14,244 research outputs found

    Radiocarbon dates from the Oxford AMS system: archaeometry datelist 35

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    This is the 35th list of AMS radiocarbon determinations measured at the Oxford Radiocarbon Accelerator Unit (ORAU). Amongst some of the sites included here are the latest series of determinations from the key sites of Abydos, El Mirón, Ban Chiang, Grotte de Pigeons (Taforalt), Alepotrypa and Oberkassel, as well as others dating to the Palaeolithic, Mesolithic and later periods. Comments on the significance of the results are provided by the submitters of the material

    Synthesis, Structure and Properties of Tetragonal Sr2M3As2O2 (M3 = Mn3, Mn2Cu and MnZn2) Compounds Containing Alternating CuO2-Type and FeAs-Type Layers

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    Polycrystalline samples of Sr2Mn2CuAs2O2, Sr2Mn3As2O2, and Sr2Zn2MnAs2O2 were synthesized. Their temperature- and applied magnetic field-dependent structural, transport, thermal, and magnetic properties were characterized by means of x-ray and neutron diffraction, electrical resistivity rho, heat capacity, magnetization and magnetic susceptibility measurements. These compounds have a body-centered-tetragonal crystal structure (space group I4/mmm) that consists of MO2 (M = Zn and/or Mn) oxide layers similar to the CuO2 layers in high superconducting transition temperature Tc cuprate superconductors, and intermetallic MAs (M = Cu and/or Mn) layers similar to the FeAs layers in high-Tc pnictides. These two types of layers alternate along the crystallographic c-axis and are separated by Sr atoms. The site occupancies of Mn, Cu and Zn were studied using Rietveld refinements of x-ray and neutron powder diffraction data. The temperature dependences of rho suggest metallic character for Sr2Mn2CuAs2O2 and semiconducting character for Sr2Mn3As2O2 and Sr2Zn2MnAs2O2. Sr2Mn2CuAs2O2 is inferred to be a ferrimagnet with a Curie temperature TC = 95(1) K. Remarkably, we find that the magnetic ground state structure changes from a G-type antiferromagnetic structure in Sr2Mn3As2O2 to an A-type ferrimagnetic structure in Sr2Mn2CuAs2O2 in which the Mn ions in each layer are ferromagnetically aligned, but are antiferromagnetically aligned between layers.Comment: 18 pages, 16 figures, 6 tables; submitted to Phys. Rev.

    Activity in Both Hippocampus and Perirhinal Cortex Predicts the Memory Strength of Subsequently Remembered Information

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    SummaryIt has been suggested that hippocampal activity predicts subsequent recognition success when recognition decisions are based disproportionately on recollection, whereas perirhinal activity predicts recognition success when decisions are based primarily on familiarity. Another perspective is that both hippocampal and perirhinal activity are predictive of overall memory strength. We tested the relationship between brain activity during learning and subsequent memory strength. Activity in a number of cortical regions (including regions within the “default network”) was negatively correlated with subsequent memory strength, suggesting that this activity reflects inattention or mind wandering (and, consequently, poor memory). In contrast, activity in both hippocampus and perirhinal cortex positively correlated with the subsequent memory strength of remembered items. This finding suggests that both structures cooperate during learning to determine the memory strength of what is being learned

    Functional consequences of sphingomyelinase-induced changes in erythrocyte membrane structure.

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    Inflammation enhances the secretion of sphingomyelinases (SMases). SMases catalyze the hydrolysis of sphingomyelin into phosphocholine and ceramide. In erythrocytes, ceramide formation leads to exposure of the removal signal phosphatidylserine (PS), creating a potential link between SMase activity and anemia of inflammation. Therefore, we studied the effects of SMase on various pathophysiologically relevant parameters of erythrocyte homeostasis. Time-lapse confocal microscopy revealed a SMase-induced transition from the discoid to a spherical shape, followed by PS exposure, and finally loss of cytoplasmic content. Also, SMase treatment resulted in ceramide-associated alterations in membrane-cytoskeleton interactions and membrane organization, including microdomain formation. Furthermore, we observed increases in membrane fragility, vesiculation and invagination, and large protein clusters. These changes were associated with enhanced erythrocyte retention in a spleen-mimicking model. Erythrocyte storage under blood bank conditions and during physiological aging increased the sensitivity to SMase. A low SMase activity already induced morphological and structural changes, demonstrating the potential of SMase to disturb erythrocyte homeostasis. Our analyses provide a comprehensive picture in which ceramide-induced changes in membrane microdomain organization disrupt the membrane-cytoskeleton interaction and membrane integrity, leading to vesiculation, reduced deformability, and finally loss of erythrocyte content. Understanding these processes is highly relevant for understanding anemia during chronic inflammation, especially in critically ill patients receiving blood transfusions

    Detection of Weld Defects by High Speed Imaging of the Vapor Plume

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    AbstractUsing two high speed cameras, we analyzed the 3D vapor plume fluctuations during laser welding of steel sheets in overlap configuration. Our results indicate that the position of the vapor plume contains relevant information on the process state. Whereas an increase of the penetration depth shifts the plume position in negative welding direction, welding defects like spatter formation or holes in the weld seam cause strong fluctuations of the plume position laterally transverse to the welding direction
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