[Cu32(H)20{S2P(OiPr)2}12]: The Largest Number of Hydrides Recorded in a Molecular Nanocluster by Neutron Diffraction

[[sponsorship]]化學研究所[[note]]已出版;[SCI];有審查制度;具代表性[[note]]http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Drexel&SrcApp=hagerty_opac&KeyRecord=0947-6539&DestApp=JCR&RQ=IF_CAT_BOXPLO

Comparative Study of Properties of L-Histidine and L-Histidine Nickel Nitrate Hexahydrate Crystals Grown by Slow Evaporation

International audienceL-Histidine (LH) is an amino acid. It is an organic material. L-Histidine Nickel Nitrate Hexahydrate (LHNNH) is a semi organic material. It is a complex of bivalent nickel ion with L-Histidine amino acid. Complexes of bivalent metal ions with amino acids are generally good NLO materials. Crystals of L-Histidine and L-Histidine Nickel Nitrate Hexahydrate (LHNNH) have been successfully grown by slow evaporation method using water as solvent. The crystal structure and lattice parameters of LH and LHNNH are determined by Single crystal X-ray diffraction analysis. The functional groups in LH and LHNNH are confirmed by FTIR analysis. With the help of UV-Vis spectroscopy the optical band gap and optical transparency are studied. The chemical composition of LH and LHNNH are studied by CHN and EDAX analysis. Thermally stability and thermal phase transitions of LH and LHNNH are analyzed by TGA/DTA. The Second Harmonic Generation (SHG) efficiency of LH and LHNNH have been experimentally estimated. Introduction: L-Histidine is an optically active α-amino acid and is a tridentate ligand that has an imidazole ring, amino and carboxylate groups. Amino acids are the potential candidates for optical second harmonic generation because they contain chiral carbon atom and crystallize in non-centro symmetric space groups and it is an essential criterion for nonlinear application [1]. Amino acids are interesting materials for NLO applications. Complexes of amino acids with inorganic salts are promising materials for optical Second Harmonic Generation. In recent years semi organic crystals have emerged as extremely promising building blocks for NLO materials. They share the properties of both organic and inorganic materials. Amino acids are interesting materials for NLO applications, as they exhibit molecular chirality, absence of strongly conjugated bonds and zwitterionic nature of the molecule [2]

Detection of Bacillus subtilis spores using peptide-functionalized cantilever arrays

We move beyond anti body-antigen binding systems and demonstrate that short peptide ligands can be used to efficiently capture Bacillus subtilis (a simulant of Bacillus anthracis) spores in liquids. On an eight-cantilever array chip, four cantilevers were coated with binding peptide (NHFLPKV-GGGC) and the other four were coated with control peptide (LFNKHVP-GGGC) for reagentless detection of whole B. subtilis spores in liquids. The peptide-ligand-functionalized microcantilever chip was mounted onto a fluid cell filled with a B. subtilis spore suspension for similar to 40 min; a 40 nm net differential deflection was observed. Fifth-mode resonant frequency measurements were also performed before and after dipping microcantilever arrays into a static B. subtilis solution showing a substantial decrease in frequency for binding-peptide-coated microcantilevers as compared to that for control peptide cantilevers. Further confirmation was obtained by subsequent examination of the microcantilever arrays under a dark-field microscope. Applications of this technology will serve as a platform for the detection of pathogenic organisms including biowarfare agents

Targeting surface voids to counter membrane disorders in lipointoxication-related diseases.

Saturated fatty acids (SFA), which are abundant in the so-called western diet, have been shown to efficiently incorporate within membrane phospholipids and therefore impact on organelle integrity and function in many cell types. In the present study, we have developed a yeast-based two-step assay and a virtual screening strategy to identify new drugs able to counter SFA-mediated lipointoxication. The compounds identified here were effective in relieving lipointoxication in mammalian β-cells, one of the main targets of SFA toxicity in humans. In vitro reconstitutions and molecular dynamics simulations on bilayers revealed that these molecules, albeit according to different mechanisms, can generate voids at the membrane surface. The resulting surface defects correlate with the recruitment of loose lipid packing or void-sensing proteins required for vesicular budding, a central cellular process that is precluded under SFA accumulation. Taken together, the results presented here point at modulation of surface voids as a central parameter to consider in order to counter the impacts of SFA on cell function.This article is freely available from the publisher's site. Click on the Additional Link above to access the full-text

Nano-Heteroarchitectures of Two-Dimensional MoS₂@ One-Dimensional Brookite TiO₂ Nanorods: Prominent Electron Emitters for Displays

We report comparative field electron emission (FE) studies on a large-area array of two-dimensional MoS₂-coated @ one-dimensional (1D) brookite (β) TiO₂ nanorods synthesized on Si substrate utilizing hot-filament metal vapor deposition technique and pulsed laser deposition method, independently. The 10 nm wide and 760 nm long 1D β-TiO₂ nanorods were coated with MoS₂ layers of thickness ∼4 (±2), 20 (±3), and 40 (±3) nm. The turn-on field (<i>E</i>_on) of 2.5 V/μm required to a draw current density of 10 μA/cm² observed for MoS₂-coated 1D β-TiO₂ nanorods emitters is significantly lower than that of doped/undoped 1D TiO₂ nanostructures, pristine MoS₂ sheets, MoS₂@SnO₂, and TiO₂@MoS₂ heterostructure-based field emitters. The orthodoxy test confirms the viability of the field emission measurements, specifically field enhancement factor (β_FE) of the MoS₂@TiO₂/Si emitters. The enhanced FE behavior of the MoS₂@TiO₂/Si emitter can be attributed to the modulation of the electronic properties due to heterostructure and interface effects, in addition to the high aspect ratio of the vertically aligned TiO₂ nanorods. Furthermore, these MoS₂@TiO₂/Si emitters exhibit better emission stability. The results obtained herein suggest that the heteroarchitecture of MoS₂@β-TiO₂ nanorods holds the potential for their applications in FE-based nanoelectronic devices such as displays and electron sources. Moreover, the strategy employed here to enhance the FE behavior via rational design of heteroarchitecture structure can be further extended to improve other functionalities of various nanomaterials