75 research outputs found

    Are luminescent bacteria suitable for online detection and monitoring of toxic compounds in drinking water and its sources?

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    Biosensors based on luminescent bacteria may be valuable tools to monitor the chemical quality and safety of surface and drinking water. In this review, an overview is presented of the recombinant strains available that harbour the bacterial luciferase genes luxCDABE, and which may be used in an online biosensor for water quality monitoring. Many bacterial strains have been described for the detection of a broad range of toxicity parameters, including DNA damage, protein damage, membrane damage, oxidative stress, organic pollutants, and heavy metals. Most lux strains have sensitivities with detection limits ranging from milligrams per litre to micrograms per litre, usually with higher sensitivities in compound-specific strains. Although the sensitivity of lux strains can be enhanced by various molecular manipulations, most reported detection thresholds are still too high to detect levels of individual contaminants as they occur nowadays in European drinking waters. However, lux strains sensing specific toxic effects have the advantage of being able to respond to mixtures of contaminants inducing the same effect, and thus could be used as a sensor for the sum effect, including the effect of compounds that are as yet not identified by chemical analysis. An evaluation of the suitability of lux strains for monitoring surface and drinking water is therefore provided

    Are bans on political parties bound to turn out badly? A comparative investigation of three 'intolerant' democracies: Turkey, Spain, and Belgium

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    The banning of particular political parties in democratic states is commonly opposed not just on philosophical grounds but also with the practical argument that bans will prove pointless, counterproductive or endanger hard-won achievements. This paper questions that common wisdom — summed up in Hirschman's perversity, futility and jeopardy theses. It conducts a comparative empirical investigation of the consequences of recent bans on 'extremist' parties in three self-styled European democracies — Turkey, Spain and Belgium. It finds that those consequences were not as dire as predicted. This suggests that banning such parties, while by no means always the only or the right thing to do, is not necessarily a mistake, at least on practical rather than normative grounds
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