19 research outputs found
FEA BASED ANALYSIS OF SHACKLE FOR OFFSHORE APPLICATION
Nowadays Oil exploration in offshore area is responsible for increasingly greater percentage of production in the world. So mooring Systems play key role. Failure of a single component in a mooring line can produce incalculable damages. Due to environmental loading the mooring changes its position. Each component in the mooring are subjected to angular tensions from top and bottom. It produces strong non linearity in the components. Shackle is the critical part of this mooring system. Analysis of shackle is carried out by consideration of variation in angle from 1Ëš to 5Ëš in Plane and Out of Plane with ANSYS 12. An attempt has been made to analyze the effect of force angle on proof load. As the variation in angle increases from 1Ëš to 5Ëš, proof load decreses. Validation of results are carried out by using horizontal UTM
Ethical leadership of Bank Employee: Does Employee Engage?
The purpose of this qualitative exploratorynbsp casenbsp studynbsp wasnbsp tonbsp identify the real phenomena about employee engagement and ethical leadernbsp strengthennbsp tonbsp providenbsp asnbsp anbsp frameworknbsp fornbsp buildingnbsp potentialnbsp . With the assistance of the Human resourcenbsp Department, this studynbspnbspnbsp identifiednbsp andnbsp conductednbsp tele-conversationnbsp withnbspnbsp 10 executivesnbspnbsp whonbsp hadnbsp atnbsp leastnbsp 5 yearsrsquonbsp experiencenbsp innbsp thenbsp bankingnbsp industry.nbsp Four females and six males were volunteered to participate.nbsp The conversation were recorded, resourcefully transcribed, and reviewed by an external reviewer.nbsp Focusnbsp ofnbsp thenbsp interviewsnbsp wasnbsp drivennbsp bynbsp twonbsp majornbsp researchnbsp questions:nbsp How and why does the ethical leadership important to banking sector? : How and why does the ethical role model important for employee engagement. As a result, ethically accept constitutes leaders and similarities that exist in how these managers from banking sector conceptualize ethical leadership. The information uncover that to most respondents, ethically leaders is vital in light of the individual itself.nbsp Above all else, ethical leader role modelnbsp are consideration to acquirenbsp particular (good) qualities, which are communicated from beginning to end and induced from the leaders #39s own moral basic leadership relationship between employees. While other respondents#39 perspectives on why it is precisely involves being such an #39ethical individual#39 verified various likenesses, open communication and trustworthiness. Policy maker in the banking sectors can include the role model of good practices of leadership that increase level of ethical leadership. The policies also will have an effect on future recruitment, train and retrain which can develop ethical culture and employee engagement due to world globalization and mobility of people. Future study could focus on the other types of leadership and other industries such of self leadership at micro economic level such as the gig economic whereby entrepreneur lead-leadersnbsp themselves with ethical value in small organization that effect the employee engagementnbs
A GCN2-Like Eukaryotic Initiation Factor 2 Kinase Increases the Viability of Extracellular Toxoplasma gondii Parasites â–¿ â€
Toxoplasmosis is a significant opportunistic infection caused by the protozoan parasite Toxoplasma gondii, an obligate intracellular pathogen that relies on host cell nutrients for parasite proliferation. Toxoplasma parasites divide until they rupture the host cell, at which point the extracellular parasites must survive until they find a new host cell. Recent studies have indicated that phosphorylation of Toxoplasma eukaryotic translation initiation factor 2-alpha (TgIF2α) plays a key role in promoting parasite viability during times of extracellular stress. Here we report the cloning and characterization of a TgIF2α kinase designated TgIF2K-D that is related to GCN2, a eukaryotic initiation factor 2α (eIF2α) kinase known to respond to nutrient starvation in other organisms. TgIF2K-D is present in the cytosol of both intra- and extracellular Toxoplasma parasites and facilitates translational control through TgIF2α phosphorylation in extracellular parasites. We generated a TgIF2K-D knockout parasite and demonstrated that loss of this eIF2α kinase leads to a significant fitness defect that stems from an inability of the parasite to adequately adapt to the environment outside host cells. This phenotype is consistent with that reported for our nonphosphorylatable TgIF2α mutant (S71A substitution), establishing that TgIF2K-D is the primary eIF2α kinase responsible for promoting extracellular viability of Toxoplasma. These studies suggest that eIF2α phosphorylation and translational control are an important mechanism by which vulnerable extracellular parasites protect themselves while searching for a new host cell. Additionally, TgIF2α is phosphorylated when intracellular parasites are deprived of nutrients, but this can occur independently of TgIF2K-D, indicating that this activity can be mediated by a different TgIF2K