Bryophytes of Uganda : 2., new and interesting records

51 hepatics and 46 mosses are reported new to Uganda, including one moss new to Africa, one hepatic and two mosses new to mainland Africa, and 2 hepatics that are otherwise known only from their type collection

Vibrations of the propeller shaft and the rear axle of a passenger car

Digital analysis of the free-free bending vibrations of a propeller shaft and a beam-type rear axle are compared, for different theoretical models, with the results of rig tests. The relative importance of distributed mass, the coupling between the bending and torsional modes and the half shafts of the rear axle are discussed. The relation between the work completed and the programme of work in progress is given briefly at the end of the report

Pip and Pop: When auditory alarms facilitate visual change detection in dynamic settings

Dynamic and complex command and control situations often require the timely recognition of changes in the environment in order to detect potentially malicious actions. Change detection can be challenging within a continually evolving scene, and particularly under multitasking conditions whereby attention is necessarily divided between several subtasks. On-screen tools can assist with detection (e.g., providing a visual record of changes, ensuring that none are overlooked), however, in a high workload environment, this may result in information overload to the detriment of the primary task. One alternative is to exploit the auditory modality as a means to support visual change detection. In the current study, we use a naval air-warfare simulation, and introduce an auditory alarm to coincide with critical visual changes (in aircraft speed/direction) on the radar. We found that participants detected a greater percentage of visual changes and were significantly quicker to detect these changes when they were accompanied by an auditory alarm than when they were not. Furthermore, participants reported that mental demand was lower in the auditory alarm condition, and this was reflected in reduced classification omissions on the primary task. Results are discussed in relation to Wickens’ multiple resource theory of attention and indicate the potential for using the auditory modality to facilitate visual change detection

Inspection of the Lower Half of Wing Lap Joints with EMATs

Detection of fatigue cracks at the fastener holes in the lower portion of the C5A wing lap joint is complicated by lack of a direct line of access, and by the presence of fasteners and sealant material. Furthermore, any successful detection procedure must take into account the wide variation in the geometrical features of the joint. In this work, periodic permanent magnet EMATs (electromagnetic-acoustic transducers) have been employed to excite the n=o horizontally polarized shear mode of the skin at 200 kHz and 250 kHz. These modes are partially transmitted into the overlap region joined by the fastener. Spectral analysis of suitably time gated and apodized portions of the reflected waveform have allowed simulated cracks growing out of fastener holes to be detected, and preliminary sizing algorithms have been developed

Reproducing the general through the local: Lessons from poverty research

Central to research into the conduct of everyday life are issues of generalisation. This chapter focuses on three interrelated forms or manifestations of generalisation, which invoke issues around how macro-level structures and intergroup relations are reproduced through micro-level situations. First, theoretical generalisation constitutes our efforts to enlarge the significance of small-scale exemplars through research by relating local insights to the broader body of academic knowledge. Second, referential generalisation involves relating everyday artefacts produced by our research participants to the broader social context and intergroup relations at play. Third, empathetic generalisation involves promoting witnessing, recognition, and empathy towards people experiencing poverty by people who are not living in poverty. These three forms or elements of generalisation are central to the development of action strategies to address issues of poverty

Radiofrequency thermal ablation of giant placental chorioangioma complicated with fetal hydrops: a case report and successful outcome

ObjectivesChorioangiomas are the most frequently occurring type of benign tumour of the placenta. However, large chorioangiomas greater than 4 cm are rare and can be more frequently associated with serious complications such as: polyhydramnios, hydrops fetalis, fetal anaemia, intrauterine growth restriction, preterm birth, and an increased risk of perinatal mortality. Importantly timely prenatal diagnosis with close surveillance alongside potential intrauterine intervention can prove impactful on pregnancy outcome and fetal survival.Case presentationWe present a case of a 36-year-old female referred to our tertiary fetal medicine unit at 28 weeks’ gestation with a large chorioangioma measuring 9.4×8.8×5.5 cm and ultrasonographic evidence of severe fetal anaemia and fetal hydrops. The patient underwent an intrauterine transfusion and in utero surgical therapy with radiofrequency ablation (RFA). Immediately following the procedure, the fetus sustained a period of bradycardia, followed by asystole. Delivery was expedited via emergency caesarean section. Careful planning and rapid delivery after fetal intervention within the most appropriate surgical setting mitigated risks for the baby and resulted in a positive outcome. The baby was discharged from the neonatal unit on day 84 of life.ConclusionsLarge placental chorioangiomas are a rare occurrence, however, when associated with fetal complications present a high incidence of adverse perinatal outcomes. In utero interventions require careful planning and surgical expertise to ensure improved fetal and neonatal outcomes. To the best of our knowledge this case is the first recorded instance of a successful postnatal outcome following RFA for a large placental chorioangioma, whereby the fetus was complicated by fetal hydrops

Cortical AAV-CNTF gene therapy combined with intraspinal mesenchymal precursor cell transplantation promotes functional and morphological outcomes after spinal cord injury in adult rats

Ciliary neurotrophic factor (CNTF) promotes survival and enhances long-distance regeneration of injured axons in parts of the adult CNS. Here we tested whether CNTF gene therapy targeting corticospinal neurons (CSN) in motor-related regions of the cerebral cortex promotes plasticity and regrowth of axons projecting into the female adult F344 rat spinal cord after moderate thoracic (T10) contusion injury (SCI). Cortical neurons were transduced with a bicistronic adeno-associated viral vector (AAV1) expressing a secretory form of CNTF coupled to mCHERRY (AAV-CNTFmCherry) or with control AAV only (AAV-GFP) two weeks prior to SCI. In some animals, viable or nonviable F344 rat mesenchymal precursor cells (rMPCs) were injected into the lesion site two weeks after SCI to modulate the inhibitory environment. Treatment with AAV-CNTFmCherry, as well as with AAV-CNTFmCherry combined with rMPCs, yielded functional improvements over AAV-GFP alone, as assessed by open-field and Ladderwalk analyses. Cyst size was significantly reduced in the AAV-CNTFmCherry plus viable rMPC treatment group. Cortical injections of biotinylated dextran amine (BDA) revealed more BDA-stained axons rostral and alongside cysts in the AAV-CNTFmCherry versus AAV-GFP groups. After AAV-CNTFmCherry treatments, many sprouting mCherry-immunopositive axons were seen rostral to the SCI, and axons were also occasionally found caudal to the injury site. These data suggest that CNTF has the potential to enhance corticospinal repair by transducing parent CNS populations