Improved pH buffering agent for sodium hypochlorite

Sodium citrate/citric acid was found to be an effective buffer for pH control when used with sodium hypochlorite. The mixture does not corrode aluminum. The buffer appears to form a type of conversion coating that may provide corrosion-resistant properties to aluminum in other applications

Preferences for Prenatal Tests for Cystic Fibrosis: A Discrete Choice Experiment to Compare the Views of Adult Patients, Carriers of Cystic Fibrosis and Health Professionals

As new technologies enable the development of non-invasive prenatal diagnosis (NIPD) for cystic fibrosis (CF), research examining stakeholder views is essential for the preparation of implementation strategies. Here, we compare the views of potential service users with those of health professionals who provide counselling for prenatal tests. A questionnaire incorporating a discrete choice experiment examined preferences for key attributes of NIPD and explored views on NIPD for CF. Adult patients (n = 92) and carriers of CF (n = 50) were recruited from one children’s and one adult NHS specialist CF centre. Health professionals (n = 70) were recruited via an e-mail invitation to relevant professional bodies. The key attribute affecting service user testing preferences was no miscarriage risk, while for health professionals, accuracy and early testing were important. The uptake of NIPD by service users was predicted to be high and includes couples that would currently decline invasive testing. Many service users (47%) and health professionals (55.2%) thought the availability of NIPD for CF would increase the pressure to undergo prenatal testing. Most service users (68.5%) thought NIPD for CF should be offered to all pregnant women, whereas more health professionals (68.2%) thought NIPD should be reserved for known carrier couples. The implications for clinical practice are discussed

Accuracy of information on medication use and adverse drug reactions recorded in pregnancy hand-held records

Background: Pregnancy hand-held records (PHR) are a personally controlled health record utilised in the promotion of continuity of care across pregnancy by providing a single resource for the recording of pregnancy-related health information. Aims: To determine the accuracy of the PHR in relation to information on medications and adverse drug reactions (ADRs) and to examine the frequency and nature of any identified discrepancies. Materials and Methods: A 12-week prospective clinical audit of 300 women admitted to either the antenatal or postnatal ward at a tertiary-level maternity hospital. A detailed medication history was completed for each woman by a pharmacist, with women interviewed about medication use prior to and during their pregnancy as well as any ADRs. The medication history and PHR were compared to identify discrepancies. Results: Medication discrepancies were extremely common, with 254 (84.7%; 95% CI 80.6–88.8%) women having at least one or more medication-related discrepancy involving 686 (55%; 95% CI 52.2–57.8%) prescription and nonprescription medications. Most common reasons for prescription medication discrepancies included the medication details being incomplete (44%), missing (29%) or incorrect (17%). ADRs and allergy discrepancies were also common, identified among 59 (20%; 95% CI 15.5–24.5%) women. Conclusions: The PHR is of low accuracy in relation to the recording of medications and ADRs. This warrants further research to examine the impact of these discrepancies on patient care and outcomes. The identification of strategies for improving the recording of information on medications and ADRs in the PHR is also required.Lauren Nash, Rowena Dixon, Vaughn Eaton, Luke E Grzeskowia

Evolving Issues in Scholarly Communication

As information and communications technologies advance the way that research is conducted and disseminated, how have persistent issues in the process of scholarly communications evolved?https://digitalrepository.unm.edu/hslic-posters-presentations/1065/thumbnail.jp

Fully Dynamic Matching in Bipartite Graphs

Maximum cardinality matching in bipartite graphs is an important and well-studied problem. The fully dynamic version, in which edges are inserted and deleted over time has also been the subject of much attention. Existing algorithms for dynamic matching (in general graphs) seem to fall into two groups: there are fast (mostly randomized) algorithms that do not achieve a better than 2-approximation, and there slow algorithms with \O(\sqrt{m}) update time that achieve a better-than-2 approximation. Thus the obvious question is whether we can design an algorithm -- deterministic or randomized -- that achieves a tradeoff between these two: a $o(\sqrt{m})$ approximation and a better-than-2 approximation simultaneously. We answer this question in the affirmative for bipartite graphs. Our main result is a fully dynamic algorithm that maintains a 3/2 + \eps approximation in worst-case update time O(m^{1/4}\eps^{/2.5}). We also give stronger results for graphs whose arboricity is at most \al, achieving a (1+ \eps) approximation in worst-case time O(\al (\al + \log n)) for constant \eps. When the arboricity is constant, this bound is $O(\log n)$ and when the arboricity is polylogarithmic the update time is also polylogarithmic. The most important technical developement is the use of an intermediate graph we call an edge degree constrained subgraph (EDCS). This graph places constraints on the sum of the degrees of the endpoints of each edge: upper bounds for matched edges and lower bounds for unmatched edges. The main technical content of our paper involves showing both how to maintain an EDCS dynamically and that and EDCS always contains a sufficiently large matching. We also make use of graph orientations to help bound the amount of work done during each update.Comment: Longer version of paper that appears in ICALP 201

Relaxation of strained silicon on Si0.5Ge0.5 virtual substrates

Strain relaxation has been studied in tensile strained silicon layers grown on Si0.5Ge0.5 virtual substrates, for layers many times the critical thickness, using high resolution x-ray diffraction. Layers up to 30 nm thick were found to relax less than 2% by the glide of preexisting 60° dislocations. Relaxation is limited because many of these dislocations dissociate into extended stacking faults that impede the dislocation glide. For thicker layers, nucleated microtwins were observed, which significantly increased relaxation to 14%. All these tensile strained layers are found to be much more stable than layers with comparable compressive strain

Multi-particle Correlations in Quaternionic Quantum Systems

We investigate the outcomes of measurements on correlated, few-body quantum systems described by a quaternionic quantum mechanics that allows for regions of quaternionic curvature. We find that a multi-particle interferometry experiment using a correlated system of four nonrelativistic, spin-half particles has the potential to detect the presence of quaternionic curvature. Two-body systems, however, are shown to give predictions identical to those of standard quantum mechanics when relative angles are used in the construction of the operators corresponding to measurements of particle spin components.Comment: REVTeX 3.0, 16 pages, no figures, UM-P-94/54, RCHEP-94/1

Tasmanian healthcare professionals' & students' capacity for LGBTI + inclusive care: A qualitative inquiry

The health disparities and care needs of lesbian, gay, bisexual, transgender and intersex (LGBTI+) patients are becoming well known. However, healthcare practitioners (HCPs) and medical students across the Global North report limited understanding of this population and express concern about their capacity to meet the needs of LGBTI + patients. To address these gaps in literature and practice, this study draws on qualitative interviews with 12 clinicians and five health professional students exploring their understandings and approaches to LGBTI + inclusive practice in Tasmania, Australia. Through a reflexive thematic analysis, we identified that both practicing clinicians and students did not believe that their training adequately prepared them to treat LGBTI + patients. Other key barriers included reduced awareness of LGBTI + community needs due to the lack of exposure to LGBTI + patients and unfamiliarity with appropriate referral pathways in the regional Tasmanian context. Conversely, factors enabling provision of LGBTI + inclusive care included prior experience working with LGBTI + patients and establishing a network of supportive colleagues and local services. Participants who identified as LGBTI + themselves saw their personal experiences as a strength in supporting LGBTI + patients. While awareness of LGBTI + inclusive health practice is increasing, Tasmanian practitioners report insufficient training and practical difficulties with referral as key challenges

The Standard Model Fermion Spectrum From Complex Projective spaces

It is shown that the quarks and leptons of the standard model, including a right-handed neutrino, can be obtained by gauging the holonomy groups of complex projective spaces of complex dimensions two and three. The spectrum emerges as chiral zero modes of the Dirac operator coupled to gauge fields and the demonstration involves an index theorem analysis on a general complex projective space in the presence of topologically non-trivial SU(n)xU(1) gauge fields. The construction may have applications in type IIA string theory and non-commutative geometry.Comment: 13 pages. Typset using LaTeX and JHEP3 style files. Minor typos correcte

Protecting State Constitutional Rights from Unconstitutional Conditions

The unconstitutional conditions doctrine limits the ability of governments to force individuals to choose between retaining a right and enjoying a government benefit. The doctrine has primarily remained a creature of federal law, with neither courts nor commentators focusing on the potentially important role of state doctrines of unconstitutional conditions. This omission has become especially significant during the COVID-19 pandemic, as actions by state and local governments have presented unconstitutional conditions questions in a range of novel contexts. The overruling of Roe v. Wade and the resulting focus on state constitutional rights to abortion will offer additional new settings for state unconstitutional conditions analysis. As attention turns to distinctive state constitutional rights — in the context of COVID-19 disputes, abortion litigation, and more generally — state courts should develop their own state doctrines of unconstitutional conditions, rather than simply reverting to federal unconstitutional conditions analysis. Three reasons in particular drive this doctrinal claim. First, the unconstitutional conditions doctrine helps to define the scope and weight of a constitutional right. A state court that ignores the unconstitutional conditions doctrine when considering the constitutionality of a state statute or regulation risks undermining the very nature of the right. Second, uncritically adopting federal doctrine ignores the state’s distinctive legal framework, interests, and history, all of which might lead to a deviation from federal law. With respect to the topics on which unconstitutional conditions litigation typically focuses, such as licenses and permits, the federal-state disparities are especially stark. Third, robust legal development in our federal system depends in part upon the interplay of different institutional interpreters. When state courts and federal courts engage in independent interpretative activity, they create the possibility of dialogue and mutual learning. This interpretive interplay enhances federal doctrine, as well as doctrinal development in other states. Given the gaps and inconsistencies in the unconstitutional conditions doctrine, such interjurisdictional enlightenment is especially needed in this area. After explaining why states should develop their own doctrines of unconstitutional conditions, we suggest the relevant considerations that should guide states in formulating their doctrines