18,658 research outputs found

    Mass transfer efficiency of a tall and low plate free area liquid pulsed sieve-plate extraction column

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    Acknowledgements The authors would like to acknowledge Chakwal group of industries for funding the project. Ms. Madiha, Ms. Zona, Mr. Sohaib, Mr. Abdullah, Mr. Mudassar, and Mr. Salahuddin also deserve our acknowledgements for their assistance in different ways.Peer reviewedPublisher PD

    Screening-Limited Response of NanoBiosensors

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    Despite tremendous potential of highly sensitive electronic detection of bio-molecules by nanoscale biosensors for genomics and proteomic applications, many aspects of experimentally observed sensor response (S) are unexplained within consistent theoretical frameworks of kinetic response or electrical screening. In this paper, we combine analytic solutions of Poisson-Boltzmann and reaction-diffusion equations to show that the electrical response of nanobiosensor varies logarithmically with the concentration of target molecules, time, the salt concentration, and inversely with the fractal dimension of sensor surface. Our analysis provides a coherent theoretical interpretation of wide variety of puzzling experimental data that have so far defied intuitive explanation.Comment: 7 pages, 2 figure

    Hydrophilic Matrices for Oral Control Drug Delivery

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    Oral controlled drug delivery has gathered tremendous attention over the years due to its many advantages over conventional dosage forms. Polymer-based matrices have become an integral part of the pharmaceutical industry. Hydrophilic matrices are capable of controlling the release of drug over an extended period of time. Hydrophilic polymers, especially the hydrophilic derivatives of cellulose ethers, are frequently used for these applications. Therefore, the objective of this review is to discuss the scientific and physicochemical aspects of these polymeric systems that can affect the drug release from such formulation
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