Tetrakis(trimethylsilyloxy)silane for nanostructured SiO2-like films deposited by PECVD at atmospheric pressure

We performed the thin films deposition using atmospheric pressure plasma enhanced chemical vapour deposition (AP-PECVD) by means of a radiofrequency and a microwave plasma jets operating with mixtures of argon and tetrakis(trimethylsilyloxy)silane (TTMS)

Performance comparison of four exome capture systems for deep sequencing

Background Recent developments in deep (next-generation) sequencing technologies are significantly impacting medical research. The global analysis of protein coding regions in genomes of interest by whole exome sequencing is a widely used application. Many technologies for exome capture are commercially available; here we compare the performance of four of them: NimbleGen’s SeqCap EZ v3.0, Agilent’s SureSelect v4.0, Illumina’s TruSeq Exome, and Illumina’s Nextera Exome, all applied to the same human tumor DNA sample. Results Each capture technology was evaluated for its coverage of different exome databases, target coverage efficiency, GC bias, sensitivity in single nucleotide variant detection, sensitivity in small indel detection, and technical reproducibility. In general, all technologies performed well; however, our data demonstrated small, but consistent differences between the four capture technologies. Illumina technologies cover more bases in coding and untranslated regions. Furthermore, whereas most of the technologies provide reduced coverage in regions with low or high GC content, the Nextera technology tends to bias towards target regions with high GC content. Conclusions We show key differences in performance between the four technologies. Our data should help researchers who are planning exome sequencing to select appropriate exome capture technology for their particular application

Boundedness of the Maximal and Singular Operators on Generalized Orlicz-Morrey Spaces

Workshop on Operator Theory, Operator Algebras and Applications (WOAT) -- SEP 11-14, 2012 -- Univ Lisboa, Inst Super Tecnico, Lisbon, PORTUGALWOS: 000434317900007We consider generalized Orlicz-Morrey spaces MF Phi,phi(R-n) including their weak versions. In these generalized spaces we prove the boundedness of the Hardy-Littlewood maximal operator and Calderon-Zygmund singular operators with standard kernel. In all the cases the conditions for the boundedness are given either in terms of Zygmund- type integral inequalities on phi(r) without assuming any monotonicity property of phi(r), or in terms of supremal operators, related to phi(r).Ctr Funct Anal & Applicat, Portuguese Fdn Sci & TechnolAhi Evran University Scientific Research ProjectsAhi Evran University [PYO.FEN.4003.13.003]The research of F. Deringoz was partially supported by the grant of Ahi Evran University Scientific Research Projects (PYO.FEN.4003.13.003).; The research of V. Guliyev was partially supported by the grant of Ahi Evran University Scientific Research Projects (PYO.FEN.4003.13.003)