Sex chromosome positions in human interphase nuclei as studied by in situ hybridization with chromosome specific DNA probes

Two cloned repetitive DNA probes, pXBR and CY1, which bind preferentially to specific regions of the human X and Y chromosome, respectively, were used to study the distribution of the sex chromosomes in human lymphocyte nuclei by in situ hybridization experiments. Our data indicate a large variability of the distances between the sex chromosomes in male and female interphase nuclei. However, the mean distance observed between the X and Y chromosome was significantly smaller than the mean distance observed between the two X-chromosomes. The distribution of distances determined experimentally is compared with three model distributions of distances, and the question of a non-random distribution of sex chromosomes is discussed. Mathematical details of these model distributions are provided in an Appendix to this paper. In the case of a human translocation chromosome (XqterXp22.2::Yq11Y qter) contained in the Chinese hamster x human hybrid cell line 445 x 393, the binding sites of pXBR and CY1 were found close to each other in most interphase nuclei. These data demonstrate the potential use of chromosome-specific repetitive DNA probes to study the problem of interphase chromosome topography

The gall midges (Diptera: Cecidomyiidae) of Mikania glomerata (Asteraceae) in southeastern Brazil

Volume: 103Start Page: 110End Page: 13

A temporal analysis of the relation between organisational commitment and work motivation

Meyer, Becker, and Vandenberghe (2004) recently proposed a model linking work motivation to organisational commitment. Two studies tested these links prospectively with employees from a Canadian telecommunications company and from an Italian autoparts company. Self-determination theory provided the framework to measure work motivation, such that measures of external, introjected and identified regulation, and intrinsic motivation were linked to Allen and Meyer's (1990) and to O'Reilly and Chatman's (1986) tripartite models of organisational commitment. We hypothesised that Time 1 motivation would be related to changes in commitment over time, but that Time 1 commitment would not be related to motivational changes over time. Results supported hypotheses for affective and normative commitment, but not for continuance commitment.</span

Cesium-fountain development at the National Research Council of Canada

NRC publication: Ye

Improved 3-D molasses for tall Cs fountains

NRC publication: Ye

Cold atoms and cesium fountains at NRC

NRC publication: Ye

Hydrogen masers and cesium fountains at NRC

NRC publication: Ye

Narrowband frequency control of an injection-locked diode laser battery

NRC publication: Ye