Wearable nanosensor-based hardware and software complex for dynamic cardiac monitoring

To date, continuous dynamic monitoring of the cardiovascular system is relevant for improvement of the quality of diagnosis of cardiac diseases. The equipment available for continuous cardiac monitoring operates in the standard frequency range, has a low resolution, and contains filters that limit signals in low and high frequencies. The development of wearable devices and high-resolution methods for dynamic cardiac monitoring to record signals in the range from 0 to 3500 Hz without filtering and averaging is of high priority. In addition, this will allow us to obtain new data on the atria and ventricles of the heart and to detect cardiovascular diseases at an early stage. A wearable hardware and software complex based on nanosensors was developed, and preliminary technical tests of the complex were carried out. An algorithm and a program were developed to detect micropotentials over the entire duration of the ECG signal except for the waves of cardiac pulses and sharp peaks in signal processing. Histograms were built for quantitative evaluation of micropotentials, and the total energy of micropotentials was calculated. Preliminary medical studies were carried out on volunteers

Research into spontaneous activity of myocardial cells under normal and pathological conditions using the hardware and software complex based on nanosensors

Cardiovascular diseases are the leading cause of death in the world. The paper focuses on the capability of a nanosensor-based hardware and software complex (HSC) developed at Tomsk Polytechnic University to measure the activity of myocardial cells from the surface of the human body. A comparative study of nanosensors used in the HSC and conventional AgCl electrodes by FIAB Spa (Florence, Italy) was carried out. It is shown that the value of electromagnetic interference in conventional electrodes is several times higher compared to nanosensors. ECG was recorded using the developed HSC in order to show the possibility to control the activity of myocardial cells

Advanced features of ECG mapping

Cardiovascular diseases are the leading cause of death worldwide. A great number of methods have been developed to monitor the state of the heart, each of which has its own advantages and limitations. One of the most promising method is surface mapping. To improve reliability and informativity of this method, researchers of Medical Engineering Laboratory of TPU developed nanosensors with unique metrological characteristics for non-invasive measurement of ECG signals of microvolt and nanovolt levels. The results of previous studies showed that metrological characteristics of the developed nanosensors significantly exceed those of conventional electrodes. Based on this, nanosensors used for surface ECG mapping will enable qualitative improvement of data obtained and diagnostic capabilities of this method