8 research outputs found
Emollient structure and chemical functionality effects on the biomechanical function of human stratum corneum
Keratin-water-NMF interaction as a three layer model in the human stratum corneum using in vivo confocal Raman microscopy
Irrigation Regimes on Growth and Metabolic Processes of Enterolobium contortisiliquum Seedlings
Indicators of skin barrier integrity among newborns massaged with mustard oil in rural Nepal
Mechanistic Evaluation of Hydration Effects on the Human Epidermal Permeation of Salicylate Esters
Association of dry skin with intercellular lipid composition of stratum corneum after erlotinib administration
Multiscale characterization of skin mechanics through in situ imaging
International audienceThe complex mechanical properties of skin have been studied intensively over the past decades. They are intrinsically linked to the structure of the skin at several length scales, from the macroscopic layers (epidermis, dermis and hypodermis) down to the microstructural organization at the molecular level. Understanding the link between this microscopic organization and the mechanical properties is of significant interest in the cosmetic and medical fields. Nevertheless, it only recently became possible to directly visualize the skinâs microstructure during mechanical assays, carried out on the whole tissue or on isolated layers. These recent observations have provided novel information on the role of structural components of the skin in its mechanical properties, mainly the collagen fibers in the dermis, while the contribution of others, such as elastin fibers, remains elusive. In this chapter we present current methods used to observe skinâs microstructure during a mechanical assay, along with their strengths and limitations, and we review the unique information they provide on the link between structure and function of the skin