395 research outputs found
Estimating input parameters from intracellular recordings in the Feller neuronal model
We study the estimation of the input parameters in a Feller neuronal model from a trajectory of the membrane potential sampled at discrete times. These input parameters are identified with the drift and the infinitesimal variance of the underlying stochastic diffusion process with multiplicative noise. The state space of the process is restricted from below by an inaccessible boundary. Further, the model is characterized by the presence of an absorbing threshold, the first hitting of which determines the length of each trajectory and which constrains the state space from above. We compare, both in the presence and in the absence of the absorbing threshold, the efficiency of different known estimators. In addition, we propose an estimator for the drift term, which is proved to be more efficient than the others, at least in the explored range of the parameters. The presence of the threshold makes the estimates of the drift term biased, and two methods to correct it are proposed
Turbulent spectrum of the Earth's ozone field
The Total Ozone Mapping Spectrometer (TOMS) database is subjected to an
analysis in terms of the Karhunen-Loeve (KL) empirical eigenfunctions. The
concentration variance spectrum is transformed into a wavenumber spectrum, . In terms of wavenumber is shown to be in the
inverse cascade regime, in the enstrophy cascade regime with the
spectral {\it knee} at the wavenumber of barotropic instability.The spectrum is
related to known geophysical phenomena and shown to be consistent with physical
dimensional reasoning for the problem. The appropriate Reynolds number for the
phenomena is .Comment: RevTeX file, 4 pages, 4 postscript figures available upon request
from Richard Everson <[email protected]
Modeling of Transitional Channel Flow Using Balanced Proper Orthogonal Decomposition
We study reduced-order models of three-dimensional perturbations in
linearized channel flow using balanced proper orthogonal decomposition (BPOD).
The models are obtained from three-dimensional simulations in physical space as
opposed to the traditional single-wavenumber approach, and are therefore better
able to capture the effects of localized disturbances or localized actuators.
In order to assess the performance of the models, we consider the impulse
response and frequency response, and variation of the Reynolds number as a
model parameter. We show that the BPOD procedure yields models that capture the
transient growth well at a low order, whereas standard POD does not capture the
growth unless a considerably larger number of modes is included, and even then
can be inaccurate. In the case of a localized actuator, we show that POD modes
which are not energetically significant can be very important for capturing the
energy growth. In addition, a comparison of the subspaces resulting from the
two methods suggests that the use of a non-orthogonal projection with adjoint
modes is most likely the main reason for the superior performance of BPOD. We
also demonstrate that for single-wavenumber perturbations, low-order BPOD
models reproduce the dominant eigenvalues of the full system better than POD
models of the same order. These features indicate that the simple, yet accurate
BPOD models are a good candidate for developing model-based controllers for
channel flow.Comment: 35 pages, 20 figure
Extended Heat-Fluctuation Theorems for a System with Deterministic and Stochastic Forces
Heat fluctuations over a time \tau in a non-equilibrium stationary state and
in a transient state are studied for a simple system with deterministic and
stochastic components: a Brownian particle dragged through a fluid by a
harmonic potential which is moved with constant velocity. Using a Langevin
equation, we find the exact Fourier transform of the distribution of these
fluctuations for all \tau. By a saddle-point method we obtain analytical
results for the inverse Fourier transform, which, for not too small \tau, agree
very well with numerical results from a sampling method as well as from the
fast Fourier transform algorithm. Due to the interaction of the deterministic
part of the motion of the particle in the mechanical potential with the
stochastic part of the motion caused by the fluid, the conventional heat
fluctuation theorem is, for infinite and for finite \tau, replaced by an
extended fluctuation theorem that differs noticeably and measurably from it. In
particular, for large fluctuations, the ratio of the probability for absorption
of heat (by the particle from the fluid) to the probability to supply heat (by
the particle to the fluid) is much larger here than in the conventional
fluctuation theorem.Comment: 23 pages, 6 figures. Figures are now in color, Eq. (67) was corrected
and a footnote was added on the d-dimensional cas
Karhunen-Lo`eve Decomposition of Extensive Chaos
We show that the number of KLD (Karhunen-Lo`eve decomposition) modes D_KLD(f)
needed to capture a fraction f of the total variance of an extensively chaotic
state scales extensively with subsystem volume V. This allows a correlation
length xi_KLD(f) to be defined that is easily calculated from spatially
localized data. We show that xi_KLD(f) has a parametric dependence similar to
that of the dimension correlation length and demonstrate that this length can
be used to characterize high-dimensional inhomogeneous spatiotemporal chaos.Comment: 12 pages including 4 figures, uses REVTeX macros. To appear in Phys.
Rev. Let
Assembling and Validating Data from Multiple Sources to Study Care for Veterans with Bladder Cancer
Despite the high prevalence of bladder cancer, research on optimal bladder cancer care is limited. One way to advance observational research on care is to use linked data from multiple sources. Such big data research can provide real-world details of care and outcomes across a large number of patients. We assembled and validated such data including (1) administrative data from the Department of Veterans Affairs (VA), (2) Medicare claims, (3) data abstracted by tumor registrars, (4) data abstracted via chart review from the national electronic health record, and (5) full text pathology reports
On dimension reduction in Gaussian filters
A priori dimension reduction is a widely adopted technique for reducing the
computational complexity of stationary inverse problems. In this setting, the
solution of an inverse problem is parameterized by a low-dimensional basis that
is often obtained from the truncated Karhunen-Loeve expansion of the prior
distribution. For high-dimensional inverse problems equipped with smoothing
priors, this technique can lead to drastic reductions in parameter dimension
and significant computational savings.
In this paper, we extend the concept of a priori dimension reduction to
non-stationary inverse problems, in which the goal is to sequentially infer the
state of a dynamical system. Our approach proceeds in an offline-online
fashion. We first identify a low-dimensional subspace in the state space before
solving the inverse problem (the offline phase), using either the method of
"snapshots" or regularized covariance estimation. Then this subspace is used to
reduce the computational complexity of various filtering algorithms - including
the Kalman filter, extended Kalman filter, and ensemble Kalman filter - within
a novel subspace-constrained Bayesian prediction-and-update procedure (the
online phase). We demonstrate the performance of our new dimension reduction
approach on various numerical examples. In some test cases, our approach
reduces the dimensionality of the original problem by orders of magnitude and
yields up to two orders of magnitude in computational savings
Bottleneck effects in turbulence: Scaling phenomena in r- versus p-space
We (analytically) calculate the energy spectrum corresponding to various
experimental and numerical turbulence data analyzed by Benzi et al.. We find
two bottleneck phenomena: While the local scaling exponent of the
structure function decreases monotonically, the local scaling exponent
of the corresponding spectrum has a minimum of
at and a maximum
of at . A physical
argument starting from the constant energy flux in p--space reveals the general
mechanism underlying the energy pileups at both ends of the p--space scaling
range. In the case studied here, they are induced by viscous dissipation and
the reduced spectral strength on the scale of the system size, respectively.Comment: 9 pages, 3figures on reques
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