Eclipsing high-mass binaries I. Light curves and system parameters for CPD-518946, PISMIS24-1 and HD319702

We present first results of a comprehensive photometric O-star survey performed with a robotic twin refractor at the Universit\"atssternwarte Bochum located near Cerro Armazones in Chile. For three high-mass stars, namely Pismis24-1, CPD-518946 and HD319702, we determined the period through the Lafler-Kinman algorithm and model the light curves within the framework of the Roche geometry. For Pismis24-1, a previously known eclipsing binary, we provide first light curves and determined a photometric period of 2.36 days together with an orbital inclination of 61.8 degrees. The best-fitting model solution to the light curves suggest a detached configuration. With a primary temperature of T1 = 42520K we obtain the temperature of the secondary component as T2 = 41500K. CPD-518946 is another known eclipsing binary for which we present a revised photometric period of 1.96 days with an orbital inclination of 58.4 degrees. The system has likely a semi-detached configuration and a mass ratio q = M1/M2 = 2.8. If we adopt a primary temperature of T1 = 34550K we obtain T2 = 21500K for the secondary component. HD319702 is a newly discovered eclipsing binary member of the young open cluster NGC6334. The system shows well-defined eclipses favouring a detached configuration with a period of 2.0 days and an orbital inclination of 67.5 degrees. Combining our photometric result with the primary spectral type O8 III(f) (T1 = 34000K) we derive a temperature of T2 = 25200K for the secondary component.Comment: 7 pages, 4 figures, accepted for publication in Astronomy and Astrophysic

The broad-line region and dust torus size of the Seyfert 1 galaxy PGC50427

We present the results of a three years monitoring campaigns of the $z = 0.024$ type-1 active galactic nucleus (AGN) PGC50427. Through the use of Photometric Reverberation Mapping with broad and narrow band filters, we determine the size of the broad-line emitting region by measuring the time delay between the variability of the continuum and the H$\alpha$ emission line. The H$\alpha$ emission line responds to blue continuum variations with an average rest frame lag of $19.0 \pm 1.23$ days. Using single epoch spectroscopy we determined a broad-line H$\alpha$ velocity width of 1020 km s$^{-1}$ and in combination with the rest frame lag and adoption a geometric scaling factor $f = 5.5$, we calculate a black hole mass of $M_{BH} \sim 17 \times 10^{6} M_{\odot}$. Using the flux variation gradient method, we separate the host galaxy contribution from that of the AGN to calculate the rest frame 5100\AA~ luminosity at the time of our monitoring campaign. The rest frame lag and the host-subtracted luminosity permit us to derive the position of PGC50427 in the BLR size -- AGN luminosity diagram, which is remarkably close to the theoretically expected relation of $R \propto L^{0.5}$. The simultaneous optical and NIR ($J$ and $K_{s}$) observations allow us to determine the size of the dust torus through the use of dust reverberation mapping method. We find that the hot dust emission ($\sim 1800K$) lags the optical variations with an average rest frame lag of $46.2 \pm 2.60$ days. The dust reverberation radius and the nuclear NIR luminosity permit us to derive the position of PGC50427 on the known $\tau - M{V}$ diagram. The simultaneus observations for the broad-line region and dust thermal emission demonstrate that the innermost dust torus is located outside the BLR in PGC50427, supporting the unified scheme for AGNs. (Abstract shortened, see the manuscript.)Comment: 11 pages, 23 figures, accepted for publication in Astronomy and Astrophysic

The Cyclophilin-Binding Agent Sanglifehrin A Is a Dendritic Cell Chemokine and Migration Inhibitor

Sanglifehrin A (SFA) is a cyclophilin-binding immunosuppressant but the immunobiology of action is poorly understood. We and others have reported that SFA inhibits IL-12 production and antigen uptake in dendritic cells (DC) and exhibits lower activity against lymphocytes. Here we show that SFA suppresses DC chemokine production and migration. Gene expression analysis and subsequent protein level confirmation revealed that SFA suppressed CCL5, CCL17, CCL19, CXCL9 and CXCL10 expression in human monocyte-derived DC (moDC). A systems biology analysis, Onto Express, confirmed that SFA interferes with chemokine-chemokine receptor gene expression with the highest impact. Direct comparison with the related agent cyclosporine A (CsA) and dexamethasone indicated that SFA uniquely suppresses moDC chemokine expression. Competitive experiments with a 100-fold molar excess of CsA and with N-Methyl-Val-4-cyclosporin, representing a nonimmunosuppressive derivative of CsA indicated chemokine suppression through a cyclophilin-A independent pathway. Functional assays confirmed reduced migration of CD4+ Tcells and moDCs to supernatant of SFA-exposed moDCs. Vice versa, SFA-exposed moDC exhibited reduced migration against CCL19. Moreover, SFA suppressed expression of the ectoenzyme CD38 that was reported to regulate DC migration and cytokine production. These results identify SFA as a DC chemokine and migration inhibitor and provide novel insight into the immunobiology of SFA

The progenitor of the FUor-type young eruptive star 2MASS J06593158−0405277

Only a dozen confirmed FU Orionis-type young outbursting stars (FUors) are known today; this explains the interest in the recent FUor eruption of 2MASS J06593158−0405277. Its outburst and expected decline will be subject to numerous studies in the future. Almost equally important for the understanding of the eruption mechanism, however, is the physical characterization of the FUor’s precursor. Here we analyze unpublished archival data and summarize – and partly revise – all relevant photometry from optical to submillimeter wavelengths. Our analysis implies that the FUor is possibly associated with eight T Tauri star candidates and a strong Class 0 source. Adopting a distance of 450 pc for the FUor, we derive a quiescent bolometric luminosity and temperature of Lbol = 4.8 L⊙ and Tbol = 1190 K , typical for young Class II sources. The central star has a temperature of Teff = 4000 K, a mass of 0.75 M⊙, and an age of about 6×105 yr. The SED implies a circumstellar mass of 0.01 – 0.06 M⊙, and the system is surrounded by a faint infrared nebulosity. Our results provide an almost complete picture of a FUor progenitor, supporting the interpretation of future post-outburst studies

Jet Substructure Without Trees

We present an alternative approach to identifying and characterizing jet substructure. An angular correlation function is introduced that can be used to extract angular and mass scales within a jet without reference to a clustering algorithm. This procedure gives rise to a number of useful jet observables. As an application, we construct a top quark tagging algorithm that is competitive with existing methods.Comment: 22 pages, 16 figures, version accepted by JHE

Jet Dipolarity: Top Tagging with Color Flow

A new jet observable, dipolarity, is introduced that can distinguish whether a pair of subjets arises from a color singlet source. This observable is incorporated into the HEPTopTagger and is shown to improve discrimination between top jets and QCD jets for moderate to high pT.Comment: 8 pages, 6 figures (updated to JHEP version