Phytotoxic Effect to Cockscomb (Celosia cristata L.) with Response of Chlorpyrifos Treatments

The present work was conducted to evaluate the phytotoxic of chlorpyrifos on cockscomb (Celosia cristata L.) plant.  The seeds was exposed different dosage (control, 0.5, 1, 2 and 2.5%) of chlorpyrifos. On the 7th day seed germination percentage were determined, seedling morphological such as shoot length, root length, biomass and photosynthetic pigments like chlorophyll ‘a’ and chlorophyll ‘b’ were examined on 30, 60 and 90 days after treatments. The germination percentage negatively affect with increasing chlorpyrifos level. The morphological and photosynthetic pigments were increases at optimum level (0.5%). Moreover, above the optimum concentration all investigated parameters was decreased with increasing chlorpyrifos level. The obtained results suggest that usage of this insecticide optimum dosage helpful for good agricultural practices

Metastasis-Associated protein 1 is an upstream regulator of DNMT3a and stimulator of insulin-growth factor binding protein-3 in breast cancer.

Despite a recognized role of DNA methyltransferase 3a (DNMT3a) in human cancer, the nature of its upstream regulator(s) and relationship with the master chromatin remodeling factor MTA1, continues to be poorly understood. Here, we found an inverse relationship between the levels of MTA1 and DNMT3a in human cancer and that high levels of MTA1 in combination of low DNMT3a status correlates well with poor survival of breast cancer patients. We discovered that MTA1 represses DNMT3a expression via HDAC1/YY1 transcription factor complex. Because IGFBP3 is an established target of DNMT3a, we investigated the effect of MTA1 upon IGFBP3 expression, and found a coactivator role of MTA1/c-Jun/Pol II coactivator complex upon the IGFBP3 transcription. In addition, MTA1 overexpression correlates well with low levels of DNMT3a which, in turn also correlates with a high IGFBP3 status in breast cancer patients and predicts a poor clinical outcome for breast cancer patients. These findings suggest that MTA1 could regulate the expression of IGFBP3 in both DNMT3a-dependent and -independent manner. Together findings presented here recognize an inherent role of MTA1 as a modifier of DNMT3a and IGFBP3 expression, and consequently, the role of MTA1-DNMT3a-IGFBP3 axis in breast cancer progression

Antibacterial Effect of Green Synthesized Silver Nanoparticles using Cineraria maritima

Nanoparticles display entirely novel physicochemical characteristics for specific applications because of their exceptional size and shape. Owing to the present study, we reported biosynthesis, characterization and antibacterial properties of Cineraria maritima (Cm) assisted silver nanoparticles (Ag NPs). The surface plasmon vibration, crystalline structure, surface morphology, elemental composition, and possible functional molecules vibration of prepared Cm-Ag NPs were characterized by different instrumentation techniques. The spectrum of UV-Vis of Cm-Ag NPs showed maximum plasma intensity occurred around 425nm. XRD spectrum showed the face-centred cubic (FCC) nature of Cm-Ag NPs. The SEM image of the Cm-Ag NPs demonstrated a predominantly spherical shape with cluster formation of small particles to large particles with sizes ranging from 21.57 nm to 39.16 nm. EDS spectrum indicated the existence of Ag elements in Cm-Ag NPs. FTIR intense peaks of Cm-Ag NPs showed the different functional molecules such as phenol, alkene, aldehydes, and a carbonyl group. In addition, Cm-Ag NPs coated textile cotton fabric sample showed substantial anti-bacterial properties against a tested bacterial pathogen

Marker-Assisted Breeding as Next-Generation Strategy for Genetic Improvement of Productivity and Quality: Can It Be Realized in Cotton?

The dawdling development in genetic improvement of cotton with conventional breeding program is chiefly due to lack of complete knowledge on and precise manipulation of fiber productivity and quality. Naturally available cotton continues to be a resource for the upcoming breeding program, and contemporary technologies to exploit the available natural variation are outlined in this paper for further improvement of fiber. Particularly emphasis is given to application, obstacles, and perspectives of marker-assisted breeding since it appears to be more promising in manipulating novel genes that are available in the cotton germplasm. Deployment of system quantitative genetics in marker-assisted breeding program would be essential to realize its role in cotton. At the same time, role of genetic engineering and in vitro mutagenesis cannot be ruled out in genetic improvement of cotton

Outgassing Behavior and Heat Treatment Optimization of JSC-1A Lunar Regolith Simulant

As NASA Strives towards a Long Duration Presence on the Moon, It Has Become Increasingly Important to Learn How to Better Utilize Resources from the Lunar Surface for Everything from Habitats, Vehicle Infrastructure, and Chemical Extraction. to that End, a Variety of Lunar Simulants Have Been Sourced from Terrestrially Available Volcanic Minerals and Glass as Apollo Regolith is Unavailable for Experimentation Needing Large Masses. However, While Mineralogy and Chemical Composition Can Approach that of Lunar Material in These Simulants, There Are Still Distinct Non-Lunar Phases Such as Hydrates, Carbonates, Sulfates, and Clays that Can Cause Simulants to Behave Distinctly Non-Lunar in a Variety of Processing Conditions that Maybe Applied In-Situ to Lunar Material. Notably, Severe Glassy Bubbling Has Been Documented in a Variety of Vacuum Sintering Experiments on JSC-1A Lunar Mare Simulant Heated Via Microwaves. the Origins of This Outgassing Have Not Been Well Understood But Are Normally Attributed to the Decomposition of Non-Lunar Contaminates Intrinsic to Virtually All Terrestrially Sourced Simulants. as Such, a Series of Controlled Environmental Tests Were Performed to Ascertain the Origins of the High Temperature Outgassing and to Develop Heat Treatments that Can Drive JSC-1A Closer to Lunar Composition and Behavior. It Was Found that in JSC-1A at Elevated Temperatures Distinct Gas Evolutions of Water, Carbon Dioxide, and Sulfur Dioxide Occur in Both Inert Gas and Vacuum. Additionally, the Presence of Hydrogen during Heat Treatments Was Shown to Dramatically Change Gas Evolutions, Leading to Distinctly More Lunar-Like Composition and Behavior from JSC-1A Simulant

Integrating Hydrogen Energy Storage into Urban Mobility Solutions

The transition to sustainable urban mobility solutions is imperative in the face of escalating environmental and health challenges. This paper reviews the work in the areas of decarbonizing power systems, urban mobility and transportation modes, and the integration of renewable energy in smart cities. The integration of renewable energy sources, such as wind and solar power, into power systems is pivotal for decarbonization. However, their intermittent nature poses challenges for high-level integration. Energy storage emerges as a crucial solution, with technologies like fuel cell vehicles, water electrolysis, and flow batteries playing significant roles. Urban mobility, dominated by internal combustion engines, has led to environmental degradation and health issues. Transitioning to cleaner transportation modes, integrating electric vehicle stations with renewable energy, and ensuring uninterrupted power supply are essential steps forward. Furthermore, the potential of smart cities harnessing non-dispatchable photovoltaic and wind power is vast. Yet, the challenge of large-scale energy storage remains. The concept of using renewable energy to produce hydrogen, which can then stabilize the grid, offers a promising avenue. This review underscores the importance of integrating hydrogen energy storage to revolutionize urban mobility solutions

WIRELESS WATER QUALITY MONITORING AND DETERIORATION PREDICTION SYSTEM

Water is an essential resource in day-to-day life. Pollution and urbanization have led to higher susceptibility of source water to contamination. There is a pressing need to develop a water quality monitoring system to preserve the quality of source water and ultimately safeguard human health. This proposes a low cost, wireless water quality monitoring system, wherein the quality of water stored in overhead tanks is continuously monitored. The quality of water is measured by parameters that are critical quality indicators. The data encompassing these parameters are stored in a Cloud database (in realtime) along with its timestamp. The quality of water is ascertained based on the comparison of the monitored data to standard well-established thresholds. The data, annotated with its timestamp is treated as a time-series. A univariate non-seasonal Auto Regressive Integrated Moving Average (ARIMA) model is employed to forecast individual water quality parameters. The results of forecasting are used to predict water quality deterioration. The model used is found to have mean square errors of 0.001 for pH, 0.076 for temperature and 0.001 for turbidity between the actual and forecasted values

αA-Crystallin Peptide 66SDRDKFVIFLDVKHF80 Accumulating in Aging Lens Impairs the Function of α-Crystallin and Induces Lens Protein Aggregation

The eye lens is composed of fiber cells that are filled with α-, β- and γ-crystallins. The primary function of crystallins is to maintain the clarity of the lens through ordered interactions as well as through the chaperone-like function of α-crystallin. With aging, the chaperone function of α-crystallin decreases, with the concomitant accumulation of water-insoluble, light-scattering oligomers and crystallin-derived peptides. The role of crystallin-derived peptides in age-related lens protein aggregation and insolubilization is not understood.We found that αA-crystallin-derived peptide, (66)SDRDKFVIFLDVKHF(80), which accumulates in the aging lens, can inhibit the chaperone activity of α-crystallin and cause aggregation and precipitation of lens crystallins. Age-related change in the concentration of αA-(66-80) peptide was estimated by mass spectrometry. The interaction of the peptide with native crystallin was studied by multi-angle light scattering and fluorescence methods. High molar ratios of peptide-to-crystallin were favourable for aggregation and precipitation. Time-lapse recordings showed that, in the presence of αA-(66-80) peptide, α-crystallin aggregates and functions as a nucleus for protein aggregation, attracting aggregation of additional α-, β- and γ-crystallins. Additionally, the αA-(66-80) peptide shares the principal properties of amyloid peptides, such as β-sheet structure and fibril formation.These results suggest that crystallin-derived peptides such as αA-(66-80), generated in vivo, can induce age-related lens changes by disrupting the structure and organization of crystallins, leading to their insolubilization. The accumulation of such peptides in aging lenses may explain a novel mechanism for age-related crystallin aggregation and cataractogenesis

Chitosan complements entrapment of silicon inside nitrogen doped carbon to improve and stabilize the capacity of Li-ion batteries

Abstract A facile strategy to entrap milled silicon (m-Si) particles using nitrogen-doped-carbon (N-C@m-Si) to overcome the dramatic volume changes in Si during intercalation of lithium ions and to improve its electronic conductivity is reported here. The only natural nitrogen containing biomaterial alkaline polysaccharide, i.e., chitosan, is used as the carbon source. Simple hydrothermal technique followed by a subsequent carbonization process is used to synthesize N-C and N-C@m-Si particles. N-C@m-Si exhibited significantly improved electrochemical performance as compared to bare m-Si, which is confirmed by the obtained discharge capacity of 942.4 mAh g−1 and columbic efficiency of 97% after 50 cycles at 0.1C rate. With regard to the N-C electrodes, the obtained discharge capacity of 485.34 mAh g−1 and columbic efficiency of 99.78%, after 50 cycles at 0.1C rate is superior to the commercial graphite electrodes. The solid electrolyte interphase (SEI) layer that formed over m-Si and N-C@m-Si electrodes is characterized using X-ray photoelectron spectroscopy. Compared to the SEI layer that formed over m-Si electrode after 10 charge-discharge cycles, the N-C@m-Si electrode had a stable lithium fluoride and carbonate species. Brief reaction mechanisms, representing the formation of different species in the SEI layer, is derived to explain its behavior during the electrochemical processes

Template-Assisted Synthesis and Characterization of Passivated Nickel Nanoparticles

Potential applications of nickel nanoparticles demand the synthesis of self-protected nickel nanoparticles by different synthesis techniques. A novel and simple technique for the synthesis of self-protected nickel nanoparticles is realized by the inter-matrix synthesis of nickel nanoparticles by cation exchange reduction in two types of resins. Two different polymer templates namely strongly acidic cation exchange resins and weakly acidic cation exchange resins provided with cation exchange sites which can anchor metal cations by the ion exchange process are used. The nickel ions which are held at the cation exchange sites by ion fixation can be subsequently reduced to metal nanoparticles by using sodium borohydride as the reducing agent. The composites are cycled repeating the loading reduction cycle involved in the synthesis procedure. X-Ray Diffraction, Scanning Electron Microscopy, Transmission Electron microscopy, Energy Dispersive Spectrum, and Inductively Coupled Plasma Analysis are effectively utilized to investigate the different structural characteristics of the nanocomposites. The hysteresis loop parameters namely saturation magnetization and coercivity are measured using Vibrating Sample Magnetometer. The thermomagnetization study is also conducted to evaluate the Curie temperature values of the composites. The effect of cycling on the structural and magnetic characteristics of the two composites are dealt in detail. A comparison between the different characteristics of the two nanocomposites is also provided