6 research outputs found
Breakdowns' Diagnosis of A New Character Three-Phase High Voltage Power Supply for Industrial Microwave Generators with N=2 Magnetrons per Phase
This paper treats the modelisation of a new three phase character high voltage supply (HV) for industrial microwave generators with N=2 magnetrons per phase. This alimentation is based on the presentation of an equivalent p circuit model of a newly dimensioned high voltage transformer. Each phase of the three phase system supplies two parallel cell voltage doublers and current stabilizer. Each of these cells in turn supplies one magnetron 800Watts / 2.45GHz. This power supply is a star connection of three identical models of the single-phase power for N=2 magnetrons. The simulation under EMTP (Electro Magnetic Transients Program) in nominal conditions allows concluding that theoretical results are adjacent to the experimental measurements. Furthermore, a failure study of six magnetron of the microwave generator is also processed. The results permit to observe that the interaction between magnetrons dosn’t influence the nominal operation of the system
Modeling of three-limb three-phase transformer relates to shunt core using in industrial microwave generators with n=2 magnetron per phase
This paper describes the development and implementation of a digital simulation model of a three-phase transformer relates to shunt core transformer, which used to drive magnetron tubes in the microwave. The focus of this study is based on modeling of a new shell-type of three limbs three-phase transformer. The model uses to feed two magnetrons instead of one magnetron per phase. The proposed model is established on the simultaneous analysis of a duo electromagnetic lumped component equivalent circuit. This latter was implemented in a MATLAB environment under rated conditions. The results obtained from the application of the analytical method are provided results in conformity to the experimental tests in the case of single phase high voltage power supply for one magnetron
Effects of Once-Weekly Exenatide on Cardiovascular Outcomes in Type 2 Diabetes.
Abstract
BACKGROUND:
The cardiovascular effects of adding once-weekly treatment with exenatide to usual care in patients with type 2 diabetes are unknown.
METHODS:
We randomly assigned patients with type 2 diabetes, with or without previous cardiovascular disease, to receive subcutaneous injections of extended-release exenatide at a dose of 2 mg or matching placebo once weekly. The primary composite outcome was the first occurrence of death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke. The coprimary hypotheses were that exenatide, administered once weekly, would be noninferior to placebo with respect to safety and superior to placebo with respect to efficacy.
RESULTS:
In all, 14,752 patients (of whom 10,782 [73.1%] had previous cardiovascular disease) were followed for a median of 3.2 years (interquartile range, 2.2 to 4.4). A primary composite outcome event occurred in 839 of 7356 patients (11.4%; 3.7 events per 100 person-years) in the exenatide group and in 905 of 7396 patients (12.2%; 4.0 events per 100 person-years) in the placebo group (hazard ratio, 0.91; 95% confidence interval [CI], 0.83 to 1.00), with the intention-to-treat analysis indicating that exenatide, administered once weekly, was noninferior to placebo with respect to safety (P<0.001 for noninferiority) but was not superior to placebo with respect to efficacy (P=0.06 for superiority). The rates of death from cardiovascular causes, fatal or nonfatal myocardial infarction, fatal or nonfatal stroke, hospitalization for heart failure, and hospitalization for acute coronary syndrome, and the incidence of acute pancreatitis, pancreatic cancer, medullary thyroid carcinoma, and serious adverse events did not differ significantly between the two groups.
CONCLUSIONS:
Among patients with type 2 diabetes with or without previous cardiovascular disease, the incidence of major adverse cardiovascular events did not differ significantly between patients who received exenatide and those who received placebo. (Funded by Amylin Pharmaceuticals; EXSCEL ClinicalTrials.gov number, NCT01144338 .)
Failures’ Study of a New Character Three-Phase High Voltage Supply for industrial Microwave Generators with one magnetrons per Phase
This article treats the development of one of the equivalent electrical models for a single phase power supply for one
magnetron; in particular that of its own high voltage (HV) transformer newly dimensioned. This single phase system supplies
a voltage doubler and current stabilizer circuit, which supplies a single magnetron. Then, by star connecting the three identical
models of the single-phase power supply for one magnetron, we obtain a new character three-phase high voltage power
supply for industrial microwave generators with one magnetron per phase. The simulation with EMTP (Electro Magnetic
Transcients Program) in nominal operation has given the theoretical results close to the experimental measurements. Finally,
the magnetrons’ failure of the microwave generator was also treated and allowed to observe the interaction’s influence
between magnetrons; also the regulation of the anode current has been achieved successfully
Effects of once-weekly exenatide on cardiovascular outcomes in type 2 diabetes
BACKGROUND: The cardiovascular effects of adding once-weekly treatment with exenatide to usual care in patients with type 2 diabetes are unknown. METHODS: We randomly assigned patients with type 2 diabetes, with or without previous cardiovascular disease, to receive subcutaneous injections of extended-release exenatide at a dose of 2 mg or matching placebo once weekly. The primary composite outcome was the first occurrence of death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke. The coprimary hypotheses were that exenatide, administered once weekly, would be noninferior to placebo with respect to safety and superior to placebo with respect to efficacy. RESULTS: In all, 14,752 patients (of whom 10,782 [73.1%] had previous cardiovascular disease) were followed for a median of 3.2 years (interquartile range, 2.2 to 4.4). A primary composite outcome event occurred in 839 of 7356 patients (11.4%; 3.7 events per 100 person-years) in the exenatide group and in 905 of 7396 patients (12.2%; 4.0 events per 100 person-years) in the placebo group (hazard ratio, 0.91; 95% confidence interval [CI], 0.83 to 1.00), with the intention-to-treat analysis indicating that exenatide, administered once weekly, was noninferior to placebo with respect to safety (P<0.001 for noninferiority) but was not superior to placebo with respect to efficacy (P=0.06 for superiority). The rates of death from cardiovascular causes, fatal or nonfatal myocardial infarction, fatal or nonfatal stroke, hospitalization for heart failure, and hospitalization for acute coronary syndrome, and the incidence of acute pancreatitis, pancreatic cancer, medullary thyroid carcinoma, and serious adverse events did not differ significantly between the two groups. CONCLUSIONS: Among patients with type 2 diabetes with or without previous cardiovascular disease, the incidence of major adverse cardiovascular events did not differ significantly between patients who received exenatide and those who received placebo