696 research outputs found

    Silver Coated Bioactive Glass Particles for Wound Healing Applications

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    Hench and colleagues discovered that bone could bond chemically to certain glass compositions in 1969 [1]. This group of glasses is known as bioactive glasses [1]. Some special compositions of bioactive glasses will bond to soft tissues as well as bone [1]. One of the important characteristics of bioactive glasses is their ability to release beneficial ions such as Ca2+, Na+, Zn2+, Sr2+, and PO 43- in the body, which promote self-healing [2]. Bioactive glasses generally contain much less glass former (e.g., SiO2, B2O3 etc.) than conventional glasses [3]. Network modifiers encourage the formation of Non-Bridging Oxygens (NBO) groups. These NBO groups decrease aqueous durability and increase bioactivity [4]. © 2012 IEEE

    Metal concentrations in razor clam Solen dactylus (Von Cosel, 1989) (Bivalvia: Solenidae), sediments and water in Golshahr coast of Bandar Abbas, Persian Gulf

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    In a complementary field study, the concentrations of some metals (Cu, Ag, Pb, Zn, Ni, Co, Mn, Fe, As, Cd, Cr, Mg and Ba) were measured in clam Solen dactylus, sediments and water collected at two stations (Park-e-Qadir, 56° 20/ E, 27° 11/ and Nakhl-e-Nakhoda, 56° 23/ E, 27° 10/ N) of Bandar Abbas coastal waters of the Persian Gulf in November 2008 and February 2009 showing different contamination levels. Although there is little information on metal concentrations in macro-benthic animals in this area, this study, for the first time, reports the accumulation of some metals in S. dactylus in order to introduce this species as a bioindicator for this area. Results indicated that Mg and Fe were the two most abundant metals in clams and sediments. The maximum and minimum metal concentrations in clams belonged to Mg (3850-5040 µgg-1 dry wt) and Ag (0.30-0.40-0.58 µgg-1 dry wt), respectively. There was a significant relationship between the accumulation of metals in clams, sediment and water samples. A significant relationship between clam lengths and concentrations of Cu (positive) and Mg (negative) were observed. Our study also showed that variable metal concentrations were related to different sampling stations, seasons and their interactions as well. Bioaccumulation of metals in clams was significantly different for eight metal elements between start of the gametogenesis and ripeness stages. Our investigation indicated that the clam S. dactylus could be a useful bioindicator for Zinc

    Silver Coated Bioactive Glass Particles for Wound Healing Applications

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    Bioactive glass particles (0.42SiO2-0.15CaO-0.23Na 2O-0.20ZnO) of varying size (\u3c90 \u3eμm and 425-850 μm) were synthesized and coated with silver (Ag) to produce Ag coated particles (PAg). These were compared against the uncoated analogous particles (Pcon.). Surface area analysis determined that Ag coating of the glass particles resulted in increased the surface area from 2.90 to 9.12 m2/g (90 μm) and 1.09-7.71 m2/g (425-850 μm). Scanning electron microscopy determined that the Ag coating remained at the surface and there was little diffusion through the bulk. Antibacterial (Escherichia coli - 13 mm and Staphylococcus epidermidis - 12 mm) and antifungal testing (Candida albicans - 7.7 mm) determined that small Ag-coated glass particles exhibited the largest inhibition zones compared to uncoated particles. pH analysis determined an overall higher pH consider in the smaller particles, where after 24 h the large uncoated and Ag coated particles were 8.27 and 8.74 respectively, while the smaller uncoated and Ag coated particles attained pH values of 9.63 and 9.35 respectively. © Springer Science+Business Media, LLC 2012

    Effects of starvation and re-feeding on some hematological and plasma biochemical parameters of juvenile Persian sturgeon, Acipenser persicus Borodin, 1897

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    The effect of starvation and re-feeding was investigated on growth, hematology and biochemical parameters in juvenile Persian sturgeon (Acipenser persicus). Three hundred and seventy five fish (108±0.63 g) were divided into five feeding groups. The control group (C) was fed to satiation three times a day during the experiment. The four groups were starved for 1 (W1), 2 (W2), 3 (W3), and 4 (W4) weeks respectively, and then fed to satiation during a 4 week re-feeding period. The results indicated that some parameters including final weight, specific growth rate ,body weight increase, plasma enzymes (ALT, Alanine aminotransferase, AST, Aspartat aminotransferase and ALP, Alkaline phosphatise, hematological parameters [Mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration (MCHC), and mean corpuscular hemoglobin (MCH)]were significantly affected by feeding regimes. The plasma cortisol, hematocrit, lymphocytes, neutrophils, eosinophils, and monocytes were not affected by starvation and subsequent re-feeding. These findings showed that short term starvations had no significant negative effects on growth performance, most biochemical and hematological parameters in Persian sturgeon could recover when re-feeding resumed

    Accommodation of transpressional strain in the Arabia-Eurasia collision zone: new constraints from (U-Th)/He thermochronology in the Alborz mountains, north Iran

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    The Alborz range of N Iran provides key information on the spatiotemporal evolution and characteristics of the Arabia-Eurasia continental collision zone. The southwestern Alborz range constitutes a transpressional duplex, which accommodates oblique shortening between Central Iran and the South Caspian Basin. The duplex comprises NW-striking frontal ramps that are kinematically linked to inherited E-W-striking, right-stepping lateral to obliquely oriented ramps. New zircon and apatite (U-Th)/He data provide a high-resolution framework to unravel the evolution of collisional tectonics in this region. Our data record two pulses of fast cooling associated with SW-directed thrusting across the frontal ramps at ~ 18–14 and 9.5-7.5 Ma, resulting in the tectonic repetition of a fossil zircon partial retention zone and a cooling pattern with a half U-shaped geometry. Uniform cooling ages of ~ 7–6 Ma along the southernmost E-W striking oblique ramp and across its associated NW-striking frontal ramps suggests that the ramp was reactivated as a master throughgoing, N-dipping thrust. We interpret this major change in fault kinematics and deformation style to be related to a change in the shortening direction from NE to N/NNE. The reduction in the obliquity of thrusting may indicate the termination of strike-slip faulting (and possibly thrusting) across the Iranian Plateau, which could have been triggered by an increase in elevation. Furthermore, we suggest that ~ 7-6-m.y.-old S-directed thrusting predated inception of the westward motion of the South Caspian Basin
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