13 research outputs found
Probing Structural Features of Alzheimer’s Amyloid-β Pores in Bilayers Using Site-Specific Amino Acid Substitutions
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Amyloid-β-Induced Ion Flux in Artificial Lipid Bilayers and Neuronal Cells: Resolving a Controversy
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Synthesis, DFT and POM analyses of cytotoxicity activity of alpha-camidophosphonates derivatives: Identification of potential antiviral O,O-pharmacophore site
No full textIn the present study, we investigated the cytotoxic activity of three compounds prepared starting from amino acids. These derivatives were evaluated for their in vitro antitumor activity against human cell lines (PRI, K562 and JURKAT). Their cytotoxicity was also evaluated at different concentrations on several cell lines. On the other hand, DFT calculation has been used to analyze the electronic and geometric characteristics. The HOMO, LUMO and gap energies were also deduced for the stable structure for each compound. These results will be correlated with the experimental values. The bioinformatic POM (Petra/Osiris/Molinspiration) analyses of the relative cytotoxicity of these derivatives are reported in comparison to Chlorambucil. (C) 2019 Published by Elsevier B.V
Urinary tract infection during pregnancy: current concepts on a common multifaceted problem
No full textOutcome of subsequent IVF cycles after antibiotic therapy following previously failed IVF cycles. Study II
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Vitamin D and its relation with ionic calcium, parathyroid hormone, maternal and neonatal characteristics in pregnancy after roux-en-Y gastric bypass
No full textThe children of dialysis: live-born babies from on-dialysis mothers in Italy--an epidemiological perspective comparing dialysis, kidney transplantation and the overall population
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