Precise time and time interval users, requirements and specifications

The functional areas of application of Precise Time and Time Interval (PTTI) were considered and expanded. A comprehensive overview of the PTTI requirements and applications would provide an opportunity for individuals working in a specific functional area. Mutual problems, requirements, applications or successes shared by those in other functional areas were studied. Based upon the results of a two year study a compendium of PTTI requirements, applications and the means of meeting the requirements among Department of Defense components, other government agencies and major commercial users was compiled and is presented. It was found that the planning process for PTTI support for new acquisitions or new programs was less than a well defined, coordinated process. The processes are described in general terms and a generic model for requirements determination and subsequent coordination which may enhance the planning process and introduce cost benefits to the program is also presented

Department of Defense Precise Time and Time Interval program improvement plan

The United States Naval Observatory is responsible for ensuring uniformity in precise time and time interval operations including measurements, the establishment of overall DOD requirements for time and time interval, and the accomplishment of objectives requiring precise time and time interval with minimum cost. An overview of the objectives, the approach to the problem, the schedule, and a status report, including significant findings relative to organizational relationships, current directives, principal PTTI users, and future requirements as currently identified by the users are presented

STRUCTURE AND TRANSPORT IN TRIALKYLTRIAZOLIUM IONIC LIQUIDS: A COMBINED PFG-NMR DIFFUSION AND CONDUCTIVITY STUDY

Ionic liquids (ILs), the class of salts with melting points below 100 °C, are promising alternatives to molecular solvents. Their great chemical tuneability opens the possibility of tailoring ILs for specific tasks; however, data from systematic structure-property studies of ILs, as well as a more complete understanding of the liquid structure and interionic interactions within ILs, are required for the rational design of ILs. In this thesis, a systematic study of the effect of alkyl chain length and alkyl chain branching on the transport properties and carbon dioxide solubility in trialkyltriazolium ionic liquids is described. The viscosities, diffusion coefficients, and conductivities of 15 1,2,4-trialkyl-1,2,3-triazolium bis(trifluoromethylsulfonyl)imide ILs are reported, and are found to be greatly reduced in ILs that incorporate multiple branched alkyl groups on the cation. The interrelationships among the transport properties are analyzed by comparing the deviations of the transport properties of each IL from Walden’s Rule, the Stokes-Einstein equation, and the Nernst-Einstein equation. Preliminary evidence is given for a connection between the formation of polar and non-polar nanodomains within ILs, and the Nernst-Einstein deviation ratio. Henry’s Law constants for the solubility of carbon dioxide in the ILs are reported and found to be most strongly correlated to the molar volume of the IL; evidence supporting a relationship between the Nernst-Einstein deviation ratio and carbon dioxide solubility for a given IL is not found

Dehydrator exhaust recirculation for energy savings

The Oklahoma Cooperative Extension Service periodically issues revisions to its publications. The most current edition is made available. For access to an earlier edition, if available for this title, please contact the Oklahoma State University Library Archives by email at [email protected] or by phone at 405-744-6311

Dehydrator exhaust recirculation for energy savings

The Oklahoma Cooperative Extension Service periodically issues revisions to its publications. The most current edition is made available. For access to an earlier edition, if available for this title, please contact the Oklahoma State University Library Archives by email at [email protected] or by phone at 405-744-6311

Dehydrator optimization: Reduction of energy use and carbon emissions

The Oklahoma Cooperative Extension Service periodically issues revisions to its publications. The most current edition is made available. For access to an earlier edition, if available for this title, please contact the Oklahoma State University Library Archives by email at [email protected] or by phone at 405-744-6311

Knowledge-based variable selection for learning rules from proteomic data

<p>Abstract</p> <p>Background</p> <p>The incorporation of biological knowledge can enhance the analysis of biomedical data. We present a novel method that uses a proteomic knowledge base to enhance the performance of a rule-learning algorithm in identifying putative biomarkers of disease from high-dimensional proteomic mass spectral data. In particular, we use the Empirical Proteomics Ontology Knowledge Base (EPO-KB) that contains previously identified and validated proteomic biomarkers to select <it>m/z</it>s in a proteomic dataset prior to analysis to increase performance.</p> <p>Results</p> <p>We show that using EPO-KB as a pre-processing method, specifically selecting all biomarkers found only in the biofluid of the proteomic dataset, reduces the dimensionality by 95% and provides a statistically significantly greater increase in performance over no variable selection and random variable selection.</p> <p>Conclusion</p> <p>Knowledge-based variable selection even with a sparsely-populated resource such as the EPO-KB increases overall performance of rule-learning for disease classification from high-dimensional proteomic mass spectra.</p

NA

http://www.archive.org/details/infraredemissivi00hougU.S. Navy (U.S.N.) author.U.S. Marine Corps (U.S.M.C.) author

Carbonic Anhydrase I Is Recognized by an SOD1 Antibody upon Biotinylation of Human Spinal Cord Extracts

We recently reported the presence of a novel 32 kDa protein immunoreactive to a copper, zinc superoxide dismutase (SOD1) antibody within the spinal cord of patients with amyotrophic lateral sclerosis (ALS). This unique protein species was generated by biotinylation of spinal cord tissue extracts to detect conformational changes of SOD1 specific to ALS patients. To further characterize this protein, we enriched the protein by column chromatography and determined its protein identity by mass spectrometry. The protein that gave rise to the 32 kDa species upon biotinylation was identified as carbonic anhydrase I (CA I). Biotinylation of CA I from ALS spinal cord resulted in the generation of a novel epitope recognized by the SOD1 antibody. This epitope could also be generated by biotinylation of extracts from cultured cells expressing human CA I. Peptide competition assays identified the amino acid sequence in carbonic anhydrase I responsible for binding the SOD1 antibody. We conclude that chemical modifications used to identify pathogenic protein conformations can lead to the identification of unanticipated proteins that may participate in disease pathogenesis