Alien Registration- Dionne Lausier, Alice R. (Fort Fairfield, Aroostook County)

https://digitalmaine.com/alien_docs/35971/thumbnail.jp

Nonlinear Competition Between Small and Large Hexagonal Patterns

Recent experiments by Kudrolli, Pier and Gollub on surface waves, parametrically excited by two-frequency forcing, show a transition from a small hexagonal standing wave pattern to a triangular ``superlattice'' pattern. We show that generically the hexagons and the superlattice wave patterns bifurcate simultaneously from the flat surface state as the forcing amplitude is increased, and that the experimentally-observed transition can be described by considering a low-dimensional bifurcation problem. A number of predictions come out of this general analysis.Comment: 4 pages, RevTex, revised, to appear in Phys. Rev. Let

Vortex Fluctuations in the Critical Casimir Effect of Superfluid and Superconducting Films

Vortex-loop renormalization techniques are used to calculate the magnitude of the critical Casimir forces in superfluid films. The force is found to become appreciable when size of the thermal vortex loops is comparable to the film thickness, and the results for T < Tc are found to match very well with perturbative renormalization theories that have only been carried out for T > Tc. When applied to a high-Tc superconducting film connected to a bulk sample, the Casimir force causes a voltage difference to appear between the film and bulk, and estimates show that this may be readily measurable.Comment: 4 pages, 5 figures, Revtex 4, typo correctio

Distributed Approximation of Minimum Routing Cost Trees

We study the NP-hard problem of approximating a Minimum Routing Cost Spanning Tree in the message passing model with limited bandwidth (CONGEST model). In this problem one tries to find a spanning tree of a graph $G$ over $n$ nodes that minimizes the sum of distances between all pairs of nodes. In the considered model every node can transmit a different (but short) message to each of its neighbors in each synchronous round. We provide a randomized $(2+\epsilon)$-approximation with runtime $O(D+\frac{\log n}{\epsilon})$ for unweighted graphs. Here, $D$ is the diameter of $G$. This improves over both, the (expected) approximation factor $O(\log n)$ and the runtime $O(D\log^2 n)$ of the best previously known algorithm. Due to stating our results in a very general way, we also derive an (optimal) runtime of $O(D)$ when considering $O(\log n)$-approximations as done by the best previously known algorithm. In addition we derive a deterministic $2$-approximation

Critical Casimir force in 4^4He films: confirmation of finite-size scaling

We present new capacitance measurements of critical Casimir force-induced thinning of $^4$He films near the superfluid/normal transition, focused on the region below $T_{\lambda}$ where the effect is the greatest. $^4$He films of 238, 285, and 340 \AA thickness are adsorbed on N-doped silicon substrates with roughness $\approx 8 {\AA}$. The Casimir force scaling function $\vartheta$, deduced from the thinning of these three films, collapses onto a single universal curve, attaining a minimum $\vartheta = -1.30 \pm 0.03$ at $x=td^{1/\nu}=-9.7\pm 0.8 {\AA}^{1/\nu}$. The collapse confirms the finite-size scaling origin of the dip in the film thickness. Separately, we also confirm the presence down to $2.13 K$ of the Goldstone/surface fluctuation force, which makes the superfluid film $\sim 2 {\AA}$ thinner than the normal film.Comment: 4 pages, 3 figures, submitted to PR

Heterodyne detection of the 752.033-GHz H2O rotational absorption line

A tunable high resolution two stage heterodyne radiometer was developed for the purpose of investigating the intensity and lineshape of the 752.033 GHz rotational transition of water vapor. Single-sideband system noise temperatures of approximately 45,000 K were obtained using a sensitive GaAs Schottky diode as the first stage mixer. First local oscillator power was supplied by a CO2 laser pumped formic acid laser (761.61 GHz), generating an X-band IF signal with theoretical line center at 9.5744 GHz. Second local oscillator power was provided by means of a 3 GHz waveguide cavity filter with only 9 dB insertion loss. In absorption measurements of the H2O taken from a laboratory simulation of a high altitude rocket plume, the center frequency of the 752 GHz line was determined to within 1 MHz of the reported value. A rotational temperature 75 K, a linewidth 5 MHz and a Doppler shift 3 MHz were measured with the line-of-sight intersecting the simulated-plume axis at a distance downstream of 30 nozzle diameters. These absorption data were obtained against continuum background radiation sources at temperatures of 1175 and 300 K

Mixed Methods Evaluation of State Targeted Response to the Opioid Crisis in Ohio

Background: In 2017, the Substance Abuse and Mental Health Services Administration awarded State Targeted Response (STR) grants through the 21st Century Cures Act to help states address the opioid crisis. While there are publications that discuss how each state allocated their STR grant awards, there is a paucity of evaluations illustrating the impact of STR grant activities on clients of opioid use disorder (OUD) treatment, family members of persons living with OUD, community professionals whose work involves addressing OUD, as well as impacts on local communities. This longitudinal qualitative study assessed the impact of STR grant-funded projects on communities in Ohio particularly hard hit by the opioid epidemic. Methods: Data were collected through a mixed research methodology from November 2017 through April 2019. Epidemiologists conducted focus groups and administered surveys in 4 geographically different areas of the state. Study objectives included assessments of community messaging related to opioids, level of perceived stigma for OUD, knowledge of available services and processes for accessing them, and perception of community treatment service needs. Results: A total of 940 respondents participated in 3 cycles (6 months each) of focus groups. Key findings included increased naloxone knowledge and experience, increased proportion of persons living with OUD receiving medication-assisted treatment (MAT), and a 2.5 time increase in the number of reported positive observations of community change. While the level of perceived stigma for OUD remained consistent (moderate) throughout the study, respondents throughout cycles observed an increasing number of community approaches, such as public awareness campaigns and recovery rallies, to impart knowledge, change attitudes, and reduce stigma. Conclusion: Evaluations of STR funded activities and programs could help illustrate the value that additional funding might have over time in reducing stigma related to OUD and increasing knowledge of available treatment services in communities

Na(V)1.5 sodium channel window currents contribute to spontaneous firing in olfactory sensory neurons

Olfactory sensory neurons (OSNs) fire spontaneously as well as in response to odor; both forms of firing are physiologically important. We studied voltage-gated Na+ channels in OSNs to assess their role in spontaneous activity. Whole cell patch-clamp recordings from OSNs demonstrated both tetrodotoxin-sensitive and tetrodotoxin-resistant components of Na+ current. RT-PCR showed mRNAs for five of the nine different Na+ channel α-subunits in olfactory tissue; only one was tetrodotoxin resistant, the so-called cardiac subtype NaV1.5. Immunohistochemical analysis indicated that NaV1.5 is present in the apical knob of OSN dendrites but not in the axon. The NaV1.5 channels in OSNs exhibited two important features: 1) a half-inactivation potential near −100 mV, well below the resting potential, and 2) a window current centered near the resting potential. The negative half-inactivation potential renders most NaV1.5 channels in OSNs inactivated at the resting potential, while the window current indicates that the minor fraction of noninactivated NaV1.5 channels have a small probability of opening spontaneously at the resting potential. When the tetrodotoxin-sensitive Na+ channels were blocked by nanomolar tetrodotoxin at the resting potential, spontaneous firing was suppressed as expected. Furthermore, selectively blocking NaV1.5 channels with Zn2+ in the absence of tetrodotoxin also suppressed spontaneous firing, indicating that NaV1.5 channels are required for spontaneous activity despite resting inactivation. We propose that window currents produced by noninactivated NaV1.5 channels are one source of the generator potentials that trigger spontaneous firing, while the upstroke and propagation of action potentials in OSNs are borne by the tetrodotoxin-sensitive Na+ channel subtypes.This work was aided by support from Boston University, the Rocky Mountain Taste and Smell Center Core for Cellular Visualization and Analysis [National Institute on Deafness and Other Communication Disorders (NIDCD) P30 DC-04657; D. Restrepo, principal investigator], and NIDCD Grants DC-04863 to V. Dionne and DC-006070 to D. Restrepo and T. E. Finger. (Boston University; P30 DC-04657 - Rocky Mountain Taste and Smell Center Core for Cellular Visualization and Analysis [National Institute on Deafness and Other Communication Disorders (NIDCD)]; DC-04863 - Rocky Mountain Taste and Smell Center Core for Cellular Visualization and Analysis [National Institute on Deafness and Other Communication Disorders (NIDCD)]; DC-006070 - Rocky Mountain Taste and Smell Center Core for Cellular Visualization and Analysis [National Institute on Deafness and Other Communication Disorders (NIDCD)])https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122723/Accepted manuscrip