 12 page
A phase II study of docetaxel in patients with metastatic squamous cell carcinoma of the head and neck
This study was designed to evaluate the activity, safety and tolerance of docetaxel (D) in a selected population with metastatic squamous cell carcinoma of the head and neck (SCCHN). Twenty-four patients with no prior palliative therapy were enrolled and received D 100 mg mâ2 by 1 h of infusion, every 3 weeks. All but two patients had been evaluated for efficacy on lung metastatic sites. No prophylactic administration of anti-emetics or growth factors was given. A pharmacokinetic study was performed in 22 patients. Twenty-one patients were assessable for response and 24 for toxicity. One hundred and four cycles were administered with a median of 4.5 (range 1â9) per patient. The median cumulative dose was 449 mg mâ2. Partial responses were achieved in five patients with a median duration of 18.7 weeks (range 13.1â50.3). The overall response rate was 20.8% with a median duration of 11.0 weeks (range 2.4â52.6). The most frequent side-effect was neutropenia (79.2% grade IV) but with a short duration (median 4 days) and no febrile neutropenia. The incidence of moderate/severe fluid retention was 29.2% with one treatment discontinuation. Other toxicities (all grades) were common (skin 75%, asthenia 50%, infection 29.2%, nausea 16.7%, diarrhoea 12.5%, stomatitis 16.7%, vomiting 8.3% and HSR 8.3%). A mean clearance of 19.6 l hâ1 mâ2 and an area under the curve of 6.00 ÎŒg mlâ1 hâ1 was found in the pharmacokinetic analysis. Docetaxel is active in this selected population with metastatic SCCHN, with a good tolerance. © 1999 Cancer Research Campaig
ABSTRACT
Methods from string and pattern matching have recently been applied to many problems in music retrieval. We consider the so-called lead sheet problem, where the harmony, melody, and, usually, bass line are presented separately. This is a common situation in some forms of popular music but is also significant for âclassical â music in many cases. A number of different but related musical situations are analysed and efficient algorithms are presented for music retrieval in each one. 1
PalladiumâCatalyzed Carboperfluoroalkylation of Alkynes with Fluoroalkyl Iodides and Arylstannanes
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