Development of an intense positron source using a crystal--amorphous hybrid target for linear colliders

In a conventional positron source driven by a few GeV electron beam, a high amount of heat is loaded into a positron converter target to generate intense positrons required by linear colliders, and which would eventually damage the converter target. A hybrid target, composed of a single crystal target as a radiator of intense gamma--rays, and an amorphous converter target placed downstream of the crystal, was proposed as a scheme which could overcome the problem.This paper describes the development of an intense positron source with the hybrid target. A series of experiments on positron generation with the hybrid target has been carried out with a 8--GeV electron beam at the KEKB linac. We observed that positron yield from the hybrid target increased when the incident electron beam was aligned to the crystal axis and exceeded the one from the conventional target with the converter target of the same thickness, when its thickness is less than about 2 radiation length. The measurements in the temperature rise of the amorphous converter target was successfully carried out by use of thermocouples. These results lead to establishment to the evaluation of the hybrid target as an intense positron source.Comment: 17pages, 10figure

Three Dimensional Structures of Particles Recovered from the Asteroid Itokawa by the Hayabusa Mission and a Role of X-Ray Microtomography in the Preliminary Examination

Particles of regolith on S-type Asteroid 25143 Itokawa were successfully recovered by the Hayabusa mission of JAXA (Japan Aerospace Exploration Agency). Near-infrared spectral study of Itokawa s surface indicates that these particles are materials similar to LL5 or LL6 chondrites. High-resolution images of Itokawa's surface suggest that they may be breccias and some impact products. At least more than 1500 particles were identified as Itokawa origin at curation facility of JAXA. Preliminary analysis with SEM/EDX at the curation facility shows that they are roughly similar to LL chondrites. Although most of them are less than 10 micron in size, some larger particles of about 100 micron or larger were also identified. A part of the sample (probably several tens particles) will be selected by Hayabusa sample curation team, and sequential examination will start from January 2011 by Hayabusa Asteroidal Sample Preliminary Examination Team (HASPET). In mainstream of the analytical flow, each particle will be examined by microtomography, XRD and XRF first as nondestructive analyses, and then the particle will be cut by an ultra-microtome and examined by TEM, SEM, EPMA, SIMS, PEEM/XANES, and TOF-SIMS sequentially. Three-dimensional structures of Itokawa particles will be obtained by microtomography sub-team of HASPET. The results together with XRD and XRF will be used for design of later destructive analyses, such as determination of cutting direction and depth, to obtain as much information as possible from small particles. Scientific results and a role of the microtomography in the preliminary examination will be presented

Measuring airway surface liquid depth in ex vivo mouse airways by X-ray imaging for the assessment of cystic fibrosis airway therapies

In the airways of those with cystic fibrosis (CF), the leading pathophysiological hypothesis is that an ion channel defect results in a relative decrease in airway surface liquid (ASL) volume, producing thick and sticky mucus that facilitates the establishment and progression of early fatal lung disease. This hypothesis predicts that any successful CF airway treatment for this fundamental channel defect should increase the ASL volume, but up until now there has been no method of measuring this volume that would be compatible with in vivo monitoring. In order to accurately monitor the volume of the ASL, we have developed a new x-ray phase contrast imaging method that utilizes a highly attenuating reference grid. In this study we used this imaging method to examine the effect of a current clinical CF treatment, aerosolized hypertonic saline, on ASL depth in ex vivo normal mouse tracheas, as the first step towards non-invasive in vivo ASL imaging. The ex vivo tracheas were treated with hypertonic saline, isotonic saline or no treatment using a nebuliser integrated within a small animal ventilator circuit. Those tracheas exposed to hypertonic saline showed a transient increase in the ASL depth, which continued for nine minutes post-treatment, before returning to baseline by twelve minutes. These findings are consistent with existing measurements on epithelial cell cultures, and therefore suggest promise for the future development of in vivo testing of treatments. Our grid-based imaging technique measures the ASL depth with micron resolution, and can directly observe the effect of treatments expected to increase ASL depth, prior to any changes in overall lung health. The ability to non-invasively observe micron changes in the airway surface, particularly if achieved in an in vivo setting, may have potential in pre-clinical research designed to bring new treatments for CF and other airway diseases to clinical trials.Kaye S. Morgan, Martin Donnelley, David M. Paganin, Andreas Fouras, Naoto Yagi, Yoshio Suzuki, Akihisa Takeuchi, Kentaro Uesugi, Richard C. Boucher, David W. Parsons, Karen K. W. Si

Cosmology and two-body problem of D-branes

In this paper, we investigate the dynamics and the evolution of the scale factor of a probe Dp-brane which move in the background of source Dp-branes. Action of the probe brane is described by the Born-Infeld action and the interaction with the background R-R field. When the probe brane moves away from the source branes, it expands by power law, whose index depends on the dimension of the brane. If the energy density of the gauge field on the brane is subdominant, the expansion is decelerating irrespective of the dimension of the brane. On the other hand, when the probe brane is a Nambu-Goto brane, the energy density of the gauge field can be dominant, in which case accelerating expansion occurs for $p \leq 4$. The accelerating expansion stops when the brane has expanded sufficiently so that the energy density of the gauge field become subdominant.Comment: 6 pages, 7 figures, reference added, accepted for publication in PR