8,462 research outputs found
Markov Chain Beam Randomization: a study of the impact of PLANCK beam measurement errors on cosmological parameter estimation
We introduce a new method to propagate uncertainties in the beam shapes used
to measure the cosmic microwave background to cosmological parameters
determined from those measurements. The method, which we call Markov Chain Beam
Randomization, MCBR, randomly samples from a set of templates or functions that
describe the beam uncertainties. The method is much faster than direct
numerical integration over systematic `nuisance' parameters, and is not
restricted to simple, idealized cases as is analytic marginalization. It does
not assume the data are normally distributed, and does not require Gaussian
priors on the specific systematic uncertainties. We show that MCBR properly
accounts for and provides the marginalized errors of the parameters. The method
can be generalized and used to propagate any systematic uncertainties for which
a set of templates is available. We apply the method to the Planck satellite,
and consider future experiments. Beam measurement errors should have a small
effect on cosmological parameters as long as the beam fitting is performed
after removal of 1/f noise.Comment: 17 pages, 23 figures, revised version with improved explanation of
the MCBR and overall wording. Accepted for publication in Astronomy and
Astrophysics (to appear in the Planck pre-launch special issue
Constraining Modified Gravity with Euclid
Future proposed satellite missions as Euclid can offer the opportunity to
test general relativity on cosmic scales through mapping of the galaxy weak
lensing signal. In this paper we forecast the ability of these experiments to
constrain modified gravity scenarios as those predicted by scalar-tensor and
theories. We found that Euclid will improve constraints expected from
the PLANCK satellite on these modified gravity models by two orders of
magnitude. We discuss parameter degeneracies and the possible biases introduced
by modified gravity
Study of the Fusion-Fission Process in the Reaction
Fusion-fission and fully energy-damped binary processes of the
Cl+Mg reaction were investigated using particle-particle
coincidence techniques at a Cl bombarding energy of E
8 MeV/nucleon. Inclusive data were also taken in order to determine the partial
wave distribution of the fusion process. The fragment-fragment correlation data
show that the majority of events arises from a binary-decay process with a
relatively large multiplicity of secondary light-charged particles emitted by
the two primary excited fragments in the exit channel. No evidence is observed
for ternary-breakup processes, as expected from the systematics recently
established for incident energies below 15 MeV/nucleon and for a large number
of reactions. The binary-process results are compared with predictions of
statistical-model calculations. The calculations were performed using the
Extended Hauser-Feshbach method, based on the available phase space at the
scission point of the compound nucleus. This new method uses
temperature-dependent level densities and its predictions are in good agreement
with the presented experimental data, thus consistent with the fusion-fission
origin of the binary fully-damped yields.Comment: 30 pages standard REVTeX file, 10 eps Figures; to be published at the
European Physical Journal A - Hadrons and Nucle
The role of religiousness on substance-use disorder treatment outcomes: a comparison of black and white adolescents
This study compares 41 Black and 124 White adolescents at intake and discharge from a residential treatment program for substance-use disorders. Study data were obtained as part of a larger study (N = 195) that sought to assess the relationship of helping behavior and addiction recovery. This post-hoc analysis aims to identify cultural strengths that may be associated with recovery from substance-use disorders among Black adolescents. Using regression analyses and controlling for the severity of substance use and background variables that distinguish racial groups, religious practices and behaviors at intake were examined. Specifically, Black youth and White youth were compared on treatment outcomes, including alcohol or drug use during treatment, drug craving, 12-Step work, and 12-Step helping. The burden of health and socioeconomic disparities at intake did not disproportionately disfavor Black adolescents. Outcomes related to 12-Step measures were similar between Black and White youth. White adolescents reported higher craving scores at discharge, and Black adolescents were more likely to use drugs during treatment. High levels of religiousness at treatment intake were linked to greater 12-Step work and greater 12-Step helping at discharge. High levels of religiousness at intake were not related to drug use during treatment or to craving scores at discharge. The relationship between intake levels of religiousness and treatment-related outcomes did not differ by race.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437261/Accepted manuscrip
Is the choice of statistical model relevant in the cost estimation of patients with chronic diseases? An empirical approach from the Piedmont Diabetes Registry.
BACKGROUND: Chronic diseases impose large economic burdens. Cost analysis is not straightforward, particularly when the goal is to relate costs to specific patterns of covariates, and to compare costs between diseased and healthy populations. Using different statistical methods this study describes the impact on results and conclusions of analyzing health care costs in a population with diabetes. METHODS: Direct health care costs of people living in Turin were estimated from administrative databases of the Regional Health System. Patients with diabetes were identified through the Piedmont Diabetes Registry. The effect of diabetes on mean annual expenditure was analyzed using the following multivariable models: 1) an ordinary least squares regression (OLS); 2) a lognormal linear regression model; 3) a generalized linear model (GLM) with gamma distribution. Presence of zero cost observation was handled by means of a two part model. RESULTS: The OLS provides the effect of covariates in terms of absolute additive costs due to the presence of diabetes (€ 1,832). Lognormal and GLM provide relative estimates of the effect: the cost for diabetes would be six fold that for non diabetes patients calculated with the lognormal. The same data give a 2.6-fold increase if calculated with the GLM. Different methods provide quite different estimated costs for patients with and without diabetes, and different costs ratios between them, ranging from 3.2 to 5.6. CONCLUSIONS: Costs estimates of a chronic disease vary considerably depending on the statistical method employed; therefore a careful choice of methods to analyze data is required before inferring results
Neuro-hormonal effects of physical activity in the elderly.
Thanks to diagnostic and therapeutic advances, the elderly population is continuously increasing in the western countries. Accordingly, the prevalence of most chronic age-related diseases will increase considerably in the next decades, thus it will be necessary to implement effective preventive measures to face this epidemiological challenge. Among those, physical activity exerts a crucial role, since it has been proven to reduce the risk of cardiovascular diseases, diabetes, obesity, cognitive impairment and cancer. The favorable effects of exercise on cardiovascular homeostasis can be at least in part ascribed to the modulation of the neuro-hormonal systems implicated in cardiovascular pathophysiology. In the elderly, exercise has been shown to affect catecholamine secretion and biosynthesis, to positively modulate the renin-angiotensin-aldosterone system and to reduce the levels of plasma brain natriuretic peptides. Moreover, drugs modulating the neuro-hormonal systems may favorably affect physical capacity in the elderly. Thus, efforts should be made to actually make physical activity become part of the therapeutic tools in the elderly. © 2013 Femminella, de Lucia, Iacotucci, Formisano, Petraglia, Allocca, Ratto, DAmico, Rengo, Pagano, Bonaduce, Rengo and Ferrara
Genetic Characterization of Prairie Grass (\u3cem\u3eBromus Catharticus\u3c/em\u3e Vahl.) Natural Populations
Prairie grass, Bromus catharticus Vahl., is a winter annual or biennial grass, native of South America which is widely distributed in the Pampeana area of Argentina and also cultivated in temperate regions of the world. Morphophysiological traits are currently used to assess the variability from natural populations and cultivars of this species. Molecular markers, which are not influenced by the environment, allow a more accurate assessment of genetic variability. Previous results from our group (Puecher et al., 2001a) showed a narrow genetic basis for the prairie grass cultivars used in Argentina. On the other hand, we also observed that natural populations of this species collected in the typical area where prairie grass is cultivated in Argentina, showed a RAPD variability pattern similar to that previously observed for cultivars (Puecher et al., 2001b). The objective of this work was to establish, using RAPDs, the genetic relationships among prairie grass natural populations including accessions from the margins of the cultivation area of this species in Argentina
- …