7 research outputs found

    A novel phantom design for brachytherapy quality Assurance

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    Background: One major challenge in brachytherapy is to verify the accuracy of dose distributions calculated by the treatment planning system. In this project, a new phantom design has been introduced for quality assurance of dose distributions in gynocological (GYN) brachytherapy implants using EBT GafChromic film. Materials and Methods: This phantom has been designed and fabricated from 90 slabs of 18�16�0.2 cm3 Perspex to accommodate a tandem and ovoids assembly, which is normally used for GYN brachytherapy treatment. In addition, this phantom design is allowing the use EBT GafChromic films for dosimetric verification of GYN implants with Cs-137 Selectron LDR system. With this assembly, GafChromic films were exposed using a plan designed to deliver 2.5 Gy dose to point "A" in Manchester system for tandem and ovoids configurations and to deliver 1.5 Gy of dose to 0.5 cm distance from the lateral surface of ovoids for using ovoid-pair. The measured dose distributions with GafChromic films were compared with the TPS isodose lines both numerically and spatially. For a quantitative analysis of the results, the measured doses values at several points of interest were evaluated with the treatment planning data and values obtained following the TG-43 dose calculation formalism. Results: The results of these investigations have indicated that the new phantom design enables us to measure differences of greater than ±6 for LDR brachytherapy GYN treatments. Conclusion: The new phantom design could be utilized for the QA procedure of the brachytherapy remote after loading systems to confirm the accuracy of dose distribution in GYN implants

    Dose distribution verification for GYN brachytherapy using EBT Gafchromic film and TG-43 calculation

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    Aim Verification of dose distributions for gynecological (GYN) brachytherapy implants using EBT Gafchromic film. Background One major challenge in brachytherapy is to verify the accuracy of dose distributions calculated by a treatment planning system. Materials and methods A new phantom was designed and fabricated using 90 slabs of 18 cm � 16 cm � 0.2 cm Perspex to accommodate a tandem and Ovoid assembly, which is normally used for GYN brachytherapy treatment. This phantom design allows the use of EBT Gafchromic films for dosimetric verification of GYN implants with a cobalt-60 HDR system or a LDR Cs-137 system. Gafchromic films were exposed using a plan that was designed to deliver 1.5 Gy of dose to 0.5 cm distance from the lateral surface of ovoids from a pair of ovoid assembly that was used for treatment vaginal cuff. For a quantitative analysis of the results for both LDR and HDR systems, the measured dose values at several points of interests were compared with the calculated data from a commercially available treatment planning system. This planning system was utilizing the TG-43 formalism and parameters for calculation of dose distributions around a brachytherapy implant. Results The results of these investigations indicated that the differences between the calculated and measured data at different points were ranging from 2.4 to 3.8 for the LDR Cs-137 and HDR Co-60 systems, respectively. Conclusion The EBT Gafchromic films combined with the newly designed phantom could be utilized for verification of the dose distributions around different GYN implants treated with either LDR or HDR brachytherapy procedures. © 2016 Greater Poland Cancer Centr

    The epidemiology of hepatitis C virus in Iran: Systematic review and meta-analyses

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