2,645 research outputs found

    Model driven testing based on test history

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    We consider software systems consisting of a set of components running as a sequential process. We model such software systems as a special class of transition systems. The difference with existing approaches is that we propose a test procedure based on the structure of the model and the prior test history that can be used for exhaustive testing in an efficient way. On top of that we provide a statistical stopping rule, that is independent of the underlying way of walking through the system, which allows us to stop earlier with a certain statistical reliability.</p

    Ratios of BB and DD Meson Decay Constants in Relativistic Quark Model

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    We calculate the ratios of BB and DD meson decay constants by applying the variational method to the relativistic hamiltonian of the heavy meson. We adopt the Gaussian and hydrogen-type trial wave functions, and use six different potentials of the potential model. We obtain reliable results for the ratios, which are similar for different trial wave functions and different potentials. The obtained ratios show the deviation from the nonrelativistic scaling law, and they are in a pretty good agreement with the results of the Lattice calculations.Comment: 13 pages, 1 Postscript figur

    Impact of Individual Acute Phase Serum Amyloid A Isoforms on HDL Metabolism in Mice

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    The acute phase (AP) reactant serum amyloid A (SAA), an HDL apolipoprotein, exhibits pro-inflammatory activities, but its physiological function(s) are poorly understood. Functional differences between SAA1.1 and SAA2.1, the two major SAA isoforms, are unclear. Mice deficient in either isoform were used to investigate plasma isoform effects on HDL structure, composition, and apolipoprotein catabolism. Lack of either isoform did not affect the size of HDL, normally enlarged in the AP, and did not significantly change HDL composition. Plasma clearance rates of HDL apolipoproteins were determined using native HDL particles. The fractional clearance rates (FCRs) of apoA-I, apoA-II, and SAA were distinct, indicating that HDL is not cleared as intact particles. The FCRs of SAA1.1 and SAA2.1 in AP mice were similar, suggesting that the selective deposition of SAA1.1 in amyloid plaques is not associated with a difference in the rates of plasma clearance of the isoforms. Although the clearance rate of SAA was reduced in the absence of the HDL receptor, scavenger receptor class B type I (SR-BI), it remained significantly faster compared with that of apoA-I and apoA-II, indicating a relatively minor role of SR-BI in SAA’s rapid clearance. These studies enhance our understanding of SAA metabolism and SAA’s effects on AP-HDL composition and catabolism

    Histamine as a marker for hydroxyl radicals

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    During inflammation an influx of neutrophils and release of mediators from mast cells (such as histamine) take place. The stimulated neutrophils can produce reactive oxygen species (ROS). One of these ROS is the highly reactive hydroxyl radical (OH.). It would be interesting to be able to quantify the extent of ROS formation. We investigated if histamine which is present at the inflammation site can serve as an endogenous marker for the formation of OH.. We found that histamine after incubation with OH. gave two distinct products in our HPLC system. One of the products gave the same characteristics as the synthesized 2-imidazolone derivative of histamine. This suggests that this derivative will be formed when histamine is incubated with OH.

    Magnetic Field Dependence of Macroscopic Quantum Tunneling and Coherence of Ferromagnetic Particle

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    We calculate the quantum tunneling rate of a ferromagnetic particle of 100A˚\sim 100 \AA diameter in a magnetic field of arbitrary angle. We consider the magnetocrystalline anisotropy with the biaxial symmetry and that with the tetragonal symmetry. Using the spin-coherent-state path integral, we obtain approximate analytic formulas of the tunneling rates in the small ϵ(=1H/Hc)\epsilon (=1- H/H_c)-limit for the magnetic field normal to the easy axis (θH=π/2\theta_H = \pi/2), for the field opposite to the initial easy axis (θH=π\theta_H = \pi), and for the field at an angle between these two orientations (π/2<<θH<<π\pi/2 << \theta_H << \pi). In addition, we obtain numerically the tunneling rates for the biaxial symmetry in the full range of the angle θH\theta_H of the magnetic field (π/2<θHπ\pi/2 < \theta_H \leq \pi), for the values of \epsilon =0.01 and 0.001.Comment: 25 pages of text (RevTex) and 4 figures (PostScript files), to be published in Phys. Rev.

    Relativistic Generalization of the Gamow Factor for Fermion Pair Production or Annihilation

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    In the production or annihilation of a pair of fermions, the initial-state or final-state interactions often lead to significant effects on the reaction cross sections. For Coulomb-type interactions, the Gamow factor has been traditionally used to take into account these effects. However the Gamow factor needs to be modified when the magnitude of the coupling constant or the relative velocity of two particles increases. We obtain the relativistic generalization of the Gamow factor in terms of the overlap of the Feynman amplitude with the relativistic wave function of two fermions with an attractive Coulomb-type interaction. An explicit form of the corrective factor is presented for the spin-singlet S-wave state. While the corrective factor approaches the Gamow factor in the non-relativistic limit, we found that the Gamow factor significantly over-estimates the effects when the coupling constant or the velocity is large.Comment: 16 pages, 4 figures in LaTe

    Soundness-preserving refinements of service compositions

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    Soundness is one of the well-studied properties of processes; it denotes that a final state can be reached from every state that is reachable from the initial state. Soundness-preserving refinements are important for enabling the compositional design of systems. In this paper we concentrate on refinements of service compositions. We model service compositions using Petri nets, and consider specific pairs of places that belong to different services. Starting from a sound service composition, we show how to check whether such a pair of places can be refined by another sound service composition, so that soundness is preserved through the refinement
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