1,954 research outputs found

    Quintessential Inflation in a thawing realization

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    We study quintessential inflation with an inverse hyperbolic type potential V(ϕ)=V0/cosh(ϕn/λn)V(\phi) = {V_0}/{\cosh \left( {\phi^n}/{\lambda^n} \right)}, where V0V_0, λ\lambda and "n" are parameters of the theory. We obtain a bound on λ\lambda for different values of the parameter n. The spectral index and the tensor-to-scalar-ratio fall in the 1σ1 \sigma bound given by the Planck 2015 data for n5n \geq 5 for certain values of λ\lambda. However for 3n<53 \leq n < 5 there exist values of λ\lambda for which the spectral index and the tensor-to-scalar-ratio fall only within the 2σ2 \sigma bound of the Planck data. Furthermore, we show that the scalar field with the given potential can also give rise to late time acceleration if we invoke the coupling to massive neutrino matter. We also consider the instant preheating mechanism with Yukawa interaction and put bounds on the coupling constants for our model using the nucleosynthesis constraint on relic gravity waves produced during inflation.Comment: 11 page

    Study of drug utilization trends in respiratory tract infections in a tertiary care teaching hospital: a retrospective study

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    Background: Drug utilization studies play crucial role in the health sector and ultimately it provides insight into the efficiency of drug use and results of such research can be used to help to set priorities for the rational use of medicines and allocation of health care budgets. Respiratory tract infections (RTIs) contributing to significant mortality and morbidity of populations especially in developing countries like India. Polypharmacy and irrational prescription are significant negative fallouts in treatment of RTIs. Keeping in view of this, our study was undertaken to analyze the drug utilization pattern of RTIs.Methods: The study was conducted at Gandhi Hospital, after obtaining permission from the Institutional Ethics Committee. We have collected data of 600 case records of the patients diagnosed with respiratory tract infection and evaluated for prescribing patterns in consonance with WHO indicators.Results: Out of the total case records 348 (58%) were of male patients and 252 (42%) of female patients. Age wise distribution was done; 79 (13.16%) 0-15 years, 46 (7.67%) 16-30 years, 123 (20.50%) 31-45 years, 194 (32.33%) 46-60 years and 158 (26.33%) patients belongs to >60 years of age group respectively. A total of 4682 drugs were prescribed, 2468 (52.71%) antibiotics, 768 (16.4%) bronchodilators, 581 (12.4%) corticosteroids, 323 (6.89%) antacids, 542 (11.57%) in miscellaneous category respectively. With regard to formulations 2463 (52.60%) oral, 1463 (31.24%) injectable and 756 (16.14%) inhalational drugs were prescribed. Numbers of Fixed dose combinations were 712 (15.20%). 7.8 drugs were prescribed per prescription. 2493 (53.24%) drugs were prescribed from National Essential Medicine List. 4168 (89.02%) drugs were prescribed by their brand names.Conclusions: Prescription of drugs with branded names, Irrational prescribing, poly pharmacy were observed in our study. So there is an urgent need for creating awareness among the health care professionals regarding rational prescription by using data from from drug utilization studies.
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