2,787 research outputs found
Generalized Gravi-Electromagnetism
A self consistant and manifestly covariant theory for the dynamics of four
charges (masses) (namely electric, magnetic, gravitational, Heavisidian) has
been developed in simple, compact and consistent manner. Starting with an
invariant Lagrangian density and its quaternionic representation, we have
obtained the consistent field equation for the dynamics of four charges. It has
been shown that the present reformulation reproduces the dynamics of individual
charges (masses) in the absence of other charge (masses) as well as the
generalized theory of dyons (gravito - dyons) in the absence gravito - dyons
(dyons). key words: dyons, gravito - dyons, quaternion PACS NO: 14.80H
A note on a local ergodic theorem for an infinite tower of coverings
This is a note on a local ergodic theorem for a symmetric exclusion process
defined on an infinite tower of coverings, which is associated with a finitely
generated residually finite amenable group.Comment: Final version to appear in Springer Proceedings in Mathematics and
Statistic
Maxwell equations in matrix form, squaring procedure, separating the variables, and structure of electromagnetic solutions
The Riemann -- Silberstein -- Majorana -- Oppenheimer approach to the Maxwell
electrodynamics in vacuum is investigated within the matrix formalism. The
matrix form of electrodynamics includes three real 4 \times 4 matrices. Within
the squaring procedure we construct four formal solutions of the Maxwell
equations on the base of scalar Klein -- Fock -- Gordon solutions. The problem
of separating physical electromagnetic waves in the linear space
\lambda_{0}\Psi^{0}+\lambda_{1}\Psi^{1}+\lambda_{2}\Psi^{2}+ lambda_{3}\Psi^{3}
is investigated, several particular cases, plane waves and cylindrical waves,
are considered in detail.Comment: 26 pages 16 International Seminar NCPC, May 19-22, 2009, Minsk,
Belaru
Age-related changes to the neural correlates of working memory which emerge after midlife
Previous research has indicated that the neural processes which underlie working memory change with age. Both age-related increases and decreases to cortical activity have been reported. This study investigated which stages of working memory are most vulnerable to age-related changes after midlife. To do this we examined age-differences in the 13 Hz steady state visually evoked potential (SSVEP) associated with a spatial working memory delayed response task. Participants were 130 healthy adults separated into a midlife (40-60 years) and an older group (61-82 years). Relative to the midlife group, older adults demonstrated greater bilateral frontal activity during encoding and this pattern of activity was related to better working memory performance. In contrast, evidence of age-related under activation was identified over left frontal regions during retrieval. Findings from this study suggest that after midlife, under-activation of frontal regions during retrieval contributes to age-related decline in working memory performance. © 2014 Macpherson, White, Ellis, Stough, Camfield, Silberstein and Pipingas
Botulinum toxin type A in the prophylactic treatment of chronic tension-type headache: A multicentre, double-blind, randomized, placebo-controlled, parallel-group study
We studied the safety and efficacy of 0 U, 50 U, 100 U, 150 U (five sites), 86 Usub and 100 Usub (three sites) botulinum toxin type A (BoNTA; BOTOX); Allergan, Inc., Irvine, CA, USA) for the prophylaxis of chronic tension-type headache (CTTH). Three hundred patients (62.3% female; mean age 42.6 years) enrolled. For the primary endpoint, the mean change from baseline in the number of TTH-free days per month, there was no statistically significant difference between placebo and four BoNTA groups, but a significant difference favouring placebo vs. BoNTA 150 was observed (4.5 vs. 2.8 tension headache-free days/month; P = 0.007). All treatment groups improved at day 60. Although efficacy was not demonstrated for the primary endpoint, at day 90, more patients in three BoNTA groups had \u3eor=50% decrease in tension headache days than did placebo (
Generalized iterated wreath products of symmetric groups and generalized rooted trees correspondence
Consider the generalized iterated wreath product of symmetric groups. We give a complete description of the traversal
for the generalized iterated wreath product. We also prove an existence of a
bijection between the equivalence classes of ordinary irreducible
representations of the generalized iterated wreath product and orbits of labels
on certain rooted trees. We find a recursion for the number of these labels and
the degrees of irreducible representations of the generalized iterated wreath
product. Finally, we give rough upper bound estimates for fast Fourier
transforms.Comment: 18 pages, to appear in Advances in the Mathematical Sciences. arXiv
admin note: text overlap with arXiv:1409.060
The percent of chronic migraine patients who responded to onabotulinumtoxinA treatment per treatment cycle in the PREEMPT clinical program
Favorable outcome of early treatment of new onset child and adolescent migraine-implications for disease modification.
There is evidence that the prevalence of migraine in children and adolescents may be increasing. Current theories of migraine pathophysiology in adults suggest activation of central cortical and brainstem pathways in conjunction with the peripheral trigeminovascular system, which ultimately results in release of neuropeptides, facilitation of central pain pathways, neurogenic inflammation surrounding peripheral vessels, and vasodilatation. Although several risk factors for frequent episodic, chronic, and refractory migraine have been identified, the causes of migraine progression are not known. Migraine pathophysiology has not been fully evaluated in children. In this review, we will first discuss the evidence that early therapeutic interventions in the child or adolescent new onset migraineur, may halt or limit progression and disability. We will then review the evidence suggesting that many adults with chronic or refractory migraine developed their migraine as children or adolescents and may not have been treated adequately with migraine-specific therapy. Finally, we will show that early, appropriate and optimal treatment of migraine during childhood and adolescence may result in disease modification and prevent progression of this disease
Generalized iterated wreath products of cyclic groups and rooted trees correspondence
Consider the generalized iterated wreath product where . We
prove that the irreducible representations for this class of groups are indexed
by a certain type of rooted trees. This provides a Bratteli diagram for the
generalized iterated wreath product, a simple recursion formula for the number
of irreducible representations, and a strategy to calculate the dimension of
each irreducible representation. We calculate explicitly fast Fourier
transforms (FFT) for this class of groups, giving literature's fastest FFT
upper bound estimate.Comment: 15 pages, to appear in Advances in the Mathematical Science
Ketamine for Refractory Headache: A Retrospective Analysis.
BACKGROUND AND OBJECTIVES: The burden of chronic headache disorders in the United States is substantial. Some patients are treatment refractory. Ketamine, an N-methyl-D-aspartate antagonist, provides potent analgesia in subanesthetic doses in chronic pain, and limited data suggest it may alleviate headache in some patients.
METHODS: We performed a retrospective study of 61 patients admitted over 3 years for 5 days of intravenous therapy that included continuous ketamine to determine responder rate and patient and ketamine infusion characteristics. Pain ratings at 2 follow-up visits were recorded. An immediate responder was a patient with decrease of 2 points or greater in the numerical rating scale (0-10) from start to final pain in the hospital. Sustained response at office visits 1 and 2 was determined based on maintaining the 2-point improvement at those visits. Patients were assessed daily for pain and adverse events (AEs).
RESULTS: Forty-eight (77%) of the 61 patients were immediate responders. There were no differences regarding demographics, opioid use, or fibromyalgia between immediate responders and nonresponders. Maximum improvement occurred 4.56 days (mean) into treatment. Sustained response occurred in 40% of patients at visit 1 (mean, 38.1 days) and 39% of patients at visit 2 (mean, 101.3 days). The mean maximum ketamine rate was 65.2 ± 2.8 mg/h (0.76 mg/kg per hour). Ketamine rates did not differ between groups. Adverse events occurred equally in responders and nonresponders and were mild.
CONCLUSIONS: Ketamine was associated with short-term analgesia in many refractory headache patients with tolerable adverse events. A prospective study is warranted to confirm this and elucidate responder characteristics
- …
