Increasing Efficiency and Reliability in Multicast Routing based V2V Communication for Direction-Aware Cooperative Collision Avoidance

Mobile ad hoc networks (MANETs), which are a promising method for the intelligent transportation system, include vehicular ad hoc networks (VANETs) (ITS). Developing reliable and strong cooperative collision avoidance (CCA) strategy to mitigate the growing number of road fatalities each year is one of the main difficulties facing vehicular ad hoc networks (VANETs).A proper and successful routing method aids in the successful expansion of vehicular ad hoc networks. This study explains the architecture, interface layers, safety features, and implementation of a novel priority-based direction-aware collision avoidance system (P-DVCA). It distinguishes our study in the collision area of VANETs by accounting for realistic bi-directional traffic. The scheme begins with the development of dynamic clusters, which is difficult because of the bi-directional diverse traffic and the need to avoid collisions within and between clusters. The target node is sent an early warning message that includes the safe speed and the likelihood of a collision in order to notify it of an impending danger. To determine the least expensive, shortest one with the fewest hops between the source and the endpoint. A crucial problem with VANETs is the transmission of data from a source node to the base station. Cross-layer issues must be solved for a robust and stable collision avoidance programme to function properly in a VANET communication architecture. The results of the simulation show that the suggested scheme significantly outperforms CCM and C-RACCA in terms of cluster stability, fewer collisions, low latency, and low communication overhead. According to the findings, P-DVCA offers stable clustering, minimises network congestion, and lowers communication overhead and latency

Sum Rate Maximization and Consistency in D2D Communication Based on ACO and Game Theory

Cellular network is the most popular network setup among today’s wireless communication systems. The primary resource in a cellular system is the spectrum for communication, and owing to the rising number of cellular users, the spectrum that is currently accessible from different service providers is depleting quickly. The resource or channel allocation is the most hindering task in cellular networks. Many efforts have been taken by many researchers to allocate the resources properly in order to increase the channel utilization and it is found that one effective method for reusing the channels inside a cell is device to device (D2D) communication. D2D communication was first developed in order to achieve the fundamental goals of fast data rates, widespread coverage with little latency, energy efficiency, and low per-information transmission costs. The dynamic behaviour of this network set-up again increases the risk of different types of interferences, which is another issue faced by the researchers. In this paper an effort is taken to understand and solve various aspects of channel allocation and Cellular networks have incorporated interference management in D2D communication especially. The two major issues of allocation of resource and management of interference in D2D communication is addressed here. This paper considers the meta heuristic algorithm namely Ant Colony Optimization (ACO) for resource allocation issue and interference management. The sum rate maximization is achieved through Game theory along with the concept of resource exchange in turn to increase the consistency of D2D communication setup. The results demonstrate that our algorithm can significantly increase the sum rate of D2D pairs when compared to other algorithms suggested by related works

Radiation therapy for locally recurrent breast cancer.

Approximately one-third of all breast cancer patients experience local recurrence of their tumor after initial treatment. As initial treatment often employs the use of radiation therapy (RT), the standard of care for local breast cancer recurrence after initial breast conserving therapy has traditionally been surgical intervention with mastectomy. However, recent attempts to preserve the intact breast after recurrence with local excision have revealed a potential need for RT in addition to repeat breast conserving surgery as rates of local failure with resection alone remain high. Additionally, local recurrence following initial mastectomy and chest wall RT can be treated with reirradiation to increase local control. Repeating RT, however, in a previously irradiated area, is a complex treatment strategy, as the clinician must carefully balance maximizing treatment effectiveness while minimizing treatment-related toxicity. As a result, physicians have been hesitant to treat recurrent disease with repeat RT with limited data. Results from the current literature are promising and current clinical trials are underway to explore reirradiation modalities which will provide additional information on treatment-related toxicity and outcomes. This paper will review the current literature on repeat radiation therapy for locally recurrent breast cancer

Intrauterine insemination: a retrospective review on determinants of success

Background: To determine the prognostic factors such as female patient’s characteristics and of semen parameters on the pregnancy rate following intrauterine inseminationMethods: This study was done at Assisted Reproduction Centre, KLE’s Hospital and Medical Research Centre, Belgaum, India between June 2011 to May 2012. A total of 264 IUI cycles in which clomiphene citrate with or without human menopausal gonadotropin was used for ovarian stimulation were analysed retrospectively to identify prognostic factors regarding treatment outcome.Results: In this study the pregnancy rate was 17.25%. The logistic regression analysis of variables showed that number of follicles and total IUI cycles were significantly associated with success rate but age of the couple, duration of infertility, endometrial thickness, size of the follicles, sperm count and sperm motility did not show significant differences between pregnant and non pregnant women.Conclusions: The findings of this study showed that age of the couple, duration of infertility, endometrial thickness, size of the follicles, sperm count and sperm motility did not correlate with pregnancy occurrence in an IUI cycle but number of follicles and total IUI cycles correlated with the occurrence of pregnancy.

MRI Evaluation of Carotid Cavernous Fistula – A Case Report

A carotid cavernous fistula is a rare condition and often difficult to diagnose. We herewith present a case of a female patient who presented with minimal proptosis in the right eye and occipital headache. Magnetic resonance imaging showed classical findings like arterialization of ophthalmic veins and tortuous prominent cavernous sinuses on right side. In such situations, magnetic resonance venography (MRV) plays a major role in the diagnosis and may reveal any cerebral thrombosis. We will be discussing the types of CCF and the MRV findings which help in the diagnosis as well as treatment planning

Assessment of soil physical health and productivity of Kharkhoda and Gohana blocks of Sonipat district (Haryana), India

In order to assess soil health of Kharkhoda and Gohana blocks of Sonipat district (a part of western Yamuna canal irrigated region), important parameters namely pH, electrical conductivity (EC), texture, bulk density (BD), saturated hydraulic conductivity (HC), soil organic carbon (OC), available water retension capacity (AWRC) and non capillary pores (NCP) were measured by collecting undisturbed soil samples in nearly 66 villages. Soil physical rating index (PI) method was used to compute PI which was an indicator of soil physical health of thatregion. Results revealed that in Gohana and Kharkhoda blocks, nearly 90% area had pH <8.0 and EC>4 dS m-1, which indicated that soils were saline. Prediction maps of soil BD showed that 75% of the total area in 15-30 cm soil layer had BD above >1.6 mg m-3, which indicated the presence of hard pan in subsurface. HC data of subsurface layer also showed that 60% of the area had values<0.5 cm hr-1 which reconfirmed the presence of hard pan. For both surface as well as subsurface soil layers, mostly AWC was >10% which indicated adequate water retention capacity of these soils. However 85% of subsurface had poor soil aeration capacity as indicated NCP range < 10 %. Prediction map of PI for subsurface layer showed that majority of area had PI<0.4 which indicated that expected yield of the crop cannot be more than 70% of the potential yield even under normal or higher levels of fertilizer and water inputs

Malignant meningioma with intra- and extra-cranial extension: A case report

Meningioma is the most common intracranial benign neoplasm. The malignant transformation of this neoplasm is less frequent. Here, we report the case of a 77-year-old male patient who came to our department with a visible mass in the scalp for 1½ years. The mass was gradually increasing in size, soft in nature, not painful, and associated with the left-sided weakness. His multidetector computed tomography showed lesion which is having an intracranial component with the destruction of a vault with extracranial extension. This imaging modality gives a clear-cut picture of the extent of the lesion, nearby structures, and vascularity to give the surgeon proper guidance in two, three, and four dimensions

Cross-Neutralisation of Novel Bombali Virus by Ebola Virus Antibodies and Convalescent Plasma Using an Optimised Pseudotype-Based Neutralisation Assay.

Ebolaviruses continue to pose a significant outbreak threat, and while Ebola virus (EBOV)-specific vaccines and antivirals have been licensed, efforts to develop candidates offering broad species cross-protection are continuing. The use of pseudotyped virus in place of live virus is recognised as an alternative, safer, high-throughput platform to evaluate anti-ebolavirus antibodies towards their development, yet it requires optimisation. Here, we have shown that the target cell line impacts neutralisation assay results and cannot be selected purely based on permissiveness. In expanding the platform to incorporate each of the ebolavirus species envelope glycoprotein, allowing a comprehensive assessment of cross-neutralisation, we found that the recently discovered Bombali virus has a point mutation in the receptor-binding domain which prevents entry into a hamster cell line and, importantly, shows that this virus can be cross-neutralised by EBOV antibodies and convalescent plasma

Weekly paclitaxel, gemcitabine, and external irradiation followed by randomized farnesyl transferase inhibitor R115777 for locally advanced pancreatic cancer.

PURPOSE: The Radiation Therapy Oncology Group (RTOG) multi-institutional Phase II study 98-12, evaluating paclitaxel and concurrent radiation (RT) for locally advanced pancreatic cancer, demonstrated a median survival of 11.3 months and a 1-year survival of 43%. The purpose of the randomized Phase II study by RTOG 0020 was to evaluate the addition of weekly low- dose gemcitabine with concurrent paclitaxel/RT and to evaluate the efficacy and safety of the farnesyl transferase inhibitor R115777 following chemoradiation. PATIENTS AND METHODS: Patients with unresectable, nonmetastatic adenocarcinoma of the pancreas were eligible. Patients in Arm 1 received gemcitabine, 75 mg/m(2)/week, and paclitaxel, 40 mg/m(2)/week, for 6 weeks, with 50.4 Gy radiation (CXRT). Patients in Arm 2 received an identical chemoradiation regimen but then received maintenance R115777, 300 mg twice a day for 21 days every 28 days (CXRT+R115777), until disease progression or unacceptable toxicity. RESULTS: One hundred ninety-five patients were entered into this study, and 184 were analyzable. Grade 4 nonhematologic toxicities occurred in less than 5% of CXRT patients. The most common grade 3/4 toxicity from R115777 was myelosuppression; however, grade 3/4 hepatic, metabolic, musculoskeletal, and neurologic toxicities were also reported. The median survival time was 11.5 months and 8.9 months for the CXRT and CXRT+R115777 arms, respectively. CONCLUSIONS: The CXRT arm achieved a median survival of almost 1-year, supporting chemoradiation as an important therapeutic modality for locally advanced pancreatic cancer. Maintenance R115777 is not effective and is associated with a broad range of toxicities. These findings provide clinical evidence that inhibition of farnesylation affects many metabolic pathways, underscoring the challenge of developing an effective K-ras inhibitor