The automated multi-stage substructuring system for NASTRAN

The substructuring capability developed for eventual installation in Level 16 is now operational in a test version of NASTRAN. Its features are summarized. These include the user-oriented, Case Control type control language, the automated multi-stage matrix processing, the independent direct access data storage facilities, and the static and normal modes solution capabilities. A complete problem analysis sequence is presented with card-by-card description of the user input

Bioengineering Lantibiotics for Therapeutic Success

peer-reviewedSeveral examples of highly modified antimicrobial peptides have been described. While many such peptides are non-ribosomally synthesized, ribosomally synthesized equivalents are being discovered with increased frequency. Of the latter group, the lantibiotics continue to attract most attention. In the present review, we discuss the implementation of in vivo and in vitro engineering systems to alter, and even enhance, the antimicrobial activity, antibacterial spectrum and physico-chemical properties, including heat stability, solubility, diffusion and protease resistance, of these compounds. Additionally, we discuss the potential applications of these lantibiotics for use as therapeutics.DF,CH,PC,RR are supported by the Irish Government under the National Development Plan, through a Science Foundation Ireland (SFI) Technology and Innovation Development Award (TIDA14/TIDA/2286) to DF, a SFI Investigator awards to CH and RR (10/IN.1/B3027),SFI-PIfunding(11/PI/1137) to PDC and the Alimentary Pharmabiotic Centre under Grant Number SFI/12/RC/2273

Production of large transverse momentum dileptons and photons in pppp, dAdA and AAAA collisions by photoproduction processes

The production of large $P_{T}$ dileptons and photons originating from photoproduction processes in $pp$, $dA$ and $AA$ collisions is calculated. We find that the contribution of dileptons and photons produced by photoproduction processes is not prominent at RHIC energies. However, the numerical results indicate that the modification of photoproduction processes becomes evident in the large $P_{T}$ region for $pp$, $dA$ and $AA$ collisions at LHC energies.Comment: 10 figure

Jets associated with Z^0 boson production in heavy-ion collisions at the LHC

The heavy ion program at the LHC will present unprecedented opportunities to probe hot QCD matter, that is, the quark gluon plasma (QGP). Among these exciting new probes are high energy partons associated with the production of a Z^0 boson, or Z^0 tagged jets. Once produced, Z^0 bosons are essentially unaffected by the strongly interacting medium produced in heavy-ion collisions, and therefore provide a powerful signal of the initial partonic energy and subsequent medium induced partonic energy loss. When compared with theory, experimental measurements of Z^0 tagged jets will help quantify the jet quenching properties of the QGP and discriminate between different partonic energy loss formalisms. In what follows, I discuss the advantages of tagged jets over leading particles, and present preliminary results of the production and suppression of Z^0 tagged jets in relativistic heavy-ion collisions at LHC energies using the Guylassy-Levai-Vitev (GLV) partonic energy loss formalism.Comment: To appear in the proceedings of the 2010 Winter Workshop on Nuclear Dynamics, which was held in Ocho Rios, Jamaica, mon

Thermal photon to dilepton ratio in ultra-relativistic heavy ion collisions

The ratio of transverse momentum distribution of thermal photons to dilepton has been evaluated. It is observed that this ratio reaches a plateau beyond a certain value of transverse momentum. We argue that this ratio can be used to estimate the initial temperature of the system by selecting the transverse momentum and invariance mass windows judiciously. It is demonstrated that if the radial flow is large then the plateau disappear and hence a deviation from the plateau can be used as an indicator of large radial flow. The sensitivity of the results on various input parameters has been studied.Comment: 9 pages with 11 eps figure