2,933 research outputs found

    Oxygen Isotopes of Al-Rich Chondrules from Unequilibrated Ordinary Chondrites

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    Al-rich chondrules (ARCs) are a rare constituent of chondrites. They have relatively high bulk Al_2O_3 content (> 10 wt%), which is due to the presence of Al-rich phases, such as plagioclase, spinel, Al-rich glass etc. [1]. ARCs share some chemical and petrologic characteristics with Ca, Al-rich inclusions (CAis), and may represent a genetic link between ferromagnesian chondrules and CAis

    A Universal Point Set for 2-Outerplanar Graphs

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    A point set S⊆R2S \subseteq \mathbb{R}^2 is universal for a class G\cal G if every graph of G{\cal G} has a planar straight-line embedding on SS. It is well-known that the integer grid is a quadratic-size universal point set for planar graphs, while the existence of a sub-quadratic universal point set for them is one of the most fascinating open problems in Graph Drawing. Motivated by the fact that outerplanarity is a key property for the existence of small universal point sets, we study 2-outerplanar graphs and provide for them a universal point set of size O(nlog⁡n)O(n \log n).Comment: 23 pages, 11 figures, conference version at GD 201

    Induction, characterization, and cell transfer of autoimmune tubulointerstitial nephritis

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    Induction, characterization, and cell transfer of autoimmune tubulointerstitial nephritis. Autoimmune tubulointerstitial nephritis (TIN) was induced in Lewis (LEW) rats by immunization with homologous Brown–Norway (BN) rat renal basement membrane (RBM), complete Freund's adjuvant and Bordetella pertussis vaccine. The BN strain has a tubular basement membrane (TBM) antigen (Ag+) detectable by immunofluorescence which is lacking in unmodified LEW rat TBM. Development of TIN in LEW rats correlated with TBM Ag+ immunogens from homologous and heterologous RBM preparations. By day 14 after immunization TIN developed characterized by elevated serum creatinine levels and by tubular destruction with focal, circumscribed lesions containing epithelioid cells, giant cells and mononuclear cell infiltrates. Approximately 60% of the mononuclear cells bore T cell antigens with most cells expressing la markers. Immunofluorescence and elution studies revealed no selective IgG fixation to TBM at day 14 despite high titers of circulating alloantibody reactive with the immunizing TBM. Intravenous transfer of LNC and/or splenic cells (3.5 to 7 × 108) to naive LEW rats resulted in less severe but histologically identical TIN in seven days with T cell subpopulations similar to those seen in the active model. This model strongly suggests an initiating role for cell–mediated immunity in TIN in the rat and may provide a parallel to human TIN
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