Integrating Design and Optimization Tools: A Designer Centered Study

Exploring design options for additively manufactured parts generally requires separate, sequentially applied software for design, analysis, and optimization. To evaluate the effect of integrating these capabilities within a single tool we conducted a controlled human subjects study. Three tools with different degrees of integration were created for two test cases of structural trusses, and it was found that increased integration improved quality, speed, and efficiency of the design process. After a quarter of their total time with the problems, 50% of designers with a fully integrated tool had a better design than 75% of other designers ever would. After that point, the top 50% of designers went on to explore a design space unreached with other tools. It appears that integration, and in particular the integration of optimization, leads to better performance by making it possible to explore complex designs and achieve outcomes which would be inaccessible to conventional tools.Lincoln Laborator

Acral myxoinflammatory fibroblastic sarcoma in a renal transplant patient: a case report

Herein, we have reported a case of a 62-year-old patient who presented at 10 months after renal transplantation with a nodular mass on the dorsum of his foot. Local excision was performed and an acral myxoinflammatory fibroblastic sarcoma was diagnosed. This is a rare, low-grade sarcoma with a high rate of local recurrence, sometimes leading to amputation. Metastasis to the lungs and liver has been reported, but is rare. Since our patient received triple immunosuppressive therapy, our major concern was a much more aggressive behavior. However, more than 2 years after excision of the tumor, the patient is still free of disease